Results 31 to 40 of about 45,976 (189)

In Situ Synthesis of Covalent Organic Frameworks Inside Cells for Triggering Ferroptosis and Immunotherapy

Advanced Materials, EarlyView.
We have developed an intracellular crystalline polymerization strategy involving acid‐catalyzed imine condensation to synthesize COFs in lysosomes. The generation of COFs in lysosomes damages their integrity, activates iron species, and induces immunogenic ferroptosis, thereby enhancing antitumor immunotherapy.
Qun Guan, Le‐Le Zhou, Zhiqing Yang, Yan‐An Li, Leyong Wang, Ruibing Wang   +5 more
wiley   +1 more source

Design, Synthesis, Antimicrobial, and Anticancer Activities of Acridine Thiosemicarbazides Derivatives

Molecules, 2019
Background: Acridine and thiourea derivatives are important compounds in medicinal chemistry due to their diverse biological properties including anticancer and antimicrobial effects.
Rui Chen, Lini Huo, Yogini Jaiswal, Jiayong Huang, Zhenguo Zhong, Jing Zhong, Leonard Williams, Xing Xia, Yan Liang, Zhenshuo Yan   +9 more
doaj   +1 more source

Role of the Recombination Zone in Organic Light‐Emitting Devices

Advanced Materials, EarlyView.
This review summarizes the critical role of the recombination zone in organic light‐emitting diodes (OLEDs). We highlight that broadening the recombination zone in OLEDs based on emissive layers with balanced charge transport and high photoluminescence quantum yields provides a promising route toward achieving both long operational lifetime and high ...
Yungui Li, Karl Leo
wiley   +1 more source

Synthesis of Acridines through Alkyne Addition to Diarylamines

Molecules, 2018
A new synthesis of substituted acridines is achieved by palladium-catalyzed addition of terminal acetylenes between the aryl rings of bis(2-bromophenyl)amine.
Kristen E. Berger, Grant M. McCormick, Joseph A. Jaye, Christina M. Rozeske, Eric H. Fort   +4 more
doaj   +1 more source

Self‐Assembled Monolayers in p–i–n Perovskite Solar Cells: Molecular Design, Interfacial Engineering, and Machine Learning–Accelerated Material Discovery

Advanced Materials, EarlyView.
This review highlights the role of self‐assembled monolayers (SAMs) in perovskite solar cells, covering molecular engineering, multifunctional interface regulation, machine learning (ML) accelerated discovery, advanced device architectures, and pathways toward scalable fabrication and commercialization for high‐efficiency and stable single‐junction and
Asmat Ullah, Ying Luo, Stefaan De Wolf
wiley   +1 more source

Acridine-Triphenylamine Based Hole-Transporting and Hole-Injecting Material for Highly Efficient Phosphorescent-Based Organic Light Emitting Diodes

Applied Sciences, 2018
In this study, triphenylamine-based hole-transporting material 4-(9,9-diphenylacridin-10(9H)-yl)-N-(4-(9,9-diphenylacridin-10(9H)-yl) phenyl)-N-phenylaniline (TPA-1A) was designed and synthesized by using single-step Buchwald–Hartwig coupling ...
Ramanaskanda Braveenth, Il-Ji Bae, Yan Wang, Soo Hyeon Kim, Miyoung Kim, Kyu Yun Chai   +5 more
doaj   +1 more source

An Acridine-Based Fluorescent Sensor for Monitoring ClO⁻ in Water Samples and Zebrafish

Sensors, 2020
A novel acridine-based fluorescent chemosensor, BK ((E)-2-((acridine-9-ylimino)methyl)-N-benzhydrylhydrazine-1-carbothioamide), for monitoring ClO− was prepared.
Su Chan Lee, Soyoung Park, Haeri So, Gyudong Lee, Ki-Tae Kim, Cheal Kim   +5 more
doaj   +1 more source

3D Printed Multimaterial Microfluidic Transistors

Advanced Materials Technologies, EarlyView.
We introduce a biocompatible, high resolution photopolymer resin that closely mimics the Young's Modulus (elasticity) and reversible stretchability (no hysteresis) of poly(dimethylsiloxane) (PDMS), enabling the fabrication of microfluidic transistors (i.e., microvalves capable of proportional amplification) by multimaterial stereolithography (mSLA ...
Alireza Ahmadianyazdi, Wei Huang, Kaustav A. Gopinathan, Ivan Stepanov, Lisa Horowitz, Ting‐Yuan Tu, Mehmet Toner, Albert Folch   +7 more
wiley   +1 more source

Steric and Electronic Effects in N-Heterocyclic Carbene Gold(III) Complexes: An Experimental and Computational Study

Molecules, 2022
A series of neutral acridine-based gold(III)-NHC complexes containing the pentafluorophenyl (–C6F5) group were synthesized. All of the complexes were fully characterized by analytical techniques.
Miguel A. Rosero-Mafla, Jhon Zapata-Rivera, M. Concepción Gimeno, Renso Visbal   +3 more
doaj   +1 more source

Microfluidic Hydroporation Platform for Effective Allogeneic CAR‐T Cell Production and Subsequent Functional Cytotoxicity Analysis

Advanced Materials Technologies, EarlyView.
The hydroporator platform employs controlled hydrodynamic deformation for efficient mRNA and CRISPR/Cas9 delivery into primary human T cells, enabling allogeneic CAR‐T cell manufacturing. It preserves cell functionality and drives potent gene editing, CAR expression, and tumor cytotoxicity, while feature‐based analysis links these functional outcomes ...
Soohyun Jeon, Sein Kim, Hyun‐Young Kim, Duck Cho, Sungsu Park, Seohyun Kim, Aram J. Chung   +6 more
wiley   +1 more source