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New England Journal of Medicine, 2014 Lactic acidosis results from the accumulation of lactate and protons in the body fluids and is often associated with poor clinical outcomes. The effect of lactic acidosis is governed by its severity and the clinical context. Mortality is increased by a factor of nearly three when lactic acidosis accompanies low-flow states or sepsis,1 and the higher ...
Ingelfinger, Julie R +2 more
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Impact of high-energy diets on the rumen environment and digital cushion in confined cattle [PDF]
Pesquisa Veterinária Brasileira, 2020 : This study aimed to identify gross and microscopic changes, caused by high-energy diets, in the rumen environment and hoof of confined beef cattle. The study sample comprised 40 confined heifers (Bos taurus) with no disease history divided into four ...
Nicolas C. Tavares +7 more
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Frontiers in Physiology, 2022 Hitherto, the rabbit has long been known to have a very poor tolerance to non—volatile acid. In this study, we tested the hypothesis that acid resilience in the acidotic rabbit can be increased by enhancing the plasma availability of a naturally ...
Patrick A. Walsh
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Kidney International, 1999 In recent years there has been increasing evidence for the deleterious effect of acidosis on a number of fundamental systems of the body including nutrition [1, 2]. Approximately 70 mmol of hydrogen ions are produced daily by the body, and to maintain acid-base balance there must be an equivalent net acid secretion by the kidney.
Timothy H.J. Goodship +2 more
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Etiology and Management of Acute Metabolic Acidosis: An Update
Kidney & Blood Pressure Research, 2020 Background: The etiology of acute metabolic acidosis (aMA) is heterogeneous, and the consequences are potentially life-threatening. The aim of this article was to summarize the causes and management of aMA from a clinician’s perspective.
Igor Matyukhin +3 more
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Frontiers in Physiology, 2021 Aims: In contrast to cardiovascular disease, low rather than high ventilatory inefficiency, evaluated by the minute ventilation-carbon dioxide output (V'E-V'CO2)-slope, has been recognized as being related to greater disease severity in chronic ...
Keisuke Miki +9 more
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Journal of the American Medical Association, 1920 The subject of acidosis in nephritis is one of such practical importance that it deserves emphasis from a clinical standpoint. Many significant observations bearing on this general topic have accumulated during the last ten years. In the study of this question, Van Slyke's simple method 1 of determining the alkali reserve of the body with the aid of ...
Victor C. Myers, Arthur F. Chace
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Scientific Reports, 2020 Extracellular acidosis is considered as a hallmark of most human tumors, which plays an important role in promoting tumor malignant and aggressive phenotype in tumorigenesis. Acidosis and lactic acidosis can induce different responses in tumors. Previous
Jiayue Gao +8 more
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