Results 61 to 70 of about 28,376 (179)

Optical spectrum of proflavine and its ions

, 2010
Motivated by possible astrophysical and biological applications we calculate visible and near UV spectral lines of proflavine (C13H11N3, 3,6-diaminoacridine) in vacuum, as well as its anion, cation, and dication.
A. Bonaca, Bauschlicher, Becke, Castro, Castro, Clemett, De Silvestri, Destree, Ehrenfreund, G. Bilalbegović, Giannozzi, Godby, Herbig, Hirata, Hobbs, Hudgins, Jain, Jenniskens, Jones, Koch, Kokalj, Le Page, Lee, Lepp, Lerman, Malloci, Malloci, Marques, Martin, Mataga, Neumann, Perdew, Pileni, Rappe, Rocca, Runge, Sarre, Sarre, Sarre, Schulman, Snow, Thaddeus, Tielens, Tozzini, Troullier, Tuairisg, Varsano, Walker, Weisman, Yabana   +49 more
core   +1 more source

Investigation of Antileishmanial Activities of Acridines Derivatives against Promastigotes and Amastigotes Form of Parasites Using Quantitative Structure Activity Relationship Analysis

, 2016
In a search of newer and potent antileishmanial (against promastigotes and amastigotes form of parasites) drug, a series of 60 variously substituted acridines derivatives were subjected to a quantitative structure activity relationship (QSAR) analysis ...
Samir CHTITA, M. Ghamali, R. Hmamouchi, B. Elidrissi, M. Bourass, M. Larif, M. Bouachrine, T. Lakhlıfı   +7 more
semanticscholar   +1 more source

A study of the feculae of Orthoptera, their specificity, and the role which the insects'mouthparts, alimentary canal, and food-habits play in their formation [PDF]

, 1962
2 láminasMany physiological studies have been carried out on different aspects of the feculae ("feces") and their formation in Orthoptera (sens. lat.).
Gangwere, S. K.
core  

G-Quadruplex Dynamics Contribute To Regulation Of Mitochondrial Gene Expression [PDF]

, 2019
Single-stranded DNA or RNA sequences rich in guanine (G) can adopt non-canonical structures known as G-quadruplexes (G4). Mitochondrial DNA (mtDNA) sequences that are predicted to form G4 are enriched on the heavy-strand and have been associated with ...
Alder, J. K., de Jesus, D., Falabella, M., Horne, W., Johnson, F. B., Kaufman, B. A., Kolesar, J. E., Maheshan, R., Pagano, P. J., Sondheimer, N., St. Croix, C. M., Sun, L., Taguichi, Y. V., Turek-Herman, Joshua R., , \u2716, Wallace, C., Wang, C., Wang, T., Xiang, Irene M., , \u2718, Yatsunyk, Liliya A.   +18 more
core   +3 more sources

A facile and efficient synthesis of 1,8-dioxodecahydroacridines derivatives catalyzed by cobalt–alanine metal complex under aqueous ethanol media

BMC Chemistry, 2019
A facile and convenient method for the synthesis of acridines and its derivatives was developed through one-pot, three-component condensation reaction of aromatic aldehydes, 5,5-dimethyl-1,3-cyclohexanedione, aryl amines or ammonium acetates in the ...
M. Mujahid Alam, Ahmed T. Mubarak, Mohammed A. Assiri, S. Merajuddin Ahmed, Ahmed M. Fouda   +4 more
doaj   +1 more source

The interactions of monomeric acridines and unsymmetrical bisacridines (UAs) with DNA duplexes: an insight provided by NMR and MD studies

Scientific Reports, 2023
Members of a novel class of anticancer compounds, exhibiting high antitumor activity, i.e. the unsymmetrical bisacridines (UAs), consist of two heteroaromatic ring systems.
Tomasz Laskowski, Michał Kosno, Witold Andrałojć, Joanna E. Frackowiak, Julia Borzyszkowska-Bukowska, Paweł Szczeblewski, Nikola Radoń, Maria Świerżewska, Anna Woźny, Ewa Paluszkiewicz, Zofia Mazerska   +10 more
doaj   +1 more source

Molecular modelling studies of binding of DACD derivatives into G-Quadruplex DNA: comparison of force field and quantum polarized ligand docking methods [PDF]

, 2012
The DNA G-qadruplexes are one of the targets being actively explored for anti-cancer therapy by inhibiting them through small molecules. This computational study was conducted to predict the binding strengths and orientations of a set of novel dimethyl ...
Cardin, Christine J., Subramanian, Arun Kumar   +1 more
core  

Synthesis, DNA-Binding and Antiproliferative Properties of Acridine and 5-Methylacridine Derivatives

Molecules, 2012
Several acridine derivatives were synthesized and their anti-proliferative activity was determined. The most active molecules were derivatives of 5-methylacridine-4-carboxylic acid. The DNA binding properties of the synthesized acridines were analyzed by
Ramon Eritja, Rubén Ferreira, Stefania Mazzini, Anna Aviñó   +3 more
doaj   +1 more source

In vitro activity of salinomycin and monensin derivatives against Trypanosoma brucei [PDF]

, 2016
Background: African trypanosomes are the causative agents of sleeping sickness in humans and nagana disease in livestock animals. As the few drugs available for treatment of the diseases have limited efficacy and produce adverse reactions, new and better
A Huczyński, A Huczyński, A Huczyński, A Huczyński, A Huczyński, A Huczyński, A Scherzad, Adam Huczyński, AH Fairlamb, D Steverding, DH Molyneux, Dietmar Steverding, E Matovu, GE Moore, H Hirumi, K Merschjohann, M Antoszczak, M Antoszczak, Michał Antoszczak, S Nwaka, SJ Collins, SV Barrett, T Baltz, V Delespaux, W Huber   +24 more
core   +1 more source

9-phenyl acridine photosensitizes A375 cells to UVA radiation

Heliyon, 2020
Acridines are an important class of bioactive molecules having varied uses. Its derivative, 9-phenylacridine (ACPH) had been found to exhibit antitumor activity both in cell lines and in vivo model.
Surajit Hansda, Gargi Ghosh, Rita Ghosh
doaj   +1 more source