Results 141 to 150 of about 8,571 (202)

Acid ceramidase ASAH1 is a key regulator of epidermal ceramide levels and composition. [PDF]

J Biol Chem
Nobumoto W, Naganuma T, Nozaka N, Ohno Y, Nojiri K, Kihara A.   +5 more
europepmc   +1 more source

Acid ceramidase expression and biomarker potential in patients with locally advanced rectal cancer. [PDF]

Biomol Biomed
Bjelanovic J, Zeljic K, Miladinov M, Barisic G, Dragicevic S.   +4 more
europepmc   +1 more source

Acid ceramidase inhibition enhances BCL-2 targeting in venetoclax-resistant acute myeloid leukemia. [PDF]

Blood Neoplasia
Ung J, Tan SF, Shaw JJP, Taori M, Deddens TM, Venancio G, Montgomery MM, Hagen JT, Aruleba RT, Golla UR, Sharma A, Paudel BB, Lee I, Ramamoorthy B, Janes KA, Garrett-Bakelman F, Cabot MC, Fisher-Wellman KH, Fox TE, Claxton DF, Chalfant CE, Feith DJ, Loughran TP.   +22 more
europepmc   +1 more source

Regulation of exosome release by lysosomal acid ceramidase in coronary arterial endothelial cells: Role of TRPML1 channel. [PDF]

Curr Top Membr, 2022
Li G, Huang D, Li P, Yuan X, Yarotskyy V, Li PL.   +5 more
europepmc   +1 more source

Acid ceramidase regulates CD8+ T-cell exhaustion via type I interferon-mediated upregulation of PD-L1. [PDF]

Front Immunol
Hu Z, Abdelrahman H, Elwy A, Kuang F, Dhiman S, Ali S, Marson M, Holnsteiner L, Hamdan TA, Friebus-Kardash J, Wiebeck E, Hansen W, Scheu S, Gulbins E, Lang PA, Lang KS, Lang J.   +16 more
europepmc   +1 more source

Inhibition of acid ceramidase elicits mitochondrial dysfunction and oxidative stress in pancreatic cancer cells. [PDF]

Cancer Sci, 2021
Taniai T, Shirai Y, Shimada Y, Hamura R, Yanagaki M, Takada N, Horiuchi T, Haruki K, Furukawa K, Uwagawa T, Tsuboi K, Okamoto Y, Shimada S, Tanaka S, Ohashi T, Ikegami T.   +15 more
europepmc   +1 more source

Inhibition or genetic reduction of ASAH1/acid ceramidase restore α-synuclein clearance in mutant GBA1 dopamine neurons from Parkinson's patients. [PDF]

Hum Mol Genet
Kumar M, Feldman RA.
europepmc   +1 more source

Exploration of a Class of Aryl Imidazolyl Ureas As Potent Acid Ceramidase Inhibitors for the Treatment of Fibrotic Diseases. [PDF]

ACS Omega
Beresis R, Prathigudupu V, Cable C, Yu A, Adler M, Ramamoorthi R, Yeon SK, Gordan JD, Sharma S, DeGrado WF, Zaro B, Chen JY, Jo H.   +12 more
europepmc   +1 more source

Cardiac dysfunction and altered gene expression in acid ceramidase-deficient mice. [PDF]

Am J Physiol Heart Circ Physiol
Kleynerman A, Rybova J, McKillop WM, Dlugi TA, Faber ML, Fuller M, O'Meara CC, Medin JA.   +7 more
europepmc   +1 more source

Publisher Correction: Acid ceramidase controls apoptosis and increases autophagy in human melanoma cells treated with doxorubicin. [PDF]

Sci Rep, 2021
Lai M, Amato R, La Rocca V, Bilgin M, Freer G, Spezia P, Quaranta P, Piomelli D, Pistello M.   +8 more
europepmc   +1 more source