Results 61 to 70 of about 3,278 (246)

Synthesis and physical properties of polyfluoro-acridines bearing perfluoroalkyl chains

, 2008
Here we describe the synthesis of polyfluoro-acridines functionalised with perfluoro-alkyl and perfluoro-alkoxy chains, obtained by Ullmann coupling reaction or aromatic nucleophilic substitution.
E. Tonelli, P. Campiglio, L. Miozzo, A. Mani, A. Papagni, M. Campione, P. Del Buttero   +6 more
core   +1 more source

A Novel Bioactive Component, Efoba, From Aged Garlic Targets CTSC to Suppress NET‐Driven Neuroinflammation and Ameliorate Secondary Brain Injury After Intracerebral Hemorrhage

Advanced Science, EarlyView.
Efoba, a novel bioactive component derived from aged garlic, confers neuroprotection against intracerebral hemorrhage. It acts on microglia to suppress CTSC release, inhibits NET‐mediated neural injury, and blocks pathological microglia‐neutrophil crosstalk. This study provides a highly promising lead compound for hemorrhagic‐stroke therapy.
Junjun Meng, Jianhua Wang, Tao Zhang, Xiaofan Fan, Jinxiu Guo, Shiyuan Zhao, Wenxue Sun, Pei Jiang   +7 more
wiley   +1 more source

Efficient and Convenient Synthesis of 1,8-Dioxodecahydroacridine Derivatives Using Cu-Doped ZnO Nanocrystalline Powder as a Catalyst under Solvent-Free Conditions

The Scientific World Journal, 2013
A simple and convenient one-step method for synthesis of acridines and their derivatives from condensation of aromatic aldehydes, cyclic diketones, and aryl amines using Cu-doped ZnO nanocrystalline powder as a catalyst is reported.
Heshmatollah Alinezhad, Sahar Mohseni Tavakkoli   +1 more
doaj   +1 more source

Correlation between anti-malarial and anti-haemozoin activities of anti-malarial compounds

Malaria Journal, 2020
Background Despite noticeable improvement in anti-malarial treatment, rapid growth of resistant malaria strains points out the need for continuous development of novel anti-malarials to fight the disastrous infection.
Dao Ngoc Hien Tam, Gehad Mohamed Tawfik, Amr Ehab El-Qushayri, Ghaleb Muhammad Mehyar, Sedralmontaha Istanbuly, Sedighe Karimzadeh, Vo Linh Tu, Ranjit Tiwari, Truong Van Dat, Phuong Thuy Viet Nguyen, Kenji Hirayama, Nguyen Tien Huy   +11 more
doaj   +1 more source

Aromatic Iodides: Synthesis and Conversion to Heterocycles

Chemistry Proceedings, 2022
Aromatic heterocycles can be found in many molecules endowed with specific properties, in particular for applications in the fields of medicinal chemistry and materials science.
Florence Mongin, William Erb, Frédéric Lassagne   +2 more
doaj   +1 more source

Magnetoelastic Cell Monitoring System for Evaluating the Effects of Surface Chemistry on the Performance of Mesenchymal Stem Cell Growth

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The recent clinical adoption of cell therapies has increased the need for more efficient, robust, and reproducible manufacturing technologies. Human mesenchymal stromal cells (hMSCs), a major component of the cell and immunotherapeutic market, remain challenging to manufacture at scale because they require surface attachment and are highly ...
William S. Skinner, Carolina Rivera‐Crespo, Eyerusalem A. Gebreyesus, Said Cifuentes, Samantha Tan, Tristen Douglas, Maribella Domenech‐Garcia, Keat Ghee Ong   +7 more
wiley   +1 more source

Pd(II)-Catalyzed One-Pot, Three-Step Route for the Synthesis of Unsymmetrical Acridines

, 2016
Unsymmetric acridines are synthesized via a one-pot amination/cyclization/aromatization reaction for the first time. With Pd(OAc)2-X-Phos as the catalyst, a series of unsymmetric acridines are obtained in moderate to excellent yields (up to 99% yield ...
Hai-Ming Guo (1395550), Hong-Ying Niu (1819324), Gui-Rong Qu (1395547), Qiao-Tian Wang (1892095), Ming-Sheng Xie (1395553), Run-Ze Mao (1479157)   +5 more
core   +1 more source

Impacts of refining Canadian partially upgraded bitumen: Fluid catalytic cracking

The Canadian Journal of Chemical Engineering, EarlyView.
Abstract In this study, we examine the fluid catalytic cracking (FCC) performance of vacuum gas oil (VGO) from partially upgraded bitumen (PUB), a novel refinery feedstock from Canadian bitumen. FCC experiments were conducted in a lab‐scale FCC unit with VGOs from two different PUBs prepared using thermal cracking and solvent deasphalting, along with ...
Yi Zhang, Anton Alvarez‐Majmutov, Rafal Gieleciak, Jinwen Chen   +3 more
wiley   +1 more source

Nucleophilic Reactions of Cyclobutenones and the Related 4,4‐Dichlorocyclobutenone Derivatives

European Journal of Organic Chemistry, EarlyView.
Cyclobutenone derivates and their 4,4‐dichloro counterparts have an uninterrupted attention as useful synthons in the synthesis of complex organic molecules. Their nucleophilic reactions remain underexplored. This review brings attention to these reactions, whose outcome is not straightforward.
Sarah J. Wright, Muhluri H. Mthombeni, Songeziwe Ntsimango   +2 more
wiley   +1 more source

Synthèse et caractérisation de bis acridines pontées en positions 2, 3 ou 4

, 2009
International audienceThe preparation of 2,2′, 3,3′ and 4,4′‐bridged bisacridines is described. The method consists in the acylation of 2m 3, or 4‐aminoacridines in acetone, as the solvent.
Galy, Jean‐pierre, Boyer, Gérard, Barbe, Jacques   +2 more
core   +1 more source