Results 111 to 120 of about 64,694 (238)

Is there NO treatment for severe sepsis? [PDF]

open access: yes, 2008
Sepsis is a systemic inflammatory response syndrome in the presence of suspected or proven infection, and it may progress to or encompass organ failure (severe sepsis) and hypotension (septic shock).
Bredan, Amin, Cauwels, Anje
core   +2 more sources

Lactate and colic–Shetland ponies as an example of one size does not fit all

open access: yesEquine Veterinary Education, EarlyView.
Summary The clinical commentary discusses the utility of peritoneal lactate alone, and in the context of other clinical factors, in determining the presence of a strangulating intestinal obstruction. A current study on Shetland ponies has revealed that peritoneal lactate well outside the range typically to be considered at risk of strangulating ...
A. T. Blikslager
wiley   +1 more source

HIV-associated multi-centric Castleman’s disease with multiple organ failure: cuccessful treatment with rituximab [PDF]

open access: yes, 2010
Introduction: Multicentric Castleman's Disease (MCD), a lymphoproliferative disorder associated with Human Herpes Virus-8 (HHV-8) infection, is increasing in incidence amongst HIV patients.
Agarwal, B   +7 more
core  

Beyond the chaos: How architecture structures tumour biology

open access: yesThe FEBS Journal, EarlyView.
Tissue architecture shapes tumour initiation and progression through multiple interconnected layers continuously remodelled over time. This review outlines how physical forces, biochemical cues, cellular niches and systemic influences contribute to tumour evolution.
Lea Dörner   +3 more
wiley   +1 more source

The Treatment of Diabetic Acidosis [PDF]

open access: yes, 1966
The patient with diabetes mellitus who becomes unconscious presents a problem in differential diagnosis. We now recognize six possible causes of coma in the diabetic patient.
Danowski, Thaddeus S.
core   +1 more source

Lactic Acidosis in Asthma: Report of Two Cases and Review of the Literature

open access: yesCanadian Respiratory Journal, 2002
Lactic acidosis is commonly associated with states of hypoxia and decreased tissue perfusion. Elevated lactic acid levels have also been observed in individuals who are not septic and who are normotensive, but who have received systemic adrenergic ...
Suma Prakash, Sanjay Mehta
doaj   +1 more source

Effects of short‐term tofogliflozin treatment on the insulin secretory capacity of people with type 2 diabetes: A randomized controlled trial, the TOP‐ELM study

open access: yesJournal of Diabetes Investigation, EarlyView.
Tofogliflozin was compared with metformin in treatment‐naïve people with type 2 diabetes for 4 weeks. Overall insulin secretory capacity did not improve; however, tofogliflozin was associated with an improved disposition index in individuals with poorer baseline glucose tolerance or greater improvement after treatment.
Maiko Miyamoto   +39 more
wiley   +1 more source

Severe Type B Lactic Acidosis in a Rare and Aggressive HIV-Related Lymphoma

open access: yesCase Reports in Critical Care, 2019
We describe the prognostic implication and aggressive clinical course of lymphoma-related lactic acidosis in a rare HIV-related lymphoma. Patient was diagnosed with plasmablastic lymphoma and developed severe lactic acidosis, and was treated on the ...
John Harwood Scott   +4 more
doaj   +1 more source

Metformin-related acidosis in a woman while performing Haj: A conservative approach

open access: yesSaudi Journal of Kidney Diseases and Transplantation, 2015
Metformin is a first-line oral anti-hyperglycemic agent. It decreases insulin resistance, decreases hepatic glucose output and enhances peripheral glucose uptake. Metformin is used as a monotherapy in combination with other oral hypoglycemic agents.
Riyazuddin S. H. Ansari   +5 more
doaj   +1 more source

Safety of anagliptin/metformin combination tablets evaluated by non‐inferiority between pre‐ and post‐serum lactic acid levels in Japanese patients with type 2 diabetes and moderate renal impairment (AMELIO STUDY)

open access: yesJournal of Diabetes Investigation, EarlyView.
To investigate the safety of anagliptin/metformin combination tablets in Japanese patients of type 2 diabetes with moderate renal impairment. This study demonstrates that the fixed‐dose combination of anagliptin and metformin can be used safely in patients with type 2 diabetes complicated by moderate renal dysfunction.
Hiroshi Kajio   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy