Results 21 to 30 of about 5,634 (238)

Acridone derivative 8a induces oxidative stress-mediated apoptosis in CCRF-CEM leukemia cells: application of metabolomics in mechanistic studies of antitumor agents. [PDF]

PLoS ONE, 2013
A new acridone derivative, 2-aminoacetamido-10-(3, 5-dimethoxy)-benzyl-9(10H)-acridone hydrochloride (named 8a) synthesized in our lab shows potent antitumor activity, but the mechanism of action remains unclear.
Yini Wang, Dan Gao, Zhe Chen, Shangfu Li, Chunmei Gao, Deliang Cao, Feng Liu, Hongxia Liu, Yuyang Jiang   +8 more
doaj   +1 more source

Fermentative N-Methylanthranilate Production by Engineered Corynebacterium glutamicum

Microorganisms, 2020
The N-functionalized amino acid N-methylanthranilate is an important precursor for bioactive compounds such as anticancer acridone alkaloids, the antinociceptive alkaloid O-isopropyl N-methylanthranilate, the flavor compound O-methyl-N-methylanthranilate,
Tatjana Walter, Nour Al Medani, Arthur Burgardt, Katarina Cankar, Lenny Ferrer, Anastasia Kerbs, Jin-Ho Lee, Melanie Mindt, Joe Max Risse, Volker F. Wendisch   +9 more
doaj   +1 more source

Acridone and quinacridone derivatives with carbazole or phenoxazine substituents: synthesis, electrochemistry, photophysics and application as TADF electroluminophores

Journal of Materials Chemistry C, 2022
Six acridone (quinacridone) derivatives containing either carbazole or phenoxazine substituents were designed and synthesized with the aim of elucidating the effect of the donor (D) and acceptor (A) linking pattern...
I. Kulszewicz-Bajer, M. Guzauskas, M. Makowska-Janusik, M. Zagórska, Malek Mahmoudi, J. Gražulevičius, A. Pron, D. Volyniuk   +7 more
semanticscholar   +1 more source

RETRACTED: An acridone-derived fluorescent off-on probe for detection and in vivo imaging of nitroreductase

Frontiers in Materials, 2023
Understanding the functions of enzymes in various physiological processes is important, but the design of signaling probes for fast analysis of enzymatic activity is particularly challenging.
Meicen Liu, Guanyu Chen, Guanyu Chen, Lilan Xu, Lilan Xu, Tingting Chen, Tingting Chen, Wenqian Chen, Wenqian Chen, Jinghua Chen, Jinghua Chen, Xi Zhang   +11 more
doaj   +1 more source

Two New Acridone Alkaloids from Glycosmis macrantha

Molecules, 2011
Extraction and chromatographic separation of the extracts of dried stem barks of Glycosmis macrantha lead to isolation of two new acridone alkaloids, macranthanine (1) and 7-hydroxynoracronycine (2), and a known acridone, atalaphyllidine (3).
Abdah Md Akim, Mohd Aspollah Sukari, Muhammad Aizat Mohd Amin, Mawardi Rahmani, Gwendoline Cheng Lian Ee, Najihah Mohd Hashim, Maizatul Akmal Yahayu   +6 more
doaj   +1 more source

‘Acridines’ as New Horizons in Antifungal Treatment

Molecules, 2020
Frequent fungal infections in immunocompromised patients and mortality due to invasive mycosis are important clinical problems. Opportunistic pathogenic Candida species remain one of the leading causes of systemic mycosis worldwide.
Iwona Gabriel
doaj   +1 more source

The role of cycloferon in the treatment of chronic Helicobacter pyloriinduced gastritis with gastric erosions associated with Epstein – Barr virus

Лечащий Врач, 2022
Evaluation of the effectiveness of cycloferon when used in complex therapy and for the prevention of chronic Helicobacter pyloriinduced gastritis with gastric erosions associated with Epstein – Barr virus.
T. E. Afanasenkova, E. E. Dubskaya
doaj   +1 more source

Synthesis, biological evaluation, molecular docking and in silico ADMET screening studies of novel isoxazoline derivatives from acridone

Arabian Journal of Chemistry, 2021
A series of new acridone derivatives from isoxazoline (2a-l) were synthesized via 1,3-dipolar cycloaddition reaction between a variety of aryl nitrile oxides and N-allyl acridones using simple and efficient methods.
Mohammed Aarjane, S. Slassi, A. Ghaleb, B. Tazi, A. Amine   +4 more
semanticscholar   +1 more source

Microwave-Assisted Regioselective Synthesis and 2D-NMR Studies of New 1,2,3-Triazole Compounds Derived from Acridone

Journal of Chemistry, 2021
A simple and mild protocol towards the synthesis of new 1,2,3-triazole compounds derived from acridone has been developed via regiospecific 1,3-dipolar cycloaddition reaction between 10-(prop-2-yn-1-yl)acridone derivatives and aromatic azides using CuI ...
Mohammed Aarjane, Siham Slassi, Bouchra Tazi, Amina Amine   +3 more
doaj   +1 more source

Methyltransferases from Ruta graveolens L.: Molecular Biology and Biochemistry [PDF]

, 2005
The common rue, Ruta graveolens L., is an aromatic plant. It contains acridone alkaloids, furoquinolines, coumarins, and numerous volatile compounds with antimicrobial and allelopathic activity.
Burga, Laura, Matern, Ulrich (Prof. Dr.)
core   +1 more source