Results 181 to 190 of about 85,087 (299)

Impact of Corn Oil on Biochemical and Neurochemical Markers in an Animal Model of Alzheimer's Disease. [PDF]

Neurol Int
Silva JR, Oliveira MEF, Campos LKP, Jacinto MJ, Souza AO.   +4 more
europepmc   +1 more source

Design, Synthesis and Molecular Docking Studies of Some Novel Hydrazone Derivatives Based on Trimetazidine as Selective and Potent AChE Inhibitors

Drug Development Research, Volume 87, Issue 7, November 2026.
ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative disease, and cholinergic dysfunction is considered one of the fundamental pathological factors of this disease. Guided by the clinically used acetylcholinesterase (AChE) inhibitor donepezil, we explored trimetazidine dihydrochloride as an accessible starting scaffold to generate ...
Muhammed Oğuzhan Doğan, Begüm Nurpelin Sağlık Özkan, Abdullah Burak Karaduman, Sevgi Karakuş, Yusuf Özkay, Zafer Asım Kaplancıklı, Fatih Tok   +6 more
wiley   +1 more source

Statement of Retraction: Novel Sunifiram carbamate hybrids as potential dual acetylcholinesterase inhibitor and NMDAR co-agonist simulation-guided analogue design and pharmacological screening. [PDF]

J Enzyme Inhib Med Chem
europepmc   +1 more source

EPN (<i>O</i>-ethyl-<i>O</i>-(4-nitrophenyl)-phenylthiophosphonate): MAK Value Documentation, addendum - Translation of the German version from 2024. [PDF]

MAK Collect Occup Health Saf
Hartwig A, MAK Commission.
europepmc   +1 more source

Evaluation of DNA/Chromosome Integrity and Cell Death in Human Metabolically Noncompetent and Competent Cells Exposed to N′‐(3,5‐Difluorobenzylidene)Pyridine‐4‐Carbohydrazide

Journal of Applied Toxicology, Volume 46, Issue 11, Page 4076-4084, November 2026.
ABSTRACT The N‐acylhydrazone scaffold is recognized as a privileged structure for the design of bioactive substances with increasing applications in medicinal chemistry research. Ensuring the safety of newly developed molecules is a critical step for both human health and environmental protection. Accordingly, this study aimed to evaluate the cytotoxic
Larissa Ribeiro Canuto Santos, Jéssica Natalia Barbosa de Almeida, Camila Cavalleiro Frias, Wanda Pereira Almeida, Edson Luis Maistro   +4 more
wiley   +1 more source

Mevinphos: MAK Value Documentation, addendum - Translation of the German version from 2024. [PDF]

MAK Collect Occup Health Saf
Hartwig A, MAK Commission.
europepmc   +1 more source

Acetylcholinesterase

, 2003
Jewess, P. J.
core  

Thyroid Dysfunction and Cognitive Impairment: Neural Mechanisms and Neurofeedback‐Based Interventions

Brain and Behavior, Volume 16, Issue 10, October 2026.
This graphical abstract illustrates the Thyroid‐Brain‐Cognition model, summarizing the multi‐level mechanisms linking thyroid dysfunction to cognitive impairment, and emphasizes neurofeedback as a non‐invasive intervention targeting brain network modulation and neuroplasticity enhancement.
Zhiqiang Ma, Yutong Liu, Mengyuan Chen, Mengyang Wang, Tao Liu   +4 more
wiley   +1 more source

Fenthion: MAK Value Documentation, addendum - Translation of the German version from 2024. [PDF]

MAK Collect Occup Health Saf
Hartwig A, MAK Commission.
europepmc   +1 more source

Aphicidal Potential and Metabolomic Profiling of Floriculture Leaf Waste Extracts Against Aphis craccivora Koch Under Laboratory Conditions

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
We utilized the leaf wastes of floriculture crops, namely Tagetes patula, Chrysanthemum grandiflorum, and Alstroemeria hybrida to determine their insecticidal potential against nymphs and adults of Aphis craccivora. Targeted and nontargeted metabolomics of extracts showed the presence of phenols and flavonoids, which corroborates the insecticidal ...
Aditya Singh Ranout, Rahul Kumar, Rupinder Kaur, Anish Kaachra, Anil Kumar, Dinesh Kumar, Bhavya Bhargava, Gireesh Nadda   +7 more
wiley   +1 more source