Variants in ACPP are associated with cerebrospinal fluid Prostatic Acid Phosphatase levels [PDF]
Prostatic Acid Phosphatase (PAP) is an enzyme that is produced primarily in the prostate and functions as a cell growth regulator and potential tumor suppressor. Understanding the genetic regulation of this enzyme is important because PAP plays an important role in prostate cancer and is expressed in other tissues such as the brain.We tested ...
Staley, Lyndsay A. +6 more
openaire +2 more sources
Tumor microenvironment-responsive metal nanotherapeutics for breast cancer chemo-/immunotherapy
Many metal complexes not only had excellent cytotoxic antitumor effects but also could function as a positive immunomodulatory to improve antitumor effects by modifying the local tumor microenvironment.
Jinggong Liu +10 more
doaj +1 more source
Membrane type-1 matrix metalloproteinase (MT1-MMP or MMP-14) plays an important role in adverse cardiac remodelling. Here, we aimed to develop radiolabeled activatable cell penetrating peptides (ACPP) sensitive to MT1-MMP for the detection of elevated ...
Sander M. J. van Duijnhoven +3 more
doaj +1 more source
Cell-penetrating peptides and their analogues as novel nanocarriers for drug delivery [PDF]
Introduction: The impermeability of biological membranes is a major obstacle in drug delivery; however, some peptides have transition capabilities of biomembranes.
Samira Jafari +2 more
doaj +1 more source
Ancient Chinese poetry and prose (ACPP) are the essence of traditional Chinese culture and also literary gems of the world. Despite the long tradition of previous Chinese Presidents using ACPP in their political addresses, the translation work on the ...
Qiannan Liu, Xiaolong Li
doaj +1 more source
Antisense PNA accumulates in Escherichia coli and mediates a long post-antibiotic effect [PDF]
Antisense agents that target growth-essential genes display surprisingly potent bactericidal properties. In particular, peptide nucleic acid (PNA) and phosphorodiamidate morpholino oligomers linked to cationic carrier peptides are effective in time kill ...
Behmanesh, Mehrdad +9 more
core +2 more sources
Finding Biomass Degrading Enzymes Through an Activity-Correlated Quantitative Proteomics Platform (ACPP) [PDF]
The microbial secretome, known as a pool of biomass (i.e., plant-based materials) degrading enzymes, can be utilized to discover industrial enzyme candidates for biofuel production. Proteomics approaches have been applied to discover novel enzyme candidates through comparing protein expression profiles with enzyme activity of the whole secretome under ...
Hongyan, Ma +4 more
openaire +2 more sources
The Prostatic Acid Phosphatase (ACPP) Gene Is Localized to Human Chromosome 3q21-q23 [PDF]
Human prostatic acid phosphatase (ACPP) has been used as a diagnostic marker for prostate cancer. It is synthesized under androgen regulation and secreted by the epithelial cells of the prostate gland. We have confirmed the previous assignment of the ACPP gene to chromosome 3 by probing a panel of 25 human-Chinese hamster somatic cell hybrids, and we ...
S S, Li, F S, Sharief
openaire +2 more sources
Is the strong-interaction proton-proton scattering length renormalization scale dependent in effective field theory? [PDF]
It is shown that the strong-interaction ${}^1S_0$ proton-proton scattering length in very low-energy effective field theory does not depend on the renormalization scale, if the electromagnetic interaction is "switched off" consistently.Comment: 9 pages ...
Gegelia, J.
core +1 more source
Proton-Proton Scattering Lengths from Effective Field Theory [PDF]
Using a recently developed effective field theory for the interactions of nucleons at non-relativistic energies, we calculate the Coulomb corrections to proton-proton scattering.
Bethe +7 more
core +4 more sources

