Results 111 to 120 of about 199,012 (297)
THE EFFECT OF PANTOTHENIC ACID DEFICIENCY ON ACETYLATION IN RATS
Thomas R. Riggs, D.M. Hegsted
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A K, Balls, F L, Aldrich
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This study reveals that Arabidopsis telomere repeat binding proteins (TRBs) form two closely related complexes. These complexes mediate H3K4me3 demethylation and transcriptional repression through a positive feedback loop and cooperate with PEAT and PRC2 complexes to regulate multiple histone modifications and gene expression across the genome ...
Qi Wang +7 more
wiley +1 more source
THE RACEMIZATION OF AMINO ACIDS ON ACETYLATION WITH KETENE
Richard W. Jackson, William M. Cahill
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HIFU‐Driven Targeted Pyroptosis Therapy in Basal‐Like Breast Cancer
This study presents a HIFU‐driven pyroptosis strategy for BLBC treatment. Combining HIFU with platelet‐membrane hybridized liposomes encapsulating mitoxantrone enhances tumor targeting and efficacy. The synergistic treatment modulates key epigenetic regulators and activates the pyroptotic pathway through ROS generation and inflammasome signaling ...
Xiaomin Su +13 more
wiley +1 more source
FRIEDEL AND CRAFTS ACETYLATION OF METHYL ,β-RESORCYLATE AND FRIES :MIGRATION OF METHYL 2-HYDROXY-4- ACETOXVBENZOATE IN PRESENCE OF BORON TRIFLUORIDE [PDF]
P. L. TRIVEDI
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STK25 Loss Augments Anti‐PD‐1 Therapy Efficacy by Regulating PD‐L1 Stability in Colorectal Cancer
This study demonstrates that STK25 depletion facilitates CRC immune escape through the inhibition of PD‐L1 Ser283 phosphorylation‐mediated ubiquitination, and promotes tumor growth. Furthermore, these findings identify STK25 as a potential therapeutic target to trigger antitumor immunity and promote immunotherapy efficacy. Abstract Tumor immune evasion
Xiaowen Qiao +20 more
wiley +1 more source
Glioblastoma (GBM) is the most aggressive primary brain tumor, with glioma stem cells (GSCs) driving treatment resistance. This study reveals that lactate promotes histone lactylation (H3K18la) at the VRK1 promoter, regulating GSC stemness and proliferation via the H3K18la/VRK1/YBX1/SOX2 pathway. The VRK1‐targeted nanoliposome A/TMZ‐siVRK1 demonstrates
Jinna Li +4 more
wiley +1 more source
BIOLOGICAL ACETYLATION OF NATURAL AMINO ACIDS
Konrad Bloch, Ernest Borek
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Native thioredoxin‐1 (TRX) stimulates proliferation and rescues stem cells and cancer cells from multiple stressors by suppressing p53 and inhibiting ferroptosis via GPX4/SLC7A11 upregulation mediated by enhanced KLF4 expression and p53 promoter binding.
Jian Wu +18 more
wiley +1 more source

