Results 121 to 130 of about 9,200 (244)

Effect of l-carnitine on the kinetics of carnitine, acylcarnitines and butyrobetaine in long-term haemodialysis [PDF]

open access: yes, 2017
Background. The current study was performed to investigate the kinetics of carnitine, individual acylcarnitines and butyrobetaine in patients on haemodialysis. Methods. Eight stable long-term haemodialysis patients were studied under basal conditions (no
Dickenmann, Michael   +4 more
core  

N-acetyl-cysteine, a drug that enhances the endogenous activation of group-II metabotropic glutamate receptors, inhibits nociceptive transmission in humans. [PDF]

open access: yes, 2015
Emerging research seeking novel analgesic drugs focuses on agents targeting group-II metabotropic glutamate receptors (mGlu2 and mGlu3 receptors). N-Acetylcysteine (NAC) enhances the endogenous activation of mGlu2/3 receptors by activating the glial ...
BATTAGLIA, Giuseppe   +8 more
core   +1 more source

Transcriptomic and metabolomic analyses reveal the spatial role of carnitine metabolism in the progression of hepatitis B virus cirrhosis to hepatocellular carcinoma

open access: yesFrontiers in Microbiology
IntroductionLiver cirrhosis (LC) and hepatocellular carcinoma (HCC) resulting from chronic hepatitis B virus (HBV) infection are major health concerns.
Pengxiang Gao   +4 more
doaj   +1 more source

Genes involved in carnitine synthesis and carnitine uptake are up-regulated in the liver of sows during lactation [PDF]

open access: yes, 2013
BACKGROUND:Convincing evidence exist that carnitine synthesis and uptake of carnitine into cells is regulated by peroxisome proliferator-activated receptor alpha (PPARA), a transcription factor which is physiologically activated during fasting or energy ...
Becker, Sabrina   +7 more
core   +2 more sources

Proton NMR-Based Metabolite Analyses of Archived Serial Paired Serum and Urine Samples from Myeloma Patients at Different Stages of Disease Activity Identifies Acetylcarnitine as a Novel Marker of Active Disease

open access: yesPLoS ONE, 2013
Background Biomarker identification is becoming increasingly important for the development of personalized or stratified therapies. Metabolomics yields biomarkers indicative of phenotype that can be used to characterize transitions between health and ...
A. Lodi   +7 more
semanticscholar   +1 more source

Metabonomics and Intensive Care [PDF]

open access: yes, 2016
This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency medicine 2016. Other selected articles can be found online at http://www.biomedcentral.com/collections/annualupdate2016.
A Gupta   +43 more
core   +3 more sources

Associations between fatty acid oxidation, hepatic mitochondrial function, and plasma acylcarnitine levels in mice

open access: yesNutrition & Metabolism, 2018
Background The 4-thia fatty acid tetradecylthiopropionic acid (TTP) is known to inhibit mitochondrial β-oxidation, and can be used as chemically induced hepatic steatosis-model in rodents, while 3-thia fatty acid tetradecylthioacetic acid (TTA ...
Bodil Bjørndal   +5 more
doaj   +1 more source

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