Results 111 to 120 of about 3,278 (246)
The FEBS Journal, EarlyView.Human AIMP2 mutations lead to severe neurodevelopmental defects and brain atrophy. Using patient‐derived fibroblasts from two individuals, we show decreased AIMP2 protein levels and overall protein synthesis. In a zebrafish loss‐of‐function model, the lack of AIMP2 leads to an increase in cell death and results in smaller brains.
Patrick Mullen +10 more
wiley +1 more source
Cyclin‐dependent kinase 13 is indispensable for normal mouse heart development
Journal of Anatomy, Volume 246, Issue 4, Page 616-630, April 2025.Congenital heart disease (CHD) is the most common defect in live births. The role of cyclin‐dependent kinase (CDK13) in cardiogenesis and CHD was studied using a transgenic mouse model (Cdk13tm1b) carrying deletion of exons 3 and 4, causing loss of function.
Qazi Waheed‐Ullah +8 more
wiley +1 more source
Interaction of Bioactive Pyrazolo[4,3-a]acridines with Human Serum Albumin [PDF]
Iranian Journal of Chemistry & Chemical Engineering, 2017 Several heterocyclic bioactive fluorescent 3-alkyl-3H-pyrazolo[4,3-a]acridin-11-carbonitriles were conveniently synthesized from the reaction of 1-alkyl-1H-indazoles with different aryl acetonitrile in basic methanol solution in good yields.
Fatemeh Khosravi +2 more
doaj
ACRIDINE DERIVATIVES. PART V. AUROTHlO- AND ARGENTOTHIO-ACRIDINES.
, 1940 Gold and silver compounds of 5-thiolacridine derivatives have been described.
openaire +2 more sources
Photoprotective potential of gadusol against ultraviolet B radiation in melanocytes
Photochemistry and Photobiology, EarlyView.Gadusol protects melanocytes from ultraviolet B (UVB)‐induced damage without cytotoxicity. Abstract The increasing incidence of skin cancer, including melanoma, combined with the need for ultraviolet (UV) filters that are safe for human health and marine ecosystems, is driving the search for new photoprotective agents.
Andressa Mai Matsumoto +8 more
wiley +1 more source
ACRIDINE DERIVATIVES. PART VI.
, 1941 Certain sulphanilamido-acridines and acridyl aminobenzenesulphonamide derivatives have been ...
S. J . DAS-GUPTA
core +1 more source
, 1945 Certain 5-(diethylamino-alkyl)-aminoacridines have been prepared. Their basicity as well as the antiseptic properties have been recorded.
P. DAS-GUPTA, P. GUPTA
openaire +2 more sources
The role of acquired host immunity in periodontal diseases
Periodontology 2000, EarlyView.Abstract The aim of this narrative review is to relate the contribution of European researchers to the complex topic of the host immune system in periodontal disease, focusing on acquired immunity. Other chapters in this volume will address the genetics and autoantibody responses and other forms of immunity to periodontal disease.
Denis F. Kinane +2 more
wiley +1 more source
, 2018 Fluorinated unsymmetrical acridines are efficiently prepared by means of a tandem micellar Buchwald–Hartwig amination followed by an acid-promoted cyclization.
Mauro Sassi +5 more
core +1 more source