Results 191 to 200 of about 49,331 (295)
Acetyl-coenzyme A carboxylase – an attractive enzyme for biotechnology [PDF]
Jan Podkowiński, Aleksander Tworak
openalex
Acetyl-coenzyme A formation in the tissues of the developing lamb [PDF]
R V Brierley +2 more
openalex +1 more source
Esophageal squamous cell carcinoma urgently requires new therapeutic strategies. Adenosine diphosphate‐ribosylation factor‐like protein 5B (ARL5B) is identified as a novel oncogene that remodels fatty acid metabolism through the ras homologous‐associated coiled‐coil containing protein kinase 1 (ROCK1)–sterol regulatory element‐binding protein 1 (SREBP1)
Xinyue Ma +12 more
wiley +1 more source
This study unveils a novel GAA (GCN5‐ADA2‐ACL) complex that forms nuclear condensates to boost local acetyl‐CoA, facilitating histone acetylation and gene transcription in rice meristems. The research underscores the role of ADA2's disordered region in complex condensation and ACL's role in acetyl‐CoA production.
Yaping Yue +11 more
wiley +1 more source
Farnesoid X Receptor Agonism, Acetyl-Coenzyme A Carboxylase Inhibition, and Back Translation of Clinically Observed Endpoints of De Novo Lipogenesis in a Murine NASH Model. [PDF]
Gapp B +15 more
europepmc +1 more source
Metabolism‐Regulating Nanomedicines for Cancer Therapy
This review highlights metabolism‐regulating nanomedicines designed to target glycolytic, lipid, amino acid, and nucleotide pathways in tumors. By incorporating metabolism‐regulating agents into versatile nanocarriers such as liposomes, micelles, dendrimers, and engineered bacteria, these platforms achieve targeted delivery, controlled release ...
Xiao Wu, Shiyi Geng, Jian Yang
wiley +1 more source
Leucine Signals to mTORC1 via Its Metabolite Acetyl-Coenzyme A. [PDF]
Son SM +6 more
europepmc +1 more source
Biological Conversion of Formate to Organic Compounds: Toward a Sustainable Formate Bioeconomy
Formate bioconversion plays a crucial role in achieving renewable resource utilization and sustainable development. To tap its full potential, it is important to identify the most appropriate microbial hosts for incorporating formate into building blocks, design the most promising metabolic pathways for transmitting formate into central carbon ...
Jinyi Qian +3 more
wiley +1 more source
Regulatory mechanism of O‐linked N‐acetylglucosamine protein modification on autophagy in cancer
O‐GlcNAcylation serves as a nutrient and stress sensor that dynamically regulates autophagy at multiple stages in cancer cells. It fine‐tunes autophagy initiation, maturation and fusion by modifying key proteins such as ULK1, ATG4B and SNAP‐29. Context‐dependent O‐GlcNAcylation promotes tumour adaptation and therapy resistance via autophagy remodelling.
Yizhan Li +5 more
wiley +1 more source
Structure/function studies of rat acetyl-coenzyme A carboxylase
Robert A. Winz
openalex +1 more source

