Results 61 to 70 of about 40,079 (224)
MoleculesThis study focuses on the synthesis and structural characterization of new compounds that integrate thiazolidine-2,4-dione, acridine moiety, and an acetamide linker, aiming to leverage the synergistic effects of these pharmacophores for enhanced ...
Monika Garberová +8 more
doaj +1 more source
Synthesis of Acridines through Alkyne Addition to Diarylamines
Molecules, 2018 A new synthesis of substituted acridines is achieved by palladium-catalyzed addition of terminal acetylenes between the aryl rings of bis(2-bromophenyl)amine.
Kristen E. Berger +4 more
doaj +1 more source
Chemistry – A European Journal, EarlyView.The synthesis of dithieno[3,2‐b:2′,3′‐e]pyridines (DTPs) is herein reported, and their optical properties are studied both experimentally and computationally. Protonation or methylation of the nitrogen atom induced bathochromic shifts in their absorption and emission spectra.
Dominic Taylor +7 more
wiley +1 more source
Applied Sciences, 2018 In this study, triphenylamine-based hole-transporting material 4-(9,9-diphenylacridin-10(9H)-yl)-N-(4-(9,9-diphenylacridin-10(9H)-yl) phenyl)-N-phenylaniline (TPA-1A) was designed and synthesized by using single-step Buchwald–Hartwig coupling ...
Ramanaskanda Braveenth +5 more
doaj +1 more source
Lysosome‐Targeted Squaramide Anion Transporters
Chemistry – A European Journal, EarlyView.Lysosome‐targeted squaramide anion transporters elicit different biological effects depending on the targeting group employed. ABSTRACT Targeting anion transporters to specific organelles has previously been shown to be an effective strategy to enhance their cytotoxicities against cancerous cell lines.
Elba Feo +5 more
wiley +1 more source
A review of published data on acridine derivatives with different biological activities [PDF]
Kragujevac Journal of Science, 2018 Acridine ring can be found in molecules used in many different spheres, including industry and medicine. Nowadays, even acridines with antibacterial activity are of research interest due to increasing bacterial resistance.
Rupar Jelena S. +4 more
doaj
Characterization of the Interaction of Known G‐quadruplex Ligands With a Minimal i‐Motif Structure
Chemistry – A European Journal, EarlyView.The destabilization of a minimal i‐Motif (iM) structure by TMPyP4 is driven by ligand recognition of one terminal iM structural domain. ABSTRACT Peculiar genomic regions are prone to evolve transiently from double‐helix DNA to noncanonical secondary structures in response to physiological stress.
Davide Auricchio +3 more
wiley +1 more source
SYNTHESIS OF SOME SUBSTITUTED ACRIDINE DERIVATIVES OF ANTICIPATED ANTICANCER ACTIVITY
Zagazig Journal of Pharmaceutical Sciences, 2009 In the present investigation four series of new acridine derivatives of anticipated antitumor activity have been Synthesized. The first series belongs to 9-phenylimino-acridine-10-acetate derivatives.
Samir Aly +3 more
doaj +1 more source
Chemistry – A European Journal, EarlyView.A comprehensive experimental and theoretical study is presented of a family of TADF dyes. Comparing the behavior of structurally related dyes, we uncover the subtle and somewhat unexpected role of conformational degrees of freedom associated with peripheral groups that affect the delicate interplay of excited states that governs spin–orbit coupling ...
Andrea Landi +7 more
wiley +1 more source