Results in Chemistry, 2023 Applying the Ullmann synthesis, substituted aniline and o-halobenzoic acids are combined with potassium carbonate and copper powder to produce N- (substituted phenyl) anthranilic acids.
S. Sulthanudeen +3 more
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Synthesis and Biological Evaluation of Acridone Derivatives for Antimicrobial and Antifungal Applications [PDF]
Journal of Experimental PharmacologyAli Salman Al-Shami,1,2 Jalal Alkadsi3 1Department of Pharmacology, Faculty of Medicine, Sanaa University, Sanaa City, Republic of Yemen; 2Jiblah University for Medical and Health Science, Ibb City, Republic of Yemen; 3Department of Medicinal Chemistry ...
Al-Shami AS, Alkadsi J
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Structural and mechanistic insights into Quinolone Synthase to address its functional promiscuity [PDF]
Communications BiologyQuinolone synthase from Aegle marmelos (AmQNS) is a type III polyketide synthase that yields therapeutically effective quinolone and acridone compounds. Addressing the structural and molecular underpinnings of AmQNS and its substrate interaction in terms
Mallika Vijayanathan +7 more
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A Metallosupramolecular Receptor for Squaraine Dyes Enabling Ultrafast Dark Resonance Energy Transfer. [PDF]
Angew Chem Int Ed EnglA metallosupramolecular receptor binds squaraine dyes with high affinity and enables efficient dark resonance energy transfer (DRET) that generates bright near‐infrared emission with large pseudo‐Stokes shifts. ABSTRACT A metal‐organic cage was obtained by combining acridone‐based dipyridyl ligands with Pd2+ ions. The cage acts as a potent receptor for
Chen DW +5 more
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Wet Photolithography From Hydrogen Abstraction of a Quasi‐Orthogonal Aggregation‐Induced Emitter [PDF]
Advanced ScienceA new aggregation‐induced emission (AIE) luminogen is obtained by dimerizing acridin‐9(10H)‐one (Ac), an aggregation‐caused quenching (ACQ) effect monomer via an N─N bond and forming 9H,9′H‐[10,10′‐biacridine]‐9,9′‐dione (DiAc) with D2d symmetry.
Chen Cao +9 more
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Citrus reticulata Blanco: A Review on Chemical Composition and Biological Activities. [PDF]
Chem BiodiversThis review compiles chemical information and biological activities from 49 studies on Citrus reticulata. The fruit peels stand out for their high content of methoxylated monoterpenes and flavonoids with antioxidant, anti‐inflammatory, and antimicrobial activities.
Castro JWG +3 more
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Tuning the Excited State Character of Amine/Carbonyl Thermally Activated Delayed Fluorescence Emitters with Ring Fusion. [PDF]
ChemistryRing fusion in MR‐TADF emitters can affect the charge transfer excited state and therefore the photophysical properties. Here we investigate the effect of ring fusion in two structurally similar molecules to identify the advantages and disadvantages of this strategy.
Kalab T +3 more
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Through-space interaction enables simultaneous enhancements of <i>k</i> <sub><i>r</i></sub> and <i>k</i> <sub>RISC</sub> in highly efficient spiro-acridine based thermally activated delayed fluorescence emitter with acridone acceptor. [PDF]
Smart MolIntramolecular through‐space interaction is designed for the first time in a thermally activated delayed fluorescence emitter to pull the appropriate rotation of the acridine donor to deviate from the perpendicular orientation, which solves the common problem of insufficient FMO overlap to simultaneously enhance the radiation transition and reverse ...
Mei Y +7 more
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Molecules, 2021 A synthetic route to new heterocyclic 1,1-donor–acceptor-substituted alkenes starting with N-methyl-acridone, xanthone, and thioxanthone was investigated, leading to the acridone- and xanthone-derived products methyl 2-methoxy-2-(10-methylacridin-9 (10H)-
Tim Lippold +2 more
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Synthesis and Application in Cell Imaging of Acridone Derivatives
Applied Sciences, 2020 Tricyclic acridone derivatives have been extensively developed as antimicrobial, antimalarial, and antitumor drugs due to their broad spectrum of drug design and biological activity.
Yung-Chieh Chan +5 more
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