Results 161 to 170 of about 67,911 (287)

Evaluation of the pollution pressures posed by groups of chemicals on British riverine invertebrate populations

Biological Reviews, Volume 101, Issue 1, Page 106-127, February 2026.
ABSTRACT Globally, rivers receive a diverse range of chemicals, including metals, pesticides, persistent organic pollutants, petrochemicals, human and veterinary pharmaceuticals and personal care products. However, the extent to which these different chemical groups affect riverine invertebrate communities is not well defined.
Imogen P. Poyntz‐Wright, Xavier A. Harrison, Charles R. Tyler   +2 more
wiley   +1 more source

McCollough and Watercolor Effects: Visual Illusions that Fade in Early Alzheimer's Disease. [PDF]

Med Sci Monit
Sutnikiene V, Pakulaite-Kazliene G, Audronyte E, Kuzmickaite J, Kaubrys G.   +4 more
europepmc   +1 more source

Charakterisierung der N‐Methyltransferase SgPsmC: Anwendung in der kinetischen Racematspaltung von Pyrroloindolinen

Angewandte Chemie, Volume 138, Issue 2, 9 January 2026.
Die N‐Methyltransferase SgPsmC wurde charakterisiert und für die kinetische Racematspaltung von Pyrroloindolinen verwendet. Die Substitution an 3a‐Position erwies sich als eine Hauptdeterminante für die Enantioselektivität des Enzyms. Die Reaktion wurde mit einer Methionin‐Adenosyl‐Transferase gekoppelt, um S‐Adenosylmethionin in situ zu erzeugen und ...
Benjamin Panagiotis Chapple, Lia Nitz, Pascal Schneider, Birgit Henßen, Sebastian Myllek, Mona Haase, Thomas Classen, Jörg Pietruszka   +7 more
wiley   +1 more source

Evaluation of a New Methylimidazole‐Containing Thiosemicarbazone as a Cu+/Cu2+‐Targeting Ligand in the Context of Alzheimer's Disease

Chemistry – A European Journal, Volume 32, Issue 1, 2 January 2026.
HXE modulates Cu(Aβ) interaction, reducing ROS production and shifting peptide aggregation in the presence of Cu from toxic amorphous aggregates to less harmful fibrillar structures. These findings highlight HXE potential to interfere with Cu‐induced oxidative stress and aggregation pathways relevant to AD.
Barbara Marinho Barbosa, Charlène Esmieu, Antal Galvácsi, Mariana Viana Costa, Adèle Brison, Sonia M. Ladeira, Jade de Oliveira, Csilla Kállay, Christelle Hureau, Nicolás A. Rey   +9 more
wiley   +1 more source

Integrated Colorisensing Platform with Microneedles and Metal-Phenol Nanozymes for Point-of-Care Testings of Acetylcholinesterase Activity and Its Drug Inhibitor. [PDF]

Int J Nanomedicine
Chen E, Chang P, Xu H, Xu H, Zhu Z, Shen D.   +5 more
europepmc   +1 more source

T1WI‐SWI Dual Modal Magnetic Resonance Nanoprobes for Accurate Diagnosis of Early Stage Alzheimer's Disease

Advanced Science, Volume 13, Issue 1, 5 January 2026.
We developed a smart MRI nanoprobe targeting BACE1 and Aβ plaques. It crosses the blood‐brain barrier. Upon encountering BACE1, the probe is cleaved, enabling T1WI imaging detection. Subsequent reaction with ONOO− induces probe aggregation, enhancing magnetic susceptibility for sensitive SWI imaging of Aβ plaques.
Minghua Li, Aijun Shen, Xiaolong Gao, Chao Lin, Zongliang Huang, Qi Lv, Junjun Tang, Xiaolong Ma, Jiong Ni, Ju Tian, Jiaqi Wu, Xiaowen Xu, Wei Wang, Peijun Wang   +13 more
wiley   +1 more source

Dual inhibition of acetylcholinesterase and β-secretase by metabolites from <i>Echinocactus grusonii</i> Hildm.: <i>in silico</i> and <i>in vitro</i> investigations. [PDF]

RSC Adv
Heraiz AA, Othman A, Sayed AM, Hegazy MM, Mohammed AEI, Elhela AA.   +5 more
europepmc   +1 more source

Enzyme Immobilization by Hydrogen‐Bonded Organic Framework for the Construction of Plant‐Wearable Sensor

Advanced Science, Volume 13, Issue 3, 14 January 2026.
By modulating the charge of acetylcholinesterase, it is encapsulated within HOF materials, thereby enhancing its stability and maintaining its activity. Subsequently, the composite material is embedded in a glycerol‐sodium alginate gel, achieving the long‐term monitoring of pesticides.
Hongxia Li, Xiangyu Liu, Changshun Su, Xiaoguang Zhang, Chunyan Sun, Xu Yan   +5 more
wiley   +1 more source

Protective effect of Auraptene, a novel acetylcholinesterase inhibitor, on hydrogen peroxide-induced cell toxicity in PC12 cells

Elham Hadipour, Mahdi Khodadadi, Seyed Ahmad Emami, Samaneh Rahamouz-Haghighi, Elham Ramazani, Zahra Tayarani‐Najaran   +5 more
openalex   +2 more sources

Inhibitors of Monoamine Oxidase and Acetylcholinesterase as a Front Runner in CNS Drug Discovery

, 2020
Bijo Mathew, Hoon Kim
openalex   +1 more source