Results 131 to 140 of about 3,278 (246)

Synthesis of Heterocycles via Pd-Ligand Controlled Cyclization of 2-Chloro-N-(2-vinyl)aniline: Preparation of Carbazoles, Indoles, Dibenzazepines, and Acridines

, 2016
The Pd-catalyzed condensation of 2-bromostyrene and 2-chloroaniline derivatives yields stable diphenylamine intermediates, which are selectively converted to five-, six-, or seven-membered heteroaromatics (indoles, carbazoles, acridines, and ...
Stephen L. Buchwald (1307121), Dmitry Tsvelikhovsky (1489750)   +1 more
core   +1 more source

Glial Dysfunction and Memory Impairments in a Model of Pediatric Obstructive Sleep Apnea

Glia, Volume 74, Issue 11, November 2026.
Generation and analysis of an snRNA‐seq atlas of the hippocampus in POSA. Validation of reduced protein expression of six genes across four cell types. Cellular‐level investigation of aberrant glial function in POSA using transgenic reporter mice. ABSTRACT Pediatric obstructive sleep apnea (POSA) is a common childhood disease that often causes aberrant
Michael R. Williamson, Jorge Botas, Mahyar J. Hedayatpour, Thea Zlatkov, Akdes Serin Harmanci, Christopher J. Yates, Kenneth Nobleza, Roshan Ailani, Adam C. Adler, Farrah Kheradmand, Hyun Kyoung Lee, Benjamin Deneen, Hyun‐Hwan Jeong, Arvind Chandrakantan   +13 more
wiley   +1 more source

Insertion of benzene rings into the amide bond: one-step synthesis of acridines and acridones from aryl amides

, 2009
"Chemical Equation Presented" Insertion of benzene rings into the amide bond using the reactive intermediate benzyne is described. Aromatic amides undergo smooth insertion when treated with O-triflatophenyl silane benzyne precursors, producing versatile ...
Greaney, Michael F., Pintori, Didier G., Didier G. Pintori, Michael F. Greaney   +3 more
core   +1 more source

Health Biomarkers of Pesticide Exposure in Rural Populations of Santa Fe, Argentina: Oxidative Stress and Genotoxicity

Journal of Applied Toxicology, Volume 46, Issue 11, Page 3804-3813, November 2026.
ABSTRACT The present study aimed to quantify pesticide residues in environmental matrices and plasma and to evaluate their potential effects on oxidative stress and DNA damage in rural populations of Santa Fe province. Soil and rainwater samples were collected, and biological samples and semistructured surveys were obtained from volunteers in three ...
María Priscila Dechiara, Carlina Leila Colussi, Lucía Magdalena Odetti, Damián Marino, María Fernanda Simoniello   +4 more
wiley   +1 more source

Ultrasound-assisted nanoparticles catalyzed multicomponent reactions: recent progress in bioactive heterocycle synthesis

Green Chemistry Letters and Reviews
In light of growing concerns toward greener and more eco-friendly methods of organic synthesis, ultrasound-mediated nanocatalysis has emerged as a potent and robust technique in current organic chemistry, particularly for the preparation of heterocycles ...
K. Venkatesan, Jayanthi Barasarathi, Maher Fathalla, Xiao-Hui Chu, Ling Shing Wong, Hai-Anh Ha, Lai-Hock Tey   +6 more
doaj   +1 more source

Synergistic Effects of Thyroxine and Nano‐Melatonin on Post‐Thaw Sperm Quality, Antioxidant Defence and Fertility of Cryopreserved Simmental Bull Semen

Veterinary Medicine and Science, Volume 12, Issue 6, November 2026.
Effects of thyroxine (T) and nano‐melatonin (NM) supplementation on cryopreserved Simmental bull semen were evaluated. The combination of thyroxine (0.5 µg/dL) and nano‐melatonin (30 µg/dL) significantly improved post‐thaw sperm motility, membrane integrity, antioxidant status, and fertility while reducing oxidative stress and apoptosis. These findings
Marwa Abonagy, Ahmed Arisha, Maha Salama, Mohey Ashour, Mustafa Shukry, Sameh Shedeed, Ahmed Shehabeldin, Nagi El‐Shafai, Zein Ibrahim, Shawky Mahmoud, Michel Saad, Ahmed Alameen, Rasha Yassin Elkhidr, Osama Hassan Ali, Arafat Khalphallah, Enas Elmeligy, Khaled Abdulaziz Khesruf, Enas Ahmed Abdelhafez, Alaa Algabary   +18 more
wiley   +1 more source

Structure and stability of human telomeric G-quadruplex with preclinical 9-amino acridines

G-quadruplexes are higher-order DNA structures formed from guanine-rich sequences, and have been identified as attractive anticancer drug targets.
Gargallo Gómez, Raimundo, Benoit, Adam, Ferguson, David M., Artali, Roberto, Ferreira Aguilera, Rubén, Eritja i Casadellà, Ramon, Mazzini, Stefania, Sham, Yuk Y.   +7 more
core  

Hypercapnia Induces Mitochondrial Adaptations and Alters Glutamine Metabolism to Drive a Distinct Metabolic Phenotype in Monocytes

Immunology &Cell Biology, Volume 104, Issue 10, Page 943-963, November‐December 2026.
Elevated CO2 (hypercapnia) is a feature of serious lung diseases, for example COPD and contributes to poor patient prognosis through modulation of immune cell function. Here we employ state‐of‐the art metabolomic and isotope tracing approaches to reveal CO2‐dependent mitochondrial alterations linked to suppressed ATP, proline and glutamate levels in ...
Ben Reddan, David E. Phelan, Xiaofei Yin, Lorraine Brennan, Martina Wallace, Eoin P. Cummins   +5 more
wiley   +1 more source

sj-docx-1-chl-10.1177_17475198241228252 – Supplemental material for Thermo-promoted annulation of arylboronic acids with anthranils under catalyst-free conditions: Access to acridines

Supplemental material, sj-docx-1-chl-10.1177_17475198241228252 for Thermo-promoted annulation of arylboronic acids with anthranils under catalyst-free conditions: Access to acridines by Jing Jiang, Peng Xie, Yue Gao, Chenqi Wu and Jingcheng Song in ...
Jingcheng Song (17903208), Jing Jiang (130103), Chenqi Wu (17903205), Yue Gao (263086), Peng Xie (161786)   +4 more
core   +1 more source

Synthesis of Heterocycles via Pd-Ligand Controlled Cyclization of 2-Chloro-N-(2-vinyl)aniline: Preparation of Carbazoles, Indoles, Dibenzazepines and Acridines

, 2010
The Pd-catalyzed condensation of 2-bromostyrene and 2-chloroaniline derivatives yields stable diphenylamine intermediates, which are selectively converted to five-, six-, or seven-membered heteroaromatics (indoles, carbazoles, acridines, and ...
Stephen L. Buchwald, Tsvelikhovsky, Dmitry, Buchwald, Stephen Leffler, Dmitry Tsvelikhovsky   +3 more
core   +1 more source