Results 91 to 100 of about 3,278 (246)
An expedient synthesis of isoxazolo - and pyrazolo-[3,4-a]acridines with molecular docking studies [PDF]
, 2018 345-354An efficient synthesis of isoxazolo[3,4-a]acridines from 7-chloro-9-phenyl-2-(aryl-2'-ylmethylene)-3,4-dihydroacridin-1(2H)-one obtained from 7-chloro-9-phenyl-3,4-dihydroacridin-1(2H)-one with arylaldehyde in presence of alcoholic sodium ...
Praveenkumar, K +3 more
core
Responsive Materials, EarlyView.The lysosome‐localized copper‐doped carbon dots (Cu‐MLCDs) leverage the high expression of glutathione (GSH)/H2O2 in the tumor microenvironment to achieve fluorescence reactivation enhancement. Through its multi‐nanozyme activities (glutathione peroxidase, peroxidase, and catalase), this nanoplatform relieves hypoxia, depletes GSH, and synergistically ...
Weixia Qin +8 more
wiley +1 more source
, 2016 Highly selective four-component domino multicyclizations for the synthesis of new fused acridines and azaheterocyclic skeletons have been established by mixing common reactants in isobutyric acid under microwave irradiation.
Hai-Wei Xu (1643125) +5 more
core +1 more source
, 2016 A new aminobenzannulation methodology has been developed and applied successfully to the synthesis of 1-amino-acridines. The key and last step goes through an enamine intermediate that was detected in some cases.
Tahar Belhadj (2684923) +1 more
core +2 more sources
A photoimmune synergizing RNA interference technology for highly effective antitumor treatment
Smart Molecules, EarlyView.We developed a red‐light‐activated small‐molecule photosensitizer FNBS, which enables simultaneous photodynamic immunotherapy and RNA interference. FNBS can induce pyroptosis, immunogenic cell death and RNA degradation, avoiding the carrier‐dependent delivery drawbacks of conventional RNAi therapy, converting cold tumors into hot tumors and ...
Xiang Xia +6 more
wiley +1 more source
, 2018 The transient directing group promoted C(sp2)–H functionalization of benzaldehydes with anthranils by a cationic rhodium(III) catalyst is described. Notably, anthranils have been used as both transient directing groups and amination sources to afford 2-
Saegun Kim (3092277) +7 more
core +1 more source
ChemistryEuropeSubstituted ceramidonines were synthesized by cyclization of 1‐(arylamino)anthraquinones under acidic conditions. These key intermediates were prepared either by copper‐promoted N‐arylation of 1‐aminoanthraquinone with iodoarenes or, more efficiently, by
Ahlem N. Khelf‐Maghraoui +15 more
doaj +1 more source
Crop Protection and Treatment: Studying Fungal Membrane Damage by Tetrahydroacridine Derivatives
Biomedical and Biotechnology Research JournalBackground: The widespread use of antibiotics has led to the emergence of drug-resistant strains, posing a significant challenge to global public health. Inspired by natural products, this study synthesized three series of tetrahydroacridine derivatives.
Yanhui Zhao +5 more
doaj +1 more source
The Chemical Record, EarlyView.Two decades of synthetic strategies for sulfur‐, selenium‐decorated coumarins are critically surveyed through 44 literature reports, with particular emphasis on derivatives functionalized at the C‐3 and C‐4 positions. This review reports the direct construction of the coumarin framework through cyclization processes and late‐stage functionalization of ...
Bruna R. Schneider +6 more
wiley +1 more source
, 2012 A facile palladium-catalyzed synthesis of acridines has been realized by consecutive C=C double bond formation and CN cross-coupling. A variety of functionalized acridines can be accessed from easily available o-dihalobenzenes and N-tosylhydrazones in a ...
Xiao, Qing +4 more
core +1 more source