Results 1 to 10 of about 137,412 (311)

LC-HRMS Profiling and Antidiabetic, Anticholinergic, and Antioxidant Activities of Aerial Parts of Kınkor (Ferulago stellata)

Molecules, 2021
Kınkor (Ferulago stellata) is Turkish medicinal plant species and used in folk medicine against some diseases. As far as we know, the data are not available on the biological activities and chemical composition of this medicinal plant. In this study, the
Hatice Kızıltaş, Zeynebe Bingol, Ahmet Ceyhan Gören, Leyla Polat Kose, Lokman Durmaz, Fevzi Topal, Saleh H. Alwasel, İlhami Gulcin   +7 more
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CSF Cholinergic Index, a New Biomeasure of Treatment Effect in Patients With Alzheimer’s Disease

Frontiers in Molecular Neuroscience, 2019
Alzheimer’s disease (AD) is a progressive disease with early degeneration of the central cholinergic neurons. Currently, three of four AD drugs act by inhibiting the acetylcholine (ACh) degrading enzyme, acetylcholinesterase (AChE).
Azadeh Karami, Maria Eriksdotter, Maria Eriksdotter, Ahmadul Kadir, Ahmadul Kadir, Ove Almkvist, Agneta Nordberg, Agneta Nordberg, Taher Darreh-Shori   +8 more
doaj   +1 more source

Anticholinesterase Activities of Different Solvent Extracts of Brewer’s Spent Grain

Foods, 2021
Cholinesterases, involved in acetylcholine catabolism in the central and peripheral nervous system, have been strongly linked with neurodegenerative diseases. Current therapeutic approaches using synthetic drugs present several side effects. Hence, there
Rares I. Birsan, Peter Wilde, Keith W. Waldron, Dilip K. Rai   +3 more
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A Comprehensive Review of Cholinesterase Modeling and Simulation

Biomolecules, 2021
The present article reviews published efforts to study acetylcholinesterase and butyrylcholinesterase structure and function using computer-based modeling and simulation techniques.
Danna De Boer, Nguyet Nguyen, Jia Mao, Jessica Moore, Eric J. Sorin   +4 more
doaj   +1 more source

Stability of acetylcholinesterase (AChE) activity in blood: the effect of the preservative agent

Archives of Forensic Medicine and Criminology
Fluoride anions are believed to inhibit acetylcholinesterase activity, thus there is a possibility that the activity may be affected by blood sampling into vials containing sodium fluoride as an ...
Kaja Tusiewicz, Paweł Szpot, Olga Wachełko, Marcin Zawadzki   +3 more
doaj   +1 more source

The relationship between deltamethrin-induced behavioral changes and acetylcholinesterase activity in zebrafish embryos or larvae based on transcriptome

Frontiers in Veterinary Science
BackgroundDeltamethrin (DM) is a broad-spectrum insecticide that is widely used to control agricultural pests. Recently, DM has posed a potential threat to the health of infants and young children, and this is because of the environmental and food ...
Chunyu Liu, Yantong Guo, Xue Zhang, Hongsong Chen, Maomao Han, Han Wang, Jieyao Niu, Jinfei He, Jingfeng Yang, Wu Dong, Jiangdong Xue   +10 more
doaj   +1 more source

Acute toxicity of a deltamethrin based pesticide (DBP) to the Neotropical electric fish Microsternarchus cf. bilineatus (Gymnotiformes) [PDF]

Acta Amazonica
Deltamethrin is a pyrethroid insecticide widely used in pest control in Brazilian agriculture. The intensive and disordered use of this pesticide in the Amazon region can drive it into aquatic ecosystems in several ways, but mainly by runoff and leaching.
Valesca de Souza CHAVES, Jaydione Luiz MARCON, Wallice Paxiúba DUNCAN, José Antônio ALVES-GOMES   +3 more
doaj   +2 more sources

Indene-Derived Hydrazides Targeting Acetylcholinesterase Enzyme in Alzheimer’s: Design, Synthesis, and Biological Evaluation

Pharmaceutics, 2022
As acetylcholinesterase (AChE) plays a crucial role in advancing Alzheimer’s disease (AD), its inhibition is a promising approach for treating AD.
Shraddha Manish Gupta, Ashok Behera, Neetesh K. Jain, Devendra Kumar, Avanish Tripathi, Shailesh Mani Tripathi, Somdutt Mujwar, Jeevan Patra, Arvind Negi   +8 more
doaj   +1 more source

Impact of Insecticides at Sublethal Concentrations on the Enzyme Activities in Adult Musca domestica L.

Toxics, 2023
Nowadays, the use of pesticides is, as before, the most common way to control arthropod plant pests and the ectoparasites of animals. The sublethal effects of pesticides on insects can appear at different levels, from genetics to populations, and the ...
Anna Kinareikina, Elena Silivanova
doaj   +1 more source

Chemical composition, antibiofilm, cytotoxic, and anti-acetylcholinesterase activities of Myrtus communis L. leaves essential oil [PDF]

, 2022
Lucia Caputo, Francesca Capozzolo, Giuseppe Amato, Vincenzo De Feo, Florinda Fratianni, Giovanni Vivenzio, Filomena Nazzaro   +6 more
openalex   +1 more source