NOVEL GABAA-RHO1 INTERACTIONS WITH ACID SENSING ION CHANNEL LIGANDS
γ- amino butyric acid (GABA) is the major inhibitory neurotransmitter in the vertebrate brain, and targets the ionotropic GABAA receptors. GABAC, or GABAA-rho, is a subclass of GABAA receptors located in the retina.
Snell, Heather D., Gonzales, Eric B.
core
[Corrigendum] Inhibition of acid‑sensing ion channel 1a attenuates acid‑induced activation of autophagy via a calcium signaling pathway in articular chondrocytes. [PDF]
Gao WF, Xu YY, Ge JF, Chen FH.
europepmc +1 more source
Beyond sodium channel blockade: Flavonoid as alternative local anesthetic candidates of lidocaine. [PDF]
Takeda M, Utugi S, Toyota R, Sashide Y.
europepmc +1 more source
ROLES OF ACID-SENSING ION CHANNELS (ASICS) IN PERIPHERAL NEUROPEPTIDE SECRETION AND PAIN
Acid-sensing ion channels (ASICs) are non-voltage-gated sodium channels activated by an extracellular acidification. They are widely expressed in neurons of the central and peripheral nervous system. ASICs have a role in learning, the expression of fear, in neuronal death after cerebral ischemia, and in pain sensation.
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Proton-activated chloride channel PACC1 as acid sensor in epidermal desquamation. [PDF]
Xia K +15 more
europepmc +1 more source
Simulated Microgravity Causes Delayed Platelet Activation and Downregulates Acid-Sensing Ion Channel 1/2 Protein Expression. [PDF]
Bala N +4 more
europepmc +1 more source
Lipid Regulation of Mechanosensitive Ion Channels. [PDF]
Cai Y, Bauer C, Shi J.
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Identification of acid-sensing ion channels (ASICS) in bone
Jahr, H +5 more
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Joint Acidosis and Acid-Sensing Receptors and Ion Channels in Osteoarthritis Pathobiology and Therapy. [PDF]
Martin WN +8 more
europepmc +1 more source
High ASIC3 Expression Correlates with Poor Prognosis in Lung Cancer Patients and Mediates Hypercapnic Acidosis-Induced EMT in A549 Cells. [PDF]
Zhao L +6 more
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