Results 221 to 230 of about 176,114 (393)
Documented Patient Values and Preferences and Attendance at Goals of Care Conversations. AD/ADRD—Alzheimer's disease and related dementias. ABSTRACT Background Goals of care (GOC) conversations are an evidence‐based practice that help clarify and align patient values and preferences for medical care with treatment options.
Gina Piscitello+5 more
wiley +1 more source
Discovery of Novel Anti-Acetylcholinesterase Peptides Using a Machine Learning and Molecular Docking Approach. [PDF]
Xiao W, Chen LZ, Chang J, Xiao YW.
europepmc +1 more source
Effect of pH on inhibition and spontaneous reactivation of acetylcholinesterase treated with esters of phosphorus acids and of carbamic acids [PDF]
openalex +1 more source
ABSTRACT Background Several amyloid targeting therapies have been approved for Alzheimer's disease (AD), including lecanemab (Leqembi). However, real‐world implementation of these drugs has uncovered significant challenges. Methods We conducted a national cross‐sectional survey of healthcare professionals from multiple disciplines participating in the ...
Alison J. O'Donnell+5 more
wiley +1 more source
First Insights Into the LC‐HRMS Profiling and Biological Activities of Crocus graveolens [PDF]
This study reports the first comprehensive analysis of Crocus graveolens Boiss. & Reut. using LC‐HRMS, identifying 33 secondary metabolites, with rutin as the major compound (162.808 ± 4.5 μg/g extract). The extract showed moderate antioxidant activity and effectively inhibited acetylcholinesterase (30.88% ± 1.51%) and butyrylcholinesterase (61.22% ± 0.
Ersoy E+5 more
europepmc +2 more sources
ABSTRACT Background Depressive symptoms are common in caregivers of people with dementia, with most interventions targeting their emotional/cognitive stance. Unknown is whether targeting people with dementia's quality of life can improve caregiver mood.
Laura N. Gitlin+2 more
wiley +1 more source
Multifaceted Biological Activity of Rutin, Quercetin, and Quercetin's Glucosides. [PDF]
Zielińska D+3 more
europepmc +1 more source
Summary Dreaming, a common yet mysterious cognitive phenomenon, is an involuntary process experienced by individuals during sleep. Although the fascination with dreams dates back to ancient times and gained therapeutic significance through psychoanalysis in the early twentieth century, its scientific investigation only gained momentum with the ...
Carlotta Mutti+2 more
wiley +1 more source
Acetylcholinesterase-like proteins are a major component of reproductive trail mucus in the invasive pest land snail, Theba pisana. [PDF]
Lutschini IRT+3 more
europepmc +1 more source
ABSTRACT Parasomnias are abnormal behaviours or mental experiences during sleep or the sleep–wake transition. As disorders of arousal (DOA) or REM sleep behaviour disorder (RBD) can be difficult to capture in the sleep laboratory and may need to be diagnosed in large communities, new home diagnostic devices are being developed, including actigraphy ...
Claudia Picard‐Deland+5 more
wiley +1 more source