Results 111 to 120 of about 28,434 (232)

Ex vivo fluorescence confocal microscopy for assessment of ureteroscopic biopsy adequacy in upper tract urothelial carcinoma

open access: yesBJU International, EarlyView.
Objectives To evaluate the feasibility of ex vivo fluorescence confocal microscopy (FCM) for real‐time assessment of ureteroscopic biopsy specimen adequacy in patients with suspected upper tract urothelial carcinoma (UTUC). Patients and Methods In this prospective, single‐centre feasibility study, four ureteroscopic biopsy specimens obtained from two ...
Karim Daher   +14 more
wiley   +1 more source

Degrees of Sulfonation: Mapping the Reactivity Landscape of Acridine and Acridone

open access: yesOrganics
Although sulfonated acridines and acridones are valuable scaffolds in diagnostics and materials science, to our best knowledge, there is no comprehensive study that addresses how the degree of sulfonation depends on reaction parameters. To fill this gap,
Péter Kisfaludi   +3 more
doaj   +1 more source

Interaction of Bioactive Pyrazolo[4,3-a]acridines with Human Serum Albumin [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering, 2017
Several heterocyclic bioactive fluorescent 3-alkyl-3H-pyrazolo[4,3-a]acridin-11-carbonitriles were conveniently synthesized from the reaction of 1-alkyl-1H-indazoles with different aryl acetonitrile in basic methanol solution in good yields.
Fatemeh Khosravi   +2 more
doaj  

Synthesis of azepane-acridine heterocyclic adducts assisted by the catalytic influence of γ-Fe2O3@TiO2-Vitamin B1 and evaluation of their medicinal potential through in vitro antimicrobial, QSAR, and molecular docking studies

open access: yesResults in Chemistry
Present work elicits synthesis of novel azepane-acridines, assisted by titania-encapsulated γFe2O3 nanoparticles supported on Vitamin B1 (γFe2O3@TiO2-Vitamin B1) as a new magnetically recyclable heterogeneous nano-catalytic system.
Shweta Potdar   +3 more
doaj   +1 more source

Новые люминесцентные зонды для нуклеиновых кислот на основе эксимеров цианинового красителя [PDF]

open access: yes, 2009
При помощи методов оптической спектроскопии были исследованы особенности взаимодействия производных оксакарбоцианинового красителя (С2, С6 и С9), отличающихся длиной углеводородного радикала, с нуклеиновыми кислотами (ДНК и РНК).
Боровой, И.А.   +5 more
core  

Cyclin‐dependent kinase 13 is indispensable for normal mouse heart development

open access: yesJournal of Anatomy, Volume 246, Issue 4, Page 616-630, April 2025.
Congenital heart disease (CHD) is the most common defect in live births. The role of cyclin‐dependent kinase (CDK13) in cardiogenesis and CHD was studied using a transgenic mouse model (Cdk13tm1b) carrying deletion of exons 3 and 4, causing loss of function.
Qazi Waheed‐Ullah   +8 more
wiley   +1 more source

Photoprotective potential of gadusol against ultraviolet B radiation in melanocytes

open access: yesPhotochemistry and Photobiology, EarlyView.
Gadusol protects melanocytes from ultraviolet B (UVB)‐induced damage without cytotoxicity. Abstract The increasing incidence of skin cancer, including melanoma, combined with the need for ultraviolet (UV) filters that are safe for human health and marine ecosystems, is driving the search for new photoprotective agents.
Andressa Mai Matsumoto   +8 more
wiley   +1 more source

Zebrafish as a practical and convenient model for the study of photodynamic and photothermal therapy of solid tumors: A scoping review

open access: yesPhotochemistry and Photobiology, EarlyView.
Zebrafish provide a high‐throughput, optically transparent platform for cancer and drug screening. Their ~80% genetic homology, xenograft compatibility, and transgenic strains enable targeted photosensitizer screening, real‐time ROS and tumor imaging, and mechanistic assays, while fish embryo acute toxicity (FET) and in vitro tests streamline toxicity ...
Ethan Wilson   +5 more
wiley   +1 more source

Study on Changes of Sperm Head Morphometry and Dna Integrity of Freeze-dried Bovine Spermatozoa [PDF]

open access: yes, 2015
Changes of sperm heads morphometric and DNA integrity of freeze-dried bovine spermatozoa were investigated. Freeze-dried spermatozoa had stored in the refrigerator at 4°C for 2 years.
Afiati, F. (F)   +2 more
core  

Phenothiazinium photoantimicrobials with basic side chains [PDF]

open access: yes
Derivatives of the standard cationic photosensitiser, methylene blue, were synthesised, having extra amino (basic) functionality in the auxochromic side-chain. The resulting analogues were profiled for photodynamic activity in vitro, and screened against
Ah   +24 more
core   +1 more source

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