Results 1 to 10 of about 143,662 (295)

Targeting hypoxia regulated sodium driven bicarbonate transporters reduces triple negative breast cancer metastasis

open access: yesNeoplasia: An International Journal for Oncology Research, 2022
Regions of low oxygen (hypoxia) are found in >50% of breast tumours, most frequently in the more aggressive triple negative breast cancer subtype (TNBC). Metastasis is the cause of 90% of breast cancer patient deaths. Regions of tumour hypoxia tend to be
Christopher Paul Carroll   +8 more
doaj   +1 more source

Transcriptomic Response to Acidosis Reveals Its Contribution to Bone Metastasis in Breast Cancer Cells

open access: yesCells, 2022
Bone is the most common site of metastasis in breast cancer. Metastasis is promoted by acidosis, which is associated with osteoporosis. To investigate how acidosis could promote bone metastasis, we compared differentially expressed genes (DEGs) in MDA-MB-
Ana Sayuri Yamagata   +6 more
doaj   +1 more source

Survival with Good Neurological Outcome despite Prolonged Cardiopulmonary Resuscitation and Extreme Acidosis after Out-of-Hospital Cardiac Arrest Due to Acute Myocardial Infarction: A Case Report and Review of the Literature

open access: yesClinics and Practice, 2023
We report the case of a 49-year-old male who suffered from a myocardial infarction with subsequent cardiac arrest. The emergency medical team began cardiopulmonary resuscitation, including defibrillation of ventricular fibrillation.
Sylvère Störmann   +6 more
doaj   +1 more source

Clinical Phenotypes of Hypoxia in Patients with COVID-19

open access: yesОбщая реаниматология, 2021
The aim of the study was to examine the clinical phenotypes of hypoxia in patients with COVID-19 in relation to the severity of acute respiratory failure (ARF).Material and methods.
O. V. Voennov   +4 more
doaj   +1 more source

Evaluation of Megasphaera elsdenii supplementation on rumen fermentation, production performance, carcass traits and health of ruminants: a meta-analysis [PDF]

open access: yesAnimal Bioscience, 2023
Objective This study was conducted to evaluate the use of Megasphaera elsdenii (M. elsdenii) as a probiotic on rumen fermentation, production performance, carcass traits and health of ruminants by integrating data from various related studies using meta ...
Irwan Susanto   +5 more
doaj   +1 more source

Dose of Bicarbonate to Maintain Plasma pH During Maximal Ergometer Rowing and Consequence for Plasma Volume

open access: yesFrontiers in Physiology, 2022
Rowing performance may be enhanced by attenuated metabolic acidosis following bicarbonate (BIC) supplementation. This study evaluated the dose of BIC needed to eliminate the decrease in plasma pH during maximal ergometer rowing and assessed the ...
Henning Bay Nielsen   +3 more
doaj   +1 more source

Distal renal tubular acidosis as a cause of osteomalacia in a patient with primary Sjögren's syndrome [PDF]

open access: yesVojnosanitetski Pregled, 2005
Background. One half of the patients with primary Sjögren’s syndrome has extraglandular manifestations, including renal involvement. The most frequent renal lesion is tubulo-interstitial nephritis, which manifests clinically as distal tubular acidosis ...
Jovelić Aleksandra, Stefanović Dušan
doaj   +1 more source

[Lactic acidosis].

open access: yesMinerva medica, 1986
Lactic acidosis is a metabolic disturbance characterized by an increase of the production/clearance ratio of lactate. Lactate is a catabolite of glycolysis when this takes place under anaerobic conditions. Clinically LA is characterized by: signs of acidosis, venous blood lactate greater than 5 mMol/l, arterial pH less than 7.25.
MOLINATTI GM   +3 more
openaire   +5 more sources

Veno-arterial extracorporeal membrane oxygenation as a bridge to recovery in acute aluminium phosphide poisoning: A case report

open access: yesAsian Journal of Medical Sciences, 2022
Aluminium phosphide (AlP) is a common fumigant used for controlling rodents and pests in grain storage facilities. Its consumption is reported in accidental or suicidal cases carrying high mortality.
Arvind Kumar   +4 more
doaj   +1 more source

A mathematical model of the four cardinal acid-base disorders

open access: yesMathematical Biosciences and Engineering, 2020
Precise maintenance of acid-base homeostasis is fundamental for optimal functioning of physiological and cellular processes. The presence of an acid-base disturbance can affect clinical outcomes and is usually caused by an underlying disease.
Alhaji Cherif   +7 more
doaj   +1 more source

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