Results 151 to 160 of about 64,694 (238)

Multifacet Roles of Cellular Senescence in Cancer: Mechanisms and Therapeutic Implications

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Cellular senescence shapes tumor progression through both antitumor and protumor mechanisms. Senescence triggered by telomere shortening restricts malignant transformation and limits tumor cell proliferation, while the senescence‐associated secretory phenotype (SASP) secretion enhances antitumor immunity by activating cytotoxic T cells.
Huajie Mao, Wanning Liu, Yuanyuan Su, Yuxuan Ma, Xiaodi Zhao, Yuanyuan Lu   +5 more
wiley   +1 more source

European Society for the Study of Coeliac Disease (ESsCD) 2025 Updated Guidelines on the Diagnosis and Management of Coeliac Disease in Adults. Part 2: Management, Follow‐Up, and Complex Disease Courses

United European Gastroenterology Journal, Volume 14, Issue 2, March 2026.
ABSTRACT Introduction Since the publication of the first European Society for the Study of Coeliac Disease (ESsCD) guidelines in 2019, substantial advances have been made in understanding the management and complex disease courses of coeliac disease (CeD) in adults.
Abdulbaqi Al‐Toma, Federica Branchi, Fabiana Zingone, Annalisa Schiepatti, Georgia Malamut, Cristina Canova, Isabella Rosato, Honoria Ocagli, Nick Trott, Luca Elli, Alina Popp, Carmen Gianfrani, Renata Auricchio, Andra Neefjes‐Borst, David S. Sanders, Christophe Cellier, Chris J. Mulder, Gerd Bouma, Knut E. A. Lundin, Ludvig M. Sollid, Michael Schumann   +20 more
wiley   +1 more source

Short‐Term Impact of Betaine Supplementation on Ruminal Microbial Relative Abundance, Nutrient Digestibility, Serum Metabolites, and Milk Composition in Heat‐Stressed Dairy Cows

Veterinary Medicine and Science, Volume 12, Issue 2, March 2026.
Short‐term betaine supplementation (80 g/day for 4 weeks) improved thermoregulation, ruminal fermentation, and nutrient utilisation in heat‐stressed dairy cows. These effects enhanced feed intake, milk yield, and metabolic stability by modulating rumen microbiota and reducing inflammatory and oxidative stress responses.
Mohamed Abdelmegeid, Walaa Elhendawy, Helmy Kamal Elnafarawy, Mohamed Zeineldin, Rabiha Seboussi, Mustafa Shukry, Mohamed Donia, Aboma Zewude, Gobena Ameni, Hazim O. Khalifa, Naglaa Gomaa, Ahmed A. Elolimy, Midhat Nassif   +12 more
wiley   +1 more source

The effect of short-term antiorthostatic hypokinesia on central and intracardiac hemodynamics and metabolism of a healthy person [PDF]

The right parts of the heart and the radial artery were catheterized in healthy male volunteers before and 5 days after strict bedrest in antiorthostatic position of the body (-4.5 deg).
Abrosimov, S. V., Chesturkhin, V. V., Katkov, V. Y., Sukhotskiy, S. S., Utkin, V. N., Zybin, O. K.   +5 more
core   +1 more source

Incidents of sudden death during restraint of agitated individuals in Sweden between 1992 and 2024

Journal of Forensic Sciences, Volume 71, Issue 2, Page 821-836, March 2026.
Abstract Restraint‐related sudden deaths in agitated individuals raise complex questions at the intersection of medicine and law. Hyperactive delirium with extreme agitation as well as positional asphyxia due to restraint have been proposed to account for these deaths. However, the exact physiological mechanisms responsible and to what extent restraint
Alexander Tyr, Erik Lindeman, Fredrik Tamsen, Ingemar Thiblin, Brita Zilg   +4 more
wiley   +1 more source

Acute liver failure and severe lactic acidosis as initial manifestations of primary intestinal diffuse large B-cell lymphoma: Case report. [PDF]

Leuk Res Rep
Mori H, Miura S, Soeda M, Imaizumi Y.
europepmc   +1 more source

Myophosphorylase Knock Out Prevents the Exaggerated Exercise Pressor Reflex in Rats With Simulated Peripheral Artery Disease

Acta Physiologica, Volume 242, Issue 3, March 2026.
ABSTRACT Aim Controversy exists on which metabolites determine the exaggerated exercise pressor reflex (EPR) in peripheral artery disease (PAD). In decerebrated rats, we investigated the role played by lactate and hydrogen ions in a model of PAD, which was simulated by ligating the femoral artery for 72 h before the start of the experiment.
Guillaume P. Ducrocq, Laura Anselmi, Victor Ruiz‐Velasco, Marc P. Kaufman   +3 more
wiley   +1 more source

Metformin-associated lactic acidosis in an elderly diabetic patient without classical risk factors: a case report. [PDF]

Ther Adv Drug Saf
Zheng Y, Sun J, Zhang P, Zhu Q.
europepmc   +1 more source

Epidemiology of progressive intellectual and neurological deterioration in UK children

Developmental Medicine &Child Neurology, Volume 68, Issue 3, Page 418-428, March 2026.
This study of PIND in UK children was carried out via the British Paediatric Surveillance Unit from 1997 to 2024. It identified six cases of vCJD. 2367 children had other diagnoses explain their deterioration. There were 259 other diseases in the diagnosed group.
Christopher M. Verity, Polly J. Maunder, Anne Marie Winstone, Suvankar Pal   +3 more
wiley   +1 more source

Severe Multifactorial Lactic Acidosis With Pulmonary Edema and Myocardial Injury in an Elderly Patient on Metformin Managed Conservatively: A Case Report. [PDF]

Cureus
Zin Aung K, Cho EE, Htun SS, Zin NA, Soe TT, Thant Thant H, Myint C, Saw NEL.   +7 more
europepmc   +1 more source