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Targeting Acid-Sensing Ion Channels in Disease
Acidosis is a central feature of many pathological conditions, and while the activity of many ion channels is suppressed under acidic conditions, acid-sensing ion channels (ASICs) are exquisitely sensitive to decreases in pH and activated by protons. The expression and function of ASICs is enhanced under conditions of ischemia, inflammation, and trauma.Senescall, Victor +9 more
openaire +2 more sources
Acid‐sensing ion channels in allergic rhinitis
Clinical & Experimental Allergy, 2012openaire +3 more sources
Acid-sensing ion channels in healthy and degenerated human intervertebral disc
Connective Tissue Research, 2014MIGUEL Del Valle +2 more
exaly
Philosophical Transactions of the Royal Society B: Biological Sciences, 2016
Oleksandr Ievglevskyi +2 more
exaly
Oleksandr Ievglevskyi +2 more
exaly
Current perspectives on acid-sensing ion channels: new advances and therapeutic implications
Expert Review of Clinical Pharmacology, 2010Jacques Noel +2 more
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Acid-sensing ion channels: Linking extracellular acidification with atherosclerosis
Clinica Chimica Acta, 2020Xue-Jiao Xie, Hong-Feng Gu
exaly

