Results 11 to 20 of about 64,694 (238)

Metformin-Associated Lactic Acidosis [PDF]

open access: yesEndocrinology and Metabolism, 2015
Introduction Metformin is a first line oral medication for diabetes mellitus shown to decrease cardiovascular morbidity and mortality. Though the prevalence of metformin-associated lactic acidosis (MALA) is low, mortality is high, ranging from 25-50 ...
Sunghwan Suh
doaj   +4 more sources

Severe Metformin-Associated Lactic Acidosis-A Case Report. [PDF]

open access: yesClin Case Rep
ABSTRACT Metformin, a widely prescribed and generally safe drug for diabetes mellitus, can rarely lead to metformin‐associated lactic acidosis—a severe, potentially fatal complication. Early recognition, emergency hemodialysis, and supportive management are crucial for favorable outcomes, highlighting the importance of prompt diagnosis and intervention
Artinyan E   +7 more
europepmc   +2 more sources

Metformin, Sulfonylureas, or Other Antidiabetes Drugs and the Risk of Lactic Acidosis or Hypoglycemia [PDF]

open access: yes, 2011
OBJECTIVE: Lactic acidosis has been associated with use of metformin. Hypoglycemia is a major concern using sulfonylureas. The aim of this study was to compare the risk of lactic acidosis and hypoglycemia among patients with type 2 diabetes using oral ...
Bodmer, Michael   +4 more
core   +2 more sources

Severe drug-induced liver injury associated with prolonged use of Linezolid [PDF]

open access: yes, 2010
This study aims to describe a patient developing concomitant severe liver failure and lactic acidosis after long-term treatment with linezolid. A 55-year-old Caucasian woman developed concomitant severe liver failure and lactic acidosis after a treatment
Benoit, Dominique   +7 more
core   +1 more source

Type B Lactic Acidosis in a Patient with Mantle Cell Lymphoma

open access: yesCase Reports in Critical Care, 2023
Type B lactic acidosis is an uncommon medical emergency in which acid production overwhelms hepatic clearance. This specific etiology of lactic acidosis occurs without organ hypoperfusion and has been most commonly described in patients with hematologic ...
Ikemsinachi C. Nzenwa   +12 more
doaj   +1 more source

Point-of-care measurement of blood lactate in children admitted with febrile illness to an African District Hospital. [PDF]

open access: yes, 2011
BACKGROUND: Lactic acidosis is a consistent predictor of mortality owing to severe infectious disease, but its detection in low-income settings is limited to the clinical sign of "deep breathing" because of the lack of accessible technology for its ...
Acierno   +22 more
core   +1 more source

Oral health in two heterozygote female twins with congenital lactic acidosis [PDF]

open access: yes, 2017
Introduction: Congenital lactic acidosis (CLA) is a rare disease caused by mutations in Mithocondrial DNA (mtDNA), which affects the ability of cells to use energy that causes accumulation of lactic acid in the body.
GUERRA, Fabrizio   +4 more
core   +1 more source

A patient with metformin-associated lactic acidosis successfully treated with continuous renal replacement therapy: a case report

open access: yesJournal of Medical Case Reports, 2019
Background Metformin has been widely used as a first-line agent to treat type 2 diabetes mellitus. Lactic acidosis is a rare but serious adverse effect in patients treated with metformin.
Hiroki Kinoshita   +4 more
doaj   +1 more source

Severe Lactic Acidosis in a Patient with B-Cell Lymphoma: A Case Report and Review of the Literature

open access: yesCase Reports in Medicine, 2009
Lactic acidosis is commonly observed in clinical situations such as shock and sepsis, as a result of tissue hypoperfusion and hypoxia. Lymphoma and leukemia are among other clinical situations where lactic acidosis has been reported. We present a case of
Farn Huei Chan   +2 more
doaj   +1 more source

Type B lactic acidosis associated with diffuse large B-cell lymphoma and the Warburg effect

open access: yesJournal of International Medical Research, 2022
Type B lactic acidosis is a rare complication of non-tissue perfusion abnormalities caused by solid tumors or hematologic malignancies. Herein, we present the case of a 42-year-old man with type B lactic acidosis and hypoglycemia who was found to have a ...
Chunhua Wang, Zanmei Lv, Yanwei Zhang
doaj   +1 more source

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