Results 1 to 10 of about 125,758 (245)

Targeting hypoxia regulated sodium driven bicarbonate transporters reduces triple negative breast cancer metastasis

Neoplasia: An International Journal for Oncology Research, 2022
Regions of low oxygen (hypoxia) are found in >50% of breast tumours, most frequently in the more aggressive triple negative breast cancer subtype (TNBC). Metastasis is the cause of 90% of breast cancer patient deaths. Regions of tumour hypoxia tend to be
Christopher Paul Carroll, Hannah Bolland, Eric Vancauwenberghe, Pamela Collier, Alison A. Ritchie, Philip A. Clarke, Anna M. Grabowska, Adrian L Harris, Alan McIntyre   +8 more
doaj   +1 more source

Evaluation of Megasphaera elsdenii supplementation on rumen fermentation, production performance, carcass traits and health of ruminants: a meta-analysis [PDF]

Animal Bioscience, 2023
Objective This study was conducted to evaluate the use of Megasphaera elsdenii (M. elsdenii) as a probiotic on rumen fermentation, production performance, carcass traits and health of ruminants by integrating data from various related studies using meta ...
Irwan Susanto, Komang G. Wiryawan, Sri Suharti, Yuli Retnani, Rika Zahera, Anuraga Jayanegara   +5 more
doaj   +1 more source

Metabolic diseases in cattle

Ветеринария сегодня, 2021
The main trend in the development of dairy farming in the Russian Federation suggests maximising milk yield and reducing milk net cost. The economic effectiveness of industrial dairy farming is largely determined by adequate feeding, as well as effective
V. A. Mischenko, A. V. Mischenko, R. V. Yashin, V. A. Yevgrafova, T. B. Nikeshina   +4 more
doaj   +1 more source

Dose of Bicarbonate to Maintain Plasma pH During Maximal Ergometer Rowing and Consequence for Plasma Volume

Frontiers in Physiology, 2022
Rowing performance may be enhanced by attenuated metabolic acidosis following bicarbonate (BIC) supplementation. This study evaluated the dose of BIC needed to eliminate the decrease in plasma pH during maximal ergometer rowing and assessed the ...
Henning Bay Nielsen, Henning Bay Nielsen, Stefanos Volianitis, Niels H. Secher   +3 more
doaj   +1 more source

Clinical Characteristics of Patients with Methyl Alcohol Intoxication Followed up in the Intensive Care Unit and Factors Affecting Mortality

Bagcilar Medical Bulletin, 2023
Objective:Methyl alcohol is a solvent obtained by the fermentation of wood and used in various fields industrially. Due to its cheap and easy accessibility, it is frequently used to manufacture moonshine and can lead to severe morbidity and mortality ...
Kadir Arslan, Ayça Sultan Şahin
doaj   +1 more source

Veno-arterial extracorporeal membrane oxygenation as a bridge to recovery in acute aluminium phosphide poisoning: A case report

Asian Journal of Medical Sciences, 2022
Aluminium phosphide (AlP) is a common fumigant used for controlling rodents and pests in grain storage facilities. Its consumption is reported in accidental or suicidal cases carrying high mortality.
Arvind Kumar , Jai Prakash , Gaurav Arya, Anand Kumar Yadav , Aman Dhankar   +4 more
doaj   +1 more source

[Lactic acidosis].

Minerva medica, 1986
Lactic acidosis is a metabolic disturbance characterized by an increase of the production/clearance ratio of lactate. Lactate is a catabolite of glycolysis when this takes place under anaerobic conditions. Clinically LA is characterized by: signs of acidosis, venous blood lactate greater than 5 mMol/l, arterial pH less than 7.25.
MOLINATTI GM, PASSERA P., SCHIMENTI P., PORTA, Massimo   +3 more
openaire   +5 more sources

Aging exaggerates blood pressure response to ischemic rhythmic handgrip exercise in humans

Physiological Reports, 2021
Ischemic skeletal muscle conditions are known to augment exercise‐induced increases in blood pressure (BP). Aging is also a factor that enhances the pressor response to exercise.
Daisuke Hasegawa, Amane Hori, Yukiko Okamura, Reizo Baba, Kenichi Suijo, Masaki Mizuno, Jun Sugawara, Koji Kitatsuji, Hisayoshi Ogata, Kaoru Toda, Norio Hotta   +10 more
doaj   +1 more source

Base excess and pH as predictors of outcomes in secondary peritonitis in a resource limited setting - A prospective study

Journal of Clinical Sciences, 2020
Background: Estimation of the serum pH and base excess as determinants of the adequacy of resuscitation may predict the patient outcome in peritonitis. Materials, Patients and Methods: This was a prospective study conducted in University College Hospital,
O Oludolapo Afuwape, Omobolaji Ayandipo, Samuel Aroso   +2 more
doaj   +1 more source

HMG-CoA Lyase Deficiency: A Retrospective Study of 62 Saudi Patients

Frontiers in Genetics, 2022
3-Hydroxy-3-methylglutaryl-coenzyme A lyase deficiency (HMG-CoA lyase) is a rare inborn error of leucine degradation and ketone body synthesis, caused by homozygous or compound heterozygous disease-causing variants in HMGCL.
Majid Alfadhel, Majid Alfadhel, Basma Abadel, Hind Almaghthawi, Muhammad Umair, Zuhair Rahbeeni, Eissa Faqeih, Mohammed Almannai, Ali Alasmari, Mohammed Saleh, Wafaa Eyaid, Wafaa Eyaid, Ahmed Alfares, Ahmed Alfares, Fuad Al Mutairi, Fuad Al Mutairi   +15 more
doaj   +1 more source