Results 121 to 130 of about 3,278 (246)

Degrees of Sulfonation: Mapping the Reactivity Landscape of Acridine and Acridone

Organics
Although sulfonated acridines and acridones are valuable scaffolds in diagnostics and materials science, to our best knowledge, there is no comprehensive study that addresses how the degree of sulfonation depends on reaction parameters. To fill this gap,
Péter Kisfaludi, Sára Spátay, Péter Huszthy, Ádám Golcs   +3 more
doaj   +1 more source

Understanding extracellular vesicles in antiaging

Periodontology 2000, EarlyView.
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad, Nathan E. Estrin, Anton Sculean, Richard J. Miron   +3 more
wiley   +1 more source

Synthesis of azepane-acridine heterocyclic adducts assisted by the catalytic influence of γ-Fe2O3@TiO2-Vitamin B1 and evaluation of their medicinal potential through in vitro antimicrobial, QSAR, and molecular docking studies

Results in Chemistry
Present work elicits synthesis of novel azepane-acridines, assisted by titania-encapsulated γFe2O3 nanoparticles supported on Vitamin B1 (γFe2O3@TiO2-Vitamin B1) as a new magnetically recyclable heterogeneous nano-catalytic system.
Shweta Potdar, Pratibha Sharma, Nikita Pal, Ashok Kumar   +3 more
doaj   +1 more source

Unprecedented Bridged Annulation Approach to the Construction of 5,6-Dihydro-4H-benzo[kl]acridines

, 2009
A general and novel “bridged annulation” methodology for the synthesis of 5,6-dihydro-4H-benzo[kl]acridines has been developed via Michael addition of a conjugate base of 9-methyl-3,4-dihydroacridin-1(2H)-one to various cyclic or acyclic α,β-unsaturated ...
Goel, Atul, Kant, Ruchir, Maulik, Prakas R., Kumar, Amit, Singh, Salil Pratap   +4 more
core   +1 more source

Large‐Scale and Cost‐Effective Fabrication of Ultra‐Thin, Biodegradable Microelectrode Arrays and Pressure Sensors Using Laser Micromachining

Advanced Materials Technologies, Volume 11, Issue 21, 6 November 2026.
A mask‐free and cost‐effective UV‐pico‐second laser‐based microfabrication method is proposed to fabricate large‐area biodegradable microelectrode arrays and pressure sensors. These devices demonstrate low impedance, good conformability, excellent biocompatibility, and rapid degradation, providing a new route for next‐generation transient electronics ...
Bhavani Prasad Yalagala, Asfand Tanwear, María Cerezo‐Sánchez, Hossein Parvizi, Morteza Amjadi, Hadi Heidari   +5 more
wiley   +1 more source

Induction of anti-Escherichia coli activity in mice by phenothiazines, benzo[a]phenothiazines and benz[c]acridines

, 1992
The abilities of 14 phenothiazines, 8 benzo[a]phenothiazines and 12 benz[c]acridines to induce anti-Escherichia coli activity in mice were compared. Pretreatment with several benzo[a]phenothiazines or benz[c]acridines protected mice from lethal infection
Fujimaki Masato, Komatsu Nobuhiko, Molnár József, Motohashi Noboru, Wada Chikako, Sakagami Hiroshi   +5 more
core  

DDX3x Regulates NINJ1 Transcription via Histone Lactylation in Sepsis Associated‐Acute Kidney Injury

Advanced Science, Volume 13, Issue 61, 3 November 2026.
This study identifies a potential therapeutic approach for sepsis‐associated acute kidney injury (SA‐AKI). We found that during SA‐AKI, reduced expression of DDX3x in renal tubular epithelial cells mediates histone delactylation, which in turn upregulates NINJ1 transcription and triggers tubular cell death. Conversely, Odetiglucan confers protection by
Hongyu Liang, Jihong Jiang, Huanxin Yin, Chunyan Liu, Hongjun Huang, Yan Luo, Minmin Zhu, Qiuyun Wang   +7 more
wiley   +1 more source

Cascade Nucleophilic Addition−Cyclic Michael Addition of Arynes and Phenols/Anilines Bearing Ortho α,β-Unsaturated Groups: Facile Synthesis of 9-Functionalized Xanthenes/Acridines

, 2016
A facile synthesis of xanthenes and acridines based on a cascade nucleophilic addition−cyclic Michael addition process of arynes and phenols/anilines substituted with α,β-unsaturated groups at the ortho positions is described.
Xian Huang (820390), Tiexin Zhang (2325250)   +1 more
core   +1 more source

An Avalanche Effect Nanomodulator Triggers Cascade Ferroptosis/Cuproptosis for Immunosuppressive Microenvironment Remodeling

Advanced Science, Volume 13, Issue 61, 3 November 2026.
A nanomodulator called L‐Arginine/lificiguat@Copper‐hollow Prussian blue@Calcium phosphate nanoparticles is constructed to launch a self‐amplifying “avalanche effect” in tumor cells. The ensuing cascade, triggered by the acidic tumor microenvironment and near‐infrared light, induces calcium overload, generates a reactive oxygen species and reactive ...
Hongmei Zhou, Caixi Yu, Guilan Xu, Lijuan Liu, Yujia Liang, Yulin Liang, He Ding, Litu Zhang, Piaoping Yang, Chen Wang   +9 more
wiley   +1 more source

Synthesis and antimicrobial activities of nitro substituted indolo[3,2-c]acridines

, 2011
906-909The efficient synthesis of biologically active 9-nitro-7-phenyl-5,6-dihydro-indolo[3,2-c]acridines 2a-e is described from the  reaction of 2,3,4,9-tetrahydro-1H-carbazol-1-one with 2-amino-5-nitro-benzophenone in acetic acid and a few ...
Prabakaran, K, Prasad, K J Rajendra, Yamuna, E   +2 more
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