Results 121 to 130 of about 3,306 (206)

DIETARY SUPPLEMENTS INFLUENCE ACTIVITY OF ACID-SENSING ION CHANNELS

, 2014
Dietary supplements or nutraceutical industry contributes billions of dollars to Unites States economy every year. The dietary supplement we intend to study is one of the most commonly used nutraceutical available in the market over the counter.
Agharkar, Amruta S., Gonzales, Eric B.
core  

Acid-sensing ion channel (ASIC) 4 predominantly localizes to an early endosome-related organelle upon heterologous expression. [PDF]

Sci Rep, 2015
Schwartz V, Friedrich K, Polleichtner G, Gründer S.   +3 more
europepmc   +1 more source

Genetic exploration of roles of acid‐sensing ion channel subtypes in neurosensory mechanotransduction including proprioception

Although acid‐sensing ion channels (ASICs) are proton‐gated ion channels responsible for sensing tissue acidosis, accumulating evidence has shown that ASICs are also involved in neurosensory mechanotransduction. However, in contrast to Piezo ion channels,
Cheng‐Han Lee, Chih‐Cheng Chen, Jia‐Ying Sung, Yi‐Chen Lin   +3 more
core   +1 more source

Acid-sensing ion channel modulation by nonproton ligands: the influence of divalent cations

, 2015
1. The acid-sensing ion channel (ASIC) is emerging as a potential mediator for a variety of pathologies, such as stroke, pain, and mental health diseases.
Smith, Rachel N., Gonzales, Eric B.
core  

Determinants of ion selectivity in ASIC1a- and ASIC2a-containing acid-sensing ion channels

, 2020
Trimeric acid-sensing ion channels (ASICs) contribute to neuronal signaling by converting extracellular acidification into excitatory sodium currents. Previous work with homomeric ASIC1a implicates conserved leucine (L7') and consecutive glycine-alanine ...
Celine Boiteux (19984008), Toby Allen (18031645), Stephan Pless (20054355), Zeshan Sheikh (20066598), Timothy Lynagh (1434412), Emelie Flood (5742350)   +5 more
core  

Acid-sensing ion channel 2a assembles with epithelial Na⁺ channel β and γ subunits to form mechanosensitive ion channels. [PDF]

J Biol Chem
Shi S, Whelan SCM, Szekely KG, Kashlan OB, Drummond H, Kleyman TR.   +5 more
europepmc   +1 more source

Acid-sensing ion channels and their role in controlling pain in the post-operative stage. [PDF]

Int J Physiol Pathophysiol Pharmacol
Warikoo G, Sun A, Chu XP.
europepmc   +1 more source

Acid-sensing ion channel (ASIC) 1a/2a heteromers have a flexible 2:1/1:2 stoichiometry. [PDF]

Proc Natl Acad Sci U S A, 2014
Bartoi T, Augustinowski K, Polleichtner G, Gründer S, Ulbrich MH.   +4 more
europepmc   +1 more source

Acid-sensing (proton-gated) ion channels (ASICs)

British Journal of Pharmacology, 2009
openaire   +2 more sources

Zinc Permeation Through Acid-Sensing Ion Channels. [PDF]

Cells
Chu XP, Inoue K, Xiong ZG.
europepmc   +1 more source