Results 111 to 120 of about 176,114 (393)

A Complete Survey of Glycoalkaloids Using LC-FTICR-MS and IRMPD in a Commercial Variety and a Local Landrace of Eggplant (Solanum melongena L.) and their Anticholinesterase and Antioxidant Activities

Toxins, 2019
Eggplant contains glycoalkaloids (GAs), a class of nitrogen-containing secondary metabolites of great structural variety that may have both adverse and beneficial biological effects.
Filomena Lelario, Susanna De Maria, Anna Rita Rivelli, Daniela Russo, Luigi Milella, Sabino Aurelio Bufo, Laura Scrano   +6 more
doaj   +1 more source

Review: Dystroglycan in the Nervous System [PDF]

, 2007
Dystroglycan is part of a large complex of proteins, the dystrophin-glycoprotein complex, which has been implicated in the pathogenesis of muscular dystrophies for a long time.
Matthias Samwald
core   +2 more sources

The Phenolic Content and Bioactivity Assessment of Rubus sanctus Schreber Species with Potential for Food and Ethnopharmacological Uses

Chemistry &Biodiversity, EarlyView.
ABSTRACT In this study, the phytochemical content and various biological activities of Rubus sanctus Schreber species, widely distributed in Turkiye and used in folk medicine, were determined. The ethanol extracts of the root and aerial parts of the species were prepared and their bioactive phytochemical composition was identified by liquid ...
Ismail Yener
wiley   +1 more source

Uso de plaguicidas inhibidores de acetilcolinesterasa en once entidades territoriales de salud en Colombia, 2002-2005

Biomédica: revista del Instituto Nacional de Salud, 2010
Introducción. Por ser los plaguicidas anticolinesterásicos una causa importante de intoxicación y de muerte por intoxicación en los países en vía de desarrollo, el Instituto Nacional de Salud implementó el Programa de Vigilancia Epidemiológica de ...
Omayda Cárdenas, Elizabeth Silva, Jaime Eduardo Ortiz   +2 more
doaj   +1 more source

SchussenAktivplus: reduction of micropollutants and of potentially pathogenic bacteria for further water quality improvement of the river Schussen, a tributary of Lake Constance, Germany [PDF]

, 2013
The project focuses on the efficiency of combined technologies to reduce the release of micropollutants and bacteria into surface waters via sewage treatment plants of different size and via stormwater overflow basins of different types. As a model river
Amler, Klaus, Blaha, Ludek, Gallert, Claudia, Giebner, Sabrina, Güde, Hans, Henneberg, Anja, Hess, Stefanie, Hetzenauer, Harald, Jedele, Klaus, Jung, Ralph-Michael, Kneipp, Sven, Krais, Stefanie, Kuch, Bertram, Köhler, Heinz-R., Lange, Claudia, Löffler, Herbert, Maier, Diana, Metzger, Jörg, Müller, Michael, Oehlmann, Jörg, Osterauer, Raphaela, Peschke, Katharina, Raizner, Jürgen, Rault, Magali, Rey, Peter, Richter, Doreen, Sacher, Frank, Scheurer, Marco, Schneider-Rapp, Jutta, Seifan, Merav, Spieth, Markus, Triebskorn, Rita, Vogel, Hans-Joachim, Weyhmüller, Michael, Winter, Josef, Wurm, Karl   +35 more
core   +1 more source

Novel multitarget-directed ligands (MTDLs) with acetylcholinesterase (AChE) inhibitory and serotonergic subtype 4 receptor (5-HT4R) agonist activities as potential agents against Alzheimer's disease: the design of donecopride.

Journal of Medicinal Chemistry, 2015
In this work, we describe the synthesis and in vitro evaluation of a novel series of multitarget-directed ligands (MTDL) displaying both nanomolar dual-binding site (DBS) acetylcholinesterase inhibitory effects and partial 5-HT4R agonist activity, among ...
Christophe Rochais, Cédric Lecoutey, F. Gaven, P. Giannoni, Katia Hamidouche, Damien Hédou, E. Dubost, D. Genest, S. Yahiaoui, T. Freret, V. Bouet, F. Dauphin, Jana Sopkova de Oliveira Santos, Céline Ballandonne, S. Corvaisier, A. Malzert‐Fréon, Rémi Legay, M. Boulouard, S. Claeysen, P. Dallemagne   +19 more
semanticscholar   +1 more source

Ethnomedicinal Uses, Phytochemistry, Pharmacological Activities, and Toxicology of the Subfamily Gomphrenoideae (Amaranthaceae): A Comprehensive Review

Chemistry &Biodiversity, EarlyView.
ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves, Giulia Cristina de Andreoli Souza, Alvaro Jose Hernandez Tasco, Marcos José Salvador   +3 more
wiley   +1 more source

Role of acetylcholinesterase in lung cancer

Thoracic Cancer, 2015
Acetylcholinesterase (AChE) plays a key role in catalytic hydrolysis of cholinergic neurotransmitters. Intensive research has proven the involvement of this protein in novel functions, such as cell adhesion, differentiation, and proliferation.
Huijun Xi, Ren-pei Wu, Jing-Jing Liu, Lingjuan Zhang, Zhaoshen Li   +4 more
semanticscholar   +1 more source

Chemical Characterization, Antioxidant, and Anticholinesterase Activities of Libidibia ferrea (Mart. Ex Tul.) L.P.Queiroz and In Silico Studies with the Acetylcholinesterase Enzyme

Chemistry &Biodiversity, EarlyView.
ABSTRACT Libidibia ferrea is used in many parts of Brazil for a variety of conditions, such as inflammation, respiratory disorders, muscle pain, and gastrointestinal problems. This study evaluated the chemistry and antioxidant and acetylcholinesterase (AChE) inhibitory activities of L. ferrea extracts. Hydroethanolic extracts of leaves (ELLF) and bark (
Lucas Soares Frota, Sara Ingrid Caetano Gomes Barbosa, Camila Costa Feitosa, Francisco Flávio da Silva Lopes, Daniel Pereira de Oliveira, Leonardo Soares Freitas, Adriano Lincoln Albuquerque Mattos, Wildson Max Barbosa da Silva, Hamilton Mitsugu Ishiki, Selene Maia de Morais   +9 more
wiley   +1 more source

A comparison of the distribution and morphology of ChAT-, VAChT-immunoreactive and AChE-positive neurons in the thoracolumbar and sacral spinal cord of the pig

Veterinární Medicína, 2008
Present knowledge concerning the organization of cholinergic structures of the spinal cord has been derived primarily from studies on small laboratory animals, while there is a complete lack of information concerning its structure in the pig.
J. Calka, M. Zalecki, K. Wasowicz, M.B. Arciszewski, M. Lakomy   +4 more
doaj   +1 more source