The 80% ethanolic extract of Stachys germanica L. exhibited a phenolic‐rich phytochemical profile characterized by chlorogenic acid, naringin, luteolin, and kaempferol. The extract demonstrated notable antioxidant capacity, selective tyrosinase and α‐glucosidase inhibition, and significant antibacterial activity against Acinetobacter baumannii ATCC ...
Gözde Gülin İnan +8 more
wiley +1 more source
Deciphering the mechanisms underlying the dual-target inhibition of carbohydrate-digesting and neurodegenerative enzymes by Syzygium aromaticum (L.) Merr. & L.M. via molecular docking and dynamics simulations. [PDF]
Ojo OA +8 more
europepmc +1 more source
Potent Therapeutic Insights From Eryngium campestre: Phytochemical Profiling and In Vitro Evaluation
The phytochemical profiles and biological activity of ethyl acetate, ethanol, ethanol‐water, and water extracts of Eryngium campestre were assessed. E. campestre is a prospective source of multifunctional bioactive chemicals for food and nutraceutical uses, as demonstrated by the extracts' potential antioxidant, enzyme‐inhibitory, anticancer ...
Kübra Seyhan +12 more
wiley +1 more source
Eco-friendly-synthesized chitosan-zinc oxide-selenium nanocomposites: characterization and insecticidal activity. [PDF]
Selim TA +3 more
europepmc +1 more source
Abstract Background To observe the changes of butyrylcholinesterase (BChE) and heparin binding protein (HBP) in post‐traumatic inflammation, in order to determine whether they can be used as early diagnostic indicators of post‐traumatic inflammation. Methods Injury severity score (ISS) was used to evaluate the severity of trauma.
Huiying Zhang, Hui Liu, Jianguo Wang
wiley +1 more source
LC-HESI-MS/MS Profiling and Evaluation of Antioxidant, Anti-Inflammatory, Anti-α-Amylase, and Anti-Acetylcholinesterase Activities of Rhus tripartitum L. Leaf Extract: In Vitro and In Silico Studies. [PDF]
Ameur RB +7 more
europepmc +1 more source
Overall workflow of the study, from computational toxicology screening and FAERS‐based data mining to mechanistic prediction of neurotoxicity of irinotecan. ABSTRACT Irinotecan is a key chemotherapeutic agent, but its neurotoxicity limits its utility.
Cheng Shen +4 more
wiley +1 more source
Environmental toxicants may disrupt developmental pathways via strong molecular docking interactions with hub FGF proteins (FGF9 and FGF4) like dibenzo‐p‐dioxin (−7.2 kcal/mol) at the ASN146 residue of FGF9, driving congenital malformations as revealed by PPI networks and toxicity profiling.
Adarsh Kumar Shukla +3 more
wiley +1 more source
Plant-derived bioactive nutraceuticals mitigate aluminum-mediated neurotoxicity: Elucidated mechanisms and prospects. [PDF]
Atanda OE +4 more
europepmc +1 more source
Review of nutrition management of pediatric intestinal pseudo‐obstruction
Abstract Chronic intestinal pseudo‐obstruction (CIPO) is a rare, heterogeneous, and debilitating disorder characterized by profound intestinal dysmotility and severe nutrition challenges. Its presentation resembles that of mechanical bowel obstruction, but CIPO occurs in the absence of luminal obstruction.
Senthilkumar Sankararaman +5 more
wiley +1 more source

