Results 151 to 160 of about 137,412 (311)

Functional validation of a white pupae minimal gene construct in Ceratitis capitata (Diptera: Tephritidae)

open access: yesInsect Science, EarlyView.
An intronless version of the white pupae (wp) gene was engineered to restore the wild type brown puparium color in white pupae phenotype mutants of the Mediterranean fruit fly, Ceratitis capitata. Functionality of the minimal gene version (mini‐wp) was verified in vivo, as one copy of mini‐wp successfully restored the wild type phenotype in homozygous ...
Lucas Henrique Figueiredo Prates   +4 more
wiley   +1 more source

DsiRNA‐mediated silencing of Ceratitis capitata transformer or transformer‐2 leads to masculinization of XX embryos and systemic gene silencing in ovaries

open access: yesInsect Science, EarlyView.
We carried out functional studies using Dicer‐substrate small interfering RNAs (DsiRNAs), targeting the sex determination genes Cctransformer (Cctra) and Cctransformer‐2 (Cctra‐2) in the Mediterranean fruit fly (Ceratitis capitata). Microinjection of DsiRNAs into XX embryos (0‐1 h old) rapidly triggered the expression of male‐specific Cctra isoforms ...
Gennaro Volpe   +20 more
wiley   +1 more source

Pharmacological and Mechanistic Interventions for Cognitive Impairment Associated With Schizophrenia: A Review of Registered Clinical Trials

open access: yesActa Psychiatrica Scandinavica, EarlyView.
ABSTRACT Background Schizophrenia is characterized by positive, negative, and cognitive symptoms. Current pharmacological treatments often fail to address cognitive deficits. In this review of clinical trials, we aim to identify studies that explore neurobiological (non‐psychological) strategies to address Cognitive Impairment Associated with ...
Bahareh Peyrovian   +3 more
wiley   +1 more source

ACETYLCHOLINESTERASE

open access: yesJournal of Biological Chemistry, 1950
Irwin B. Wilson, Felix. Bergmann
openaire   +2 more sources

Interventions to prevent postoperative neurocognitive complications: an umbrella review of meta‐analyses of randomised controlled trials

open access: yesAnaesthesia, EarlyView.
Summary Introduction The certainty of the effectiveness of interventions to manage postoperative neurocognitive complications remains unclear. The objective of this umbrella review was to synthesise and evaluate the evidence for interventions aimed at reducing the incidence of peri‐operative neurocognitive complications.
Filippo D'Amico   +7 more
wiley   +1 more source

Active anti-acetylcholinesterase component of secondary metabolites produced by the endophytic fungi of Huperzia serrata

open access: gold, 2015
Zhejian Wang   +6 more
openalex   +1 more source

Electrical Stimulation of Denervated Muscle: A Narrative Review

open access: yesArtificial Organs, EarlyView.
This review explores existing strategies for stimulating denervated muscle following lower motor neuron injury, including direct electrical stimulation of the muscle and artificial reinnervation to enable more comfortable and efficient indirect functional muscle stimulation.
Linshan Chu   +3 more
wiley   +1 more source

Acetylcholinesterase

open access: yesMolecular Pharmacology, 1972
Gabor Kato, Estrella Tan, James Yung
openaire   +2 more sources

The genome and stage‐specific transcriptomes of the carrot weevil, Listronotus oregonensis, reveal adaptive mechanisms for host specialisation and symbiotic interactions

open access: yesInsect Molecular Biology, EarlyView.
Comprehensive genome and stage‐specific transcriptomes reveal 14,637 genes in Listronotus oregonensis, advancing genetic insights into a key agricultural pest. Compared with related species, L. oregonensis exhibits reduced chemoreceptor gene families but expanded detoxification gene clusters, reflecting its narrow host range and adaptability.
Dave T. Ste‐Croix   +2 more
wiley   +1 more source

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