Results 211 to 220 of about 176,114 (393)

The fast‐dissociating D2 antagonist antipsychotic JNJ‐37822681 is a neuronal Kv7 channel opener: Potential repurposing for epilepsy treatment

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Pharmacological activation of neuronal M‐current mediated by Kv7 (Kv7.2–5) potassium channels is a validated mechanism for epilepsy treatment. However, since the market withdrawal of the prototype Kv7 activator retigabine, no Kv7 activator is clinically available for this condition.
Lidia Carotenuto   +16 more
wiley   +1 more source

Hyperhidrosis: don't sweat it

open access: yesInternal Medicine Journal, EarlyView.
Abstract Hyperhidrosis is an under‐reported and under‐treated condition that causes significant patient morbidity. Secondary causes require consideration, but the vast majority of cases are idiopathic. The condition is encountered by a range of clinicians, including neurologists, dermatologists and endocrinologists, and it pays to be familiar with the ...
Mitchell J. Lycett, Karl Ng
wiley   +1 more source

Computer-aided discovery of dual-target compounds for Alzheimer's from ayurvedic medicinal plants. [PDF]

open access: yesPLoS One
Shah M   +10 more
europepmc   +1 more source

Structural Bioinformatics Applied to Acetylcholinesterase Enzyme Inhibition. [PDF]

open access: yesInt J Mol Sci
Reynoso-García MF   +3 more
europepmc   +1 more source

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