Results 171 to 180 of about 176,476 (335)

Bibliometric Analysis of Cubebenes and Related Sesquiterpenes: Natural Occurrence, Biosynthesis, Pharmacological Activities, and In‐Silico‐Based Future Therapeutic Potential

eFood, Volume 7, Issue 3, June 2026.
Cubebene‐related sesquiterpenes, found across diverse biological sources, exhibit promising pharmacological activities, including anti‐inflammatory, neuroprotective, and anticancer effects. This review highlights their molecular diversity, ADME profiles, and predicted multitarget interactions, underscoring their therapeutic relevance and potential in ...
Khadija Boualam, Ahmet B. Ortaakarsu, Sohaib Khatib, Mohamed A. Farag, Mansour Sobeh   +4 more
wiley   +1 more source

Mechanisms of carbamate resistance in the malaria vector: <i>Anopheles gambiae</i>. [PDF]

Parasite Epidemiol Control
Cleanclay WD, Akanni MH, Bajepade TI, Ajeoge JK, Zakari S.   +4 more
europepmc   +1 more source

Ivermectin Toxicity in Humans and Animals: Clinical Spectrum, Mechanisms, and Management

Journal of Applied Toxicology, Volume 46, Issue 6, Page 1856-1870, June 2026.
ABSTRACT Ivermectin is a widely used macrocyclic lactone with established efficacy against a broad range of parasitic infections in humans and animals and a long‐standing reputation for clinical safety. However, increasing evidence indicates that ivermectin can produce clinically relevant toxicity under specific conditions, particularly involving the ...
Serkan Yilmaz, Bayram Göktaş, İlker Ateş, Mustafa Çelik   +3 more
wiley   +1 more source

Conformationally locked 7-aryl tetrahydroisoquinolines as dual acetylcholinesterase inhibitors and antioxidants: role of intramolecular hydrogen bonding and aryl electronics. [PDF]

Front Pharmacol
Ríos V, Linares-Pipón C, Maulén C, Castro-Álvarez A, Bradshaw B, Romero-Parra J, Cuellar MA, Martínez-Cifuentes M, Parra C.   +8 more
europepmc   +1 more source

[The fasciculin-acetylcholinesterase interaction].

Journal de la Societe de biologie, 1999
Acetylcholinesterase (AChE) terminates the action of the neurotransmitter acetylcholine at cholinergic synapses in the central and peripheral nervous systems. Fasciculins, which belong to the family of “three-fingered” snake toxins, selectively inhibit mammalian AChEs with Ki values in the picomolar range.
openaire   +3 more sources

Comorbidities and Treatment Patterns in People With Myasthenia Gravis in Denmark, Finland and Sweden: A Population‐Based Observational Study

Muscle &Nerve, Volume 73, Issue 6, Page 1044-1057, June 2026.
ABSTRACT Introduction/Aims Comorbidities are frequent in myasthenia gravis (MG) and may affect treatment choices. Conversely, MG treatments may impact the risk of comorbidity. Our objective was to examine comorbidity and MG treatment patterns in nationwide MG cohorts in Denmark, Finland, and Sweden. Methods We included individuals with ≥ 2 MG diagnoses
Sari Atula, Fredrik Piehl, Ingrid Schager, Fredrik Berggren, Karin Humle, Mari Savolainen, Didier Pitsi, Juha Mehtälä, Aino Vesikansa, Riina‐Minna Väänänen, Tero Ylisaukko‐oja, John Vissing   +11 more
wiley   +1 more source

The importance of longitudinal evaluation using DAT‐SPECT in organophosphate‐induced toxic parkinsonism

Psychiatry and Clinical Neurosciences Reports, Volume 5, Issue 2, June 2026.
We performed longitudinal evaluation using magnetic resonance imaging (MRI) and dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) in a case of organophosphate‐induced toxic parkinsonism. Fluid‐attenuated inversion recovery (FLAIR) images showed bilateral striatal hyperintensity in the acute phase, followed by reduction of ...
Shuhei Nakao, Yoichiro Kogoh, Hideki Funahashi, Yusei Yanoma, Minako Azuma, Yasushi Ishida, Yoji Hirano   +6 more
wiley   +1 more source

Species-Specific Metabolite Profiles and Biological Activities of Bulgarian <i>Thymus</i> Species from Section <i>Hyphodromi</i>. [PDF]

Plants (Basel)
Kancheva D, Nikolova M, Georgiev V, Georgiev B, Yankova-Tsvetkova E, Aneva I.   +5 more
europepmc   +1 more source

Structure of the G119S Mutant Acetylcholinesterase of the Malaria Vector Anopheles gambiae Reveals Basis of Insecticide Resistance.

Structure, 2018
J. Cheung, A. Mahmood, R. Kalathur, Lixuan Liu, P. Carlier   +4 more
semanticscholar   +1 more source

Implementation of an Integrated Pharmacology Curriculum in a Flipped, Small‐Group, Case‐Based, Pre‐Clerkship Medical Curriculum Improved Student Performance

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT Rush Medical College implemented a new, integrated pre‐clerkship curriculum. Pharmacology was integrated with other basic sciences into a flipped, small‐group, case‐based structure. This report describes the main features of the pharmacology curriculum for pharmacology directors to have a template.
Brinda Desai Bradaric, Eric Van Rite, Lalita Prasad‐Reddy, Michael Bradaric   +3 more
wiley   +1 more source