Results 71 to 80 of about 2,191 (200)

Ceramidonines, Fused 3,9‐Diazaperylenes, and Related Compounds: From Synthesis to Physicochemical Properties and Evaluation as Inhibitors of PIM Kinases

ChemistryEurope
Substituted ceramidonines were synthesized by cyclization of 1‐(arylamino)anthraquinones under acidic conditions. These key intermediates were prepared either by copper‐promoted N‐arylation of 1‐aminoanthraquinone with iodoarenes or, more efficiently, by
Ahlem N. Khelf‐Maghraoui, Nicolas Mast, William Erb, Lionel Nauton, Pascale Moreau, Nicolas Richy, Guillaume Calvez, Yann Molard, Olivier Mongin, Jean‐Pierre Hurvois, Thierry Roisnel, Charline Piroud, Thomas Robert, Stéphane Bach, Ghenia Bentabed‐Ababsa, Florence Mongin   +15 more
doaj   +1 more source

Crop Protection and Treatment: Studying Fungal Membrane Damage by Tetrahydroacridine Derivatives

Biomedical and Biotechnology Research Journal
Background: The widespread use of antibiotics has led to the emergence of drug-resistant strains, posing a significant challenge to global public health. Inspired by natural products, this study synthesized three series of tetrahydroacridine derivatives.
Yanhui Zhao, Shuaipeng Xu, Tianhao Pang, Xueqing Zhang, Wei Liu, Buer Song   +5 more
doaj   +1 more source

AI‐enabled biomimetic flexible pressure sensors for high‐precision gait monitoring and rehabilitation assessment

FlexMat, EarlyView.
A biomimetic multilayer capacitive sensor‐integrated insole enables high‐resolution plantar pressure mapping for intelligent gait analysis. Featuring ultrahigh sensitivity, wide detection range, and long‐term stability, the system leverages AI algorithms to decode spatiotemporal pressure signals, achieving accurate recognition of postoperative ...
Yingchun Li, Yarong Ding, Kaixin Lei, Yuze Zhang, Zhenhua Lin, Jiachun Sun, Kaitai Guo, Yang Zheng, Shaozhe Tan, Xuesi Zhang, Xinyue Li, Yue Hao, Xiangning Li, Yannan Liu, Jingjing Chang   +14 more
wiley   +1 more source

Deep red to near‐infrared thermally activated delayed fluorescence conjugated polymers toward highly efficient solution‐processible deep red and near‐infrared organic light‐emitting diodes

FlexMat, EarlyView.
A series of deep red (DR) and near‐infrared (NIR) thermally activated delayed fluorescence conjugated polymers are prepared, their solution‐processible organic light‐emitting diodes exhibit DR emission with maximum external quantum efficiency (EQEmax) of 6.4%, high luminance of 4254 cd m−2 and emission peak at 678 nm, and a NIR device with EQEmax of 2 ...
Tao Wang, Hongyang Zhang, Liping Jin, Peng Tao, Yanxiang Cheng, Wai‐Yeung Wong   +5 more
wiley   +1 more source

Conjugation with Acridines Turns Nuclear Localization Sequence into Highly Active Antimicrobial Peptide

Engineering, 2015
The emergence of multidrug-resistant bacteria creates an urgent need for alternative antibiotics with new mechanisms of action. In this study, we synthesized a novel type of antimicrobial agent, Acr3-NLS, by conjugating hydrophobic acridines to the N ...
Wei Zhang, Xiaoli Yang, Jingjing Song, Xin Zheng, Jianbo Chen, Panpan Ma, Bangzhi Zhang, Rui Wang   +7 more
doaj   +1 more source

The Development of Visible-Light Organic Photocatalysts for Atom Transfer Radical Polymerization via Conjugation Extension

Molecules
This work aimed to develop organic photocatalysts (PCs) that could mediate organocatalytic atom transfer radical polymerization (O-ATRP) under visible light.
Hui Shao, Runzhi Long, Hui Xu, Pan Sun, Guangrong Wang, Yuanming Li, Saihu Liao   +6 more
doaj   +1 more source

Health Biomarkers of Pesticide Exposure in Rural Populations of Santa Fe, Argentina: Oxidative Stress and Genotoxicity

Journal of Applied Toxicology, EarlyView.
ABSTRACT The present study aimed to quantify pesticide residues in environmental matrices and plasma and to evaluate their potential effects on oxidative stress and DNA damage in rural populations of Santa Fe province. Soil and rainwater samples were collected, and biological samples and semistructured surveys were obtained from volunteers in three ...
María Priscila Dechiara, Carlina Leila Colussi, Lucía Magdalena Odetti, Damián Marino, María Fernanda Simoniello   +4 more
wiley   +1 more source

Designing Thermally Stable DNA Hydrogels via Entropically‐Driven Acridine Intercalation

Macromolecular Rapid Communications, EarlyView.
Environmental variables are shown to systematically tune the network dynamics of entropy‐driven, acridine‐based DNA‐intercalating supramolecular hydrogels. Adjusting the buffer composition, ionic identity, and salt concentration impacts electrostatic screening and counterion release of the DNA backbone, offering a powerful handle to tune elasticity and
Shaina M. Hughes, Amy M. DiVito, Patrick F. Strobel, Pearson J. J. Franz, Matthew E. Currier, Nathan J. Oldenhuis   +5 more
wiley   +1 more source

Recent Advances in Photocatalyst‐Driven Protein Labeling and Proximity Mapping

The Chemical Record, EarlyView.
Photocatalyst‐driven protein labeling and proximity mapping have rapidly advanced as powerful strategies for spatiotemporal control in complex biological environments. This review integrates recent developments across single‐electron transfer and energy transfer‐based mechanisms and highlights how catalyst design, reactive intermediates, and diffusion ...
Shinichi Sato, Kazuki Miura, Juki Nakao, Hiroyuki Nakamura   +3 more
wiley   +1 more source

Microfluidic Intracytoplasmic Sperm Injection (MICSI): A Novel Platform for Sperm Isolation, Selection, and Injection Into Oocytes

Andrology, EarlyView.
ABSTRACT Background Infertility is a pressing global health concern, affecting one in six couples worldwide. The failure rate for assisted reproductive technologies (ART) cycles remains at approximately 78%, with limited improvements often attributed to a lack of technological innovation.
Mehran Dabiri, Dale Mark Goss, Steven Alexander Vasilescu, Majid Ebrahimi Warkiani   +3 more
wiley   +1 more source