An intramolecular Mannich reaction (A/B/E/F rings) and intermolecular Diels–Alder reactions (C/D rings) afforded a cage‐like hexacyclic core skeleton of denudatine alkaloids. Derivatization of the hexacyclic intermediate enabled the first asymmetric total syntheses of four denudatine alkaloids: (–)‐cochlearenine, (–)‐macrocentrine, (–)‐dictizine, and (–
Shun Kawano +5 more
wiley +2 more sources
Dual inhibition of acetylcholinesterase and β-secretase by metabolites from <i>Echinocactus grusonii</i> Hildm.: <i>in silico</i> and <i>in vitro</i> investigations. [PDF]
Heraiz AA +5 more
europepmc +1 more source
Metal‐organic framework–hydrogel composites are explored as multifunctional materials for next‐generation sensors and sensing systems. This review summarizes recent advances in employing these smart composites to fabricate optical, electrochemical, and electromechanical sensors, emphasizing their potential in healthcare, biomedical diagnostics ...
Md Sazzadur Rahman +2 more
wiley +1 more source
Biological Flora of Britain and Ireland: Geranium sylvaticum*
Geranium sylvaticum is a perennial forb of upland grasslands, woodlands and riverbanks in northern Britain, with scattered native occurrences also in Wales, central England and Northern Ireland. It has an extensive native range in Europe and Asia. The species is gynodioecious, with individual plants typically female or hermaphrodite.
Markus Wagner +6 more
wiley +1 more source
Polymorphism in the acetylcholinesterase gene of Musca domestica L. field populations in Turkey [PDF]
Sibel Başkurt +3 more
openalex +1 more source
Studies on the rare of central catecholaminergic mechanisms in the antidotal effect of the oxime HI 6 in soman poisoned mice [PDF]
Arbogast, Helmut +3 more
core
ABSTRACT Globally, rivers receive a diverse range of chemicals, including metals, pesticides, persistent organic pollutants, petrochemicals, human and veterinary pharmaceuticals and personal care products. However, the extent to which these different chemical groups affect riverine invertebrate communities is not well defined.
Imogen P. Poyntz‐Wright +2 more
wiley +1 more source
Kinetic analysis suggests that malathion at low environmental exposures is not toxic to humans. [PDF]
Schopfer LM +3 more
europepmc +1 more source
Microplastic Pollution in Aquaculture: Challenges and Mitigation
ABSTRACT Microplastics (MPs) have gained significant attention due to their potential environmental threat. This paper addresses MPs contamination in aquaculture, a critical concern for food safety and public health. The extensive use and disposal of plastic products in aquaculture, like netting materials, pose a significant threat to aquatic life ...
Sivakamavalli Jeyachandran +5 more
wiley +1 more source
Design, synthesis and evaluation of new pyrazino[1',2':1,5]pyrrolo[2,3-<i>d</i>]pyrimidines as tacrine-like acetylcholinesterase inhibitors. [PDF]
Muzychka LV +4 more
europepmc +1 more source

