Synthesis of Xanthones, Thioxanthones and Acridones by a Metal-Free Photocatalytic Oxidation Using Visible Light and Molecular Oxygen [PDF]
Molecules, 2021 9H-Xanthenes, 9H-thioxanthenes and 9,10-dihydroacridines can be easily oxidized to the corresponding xanthones, thioxanthones and acridones, respectively, by a simple photo-oxidation procedure carried out using molecular oxygen as oxidant under the ...
Rafael Chinchilla
exaly +6 more sources
Multi-Target Actions of Acridones from Atalantia monophylla towards Alzheimer’s Pathogenesis and Their Pharmacokinetic Properties [PDF]
Pharmaceuticals, 2021 Ten acridones isolated from Atalantia monophylla were evaluated for effects on Alzheimer’s disease pathogenesis including antioxidant effects, acetylcholinesterase (AChE) inhibition, prevention of beta-amyloid (Aβ) aggregation and neuroprotection.
Pitchayakarn Takomthong +8 more
doaj +3 more sources
Acridones as promising drug candidates against Oropouche virus [PDF]
Current Research in Microbial SciencesOropouche virus (OROV) is an emerging vector-borne arbovirus found in South America that causes Oropouche fever, a febrile infection similar to dengue fever.
Marielena Vogel Saivish +16 more
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Application of Lanthanide Shift Reagent to the 1H-NMR Assignments of Acridone Alkaloids [PDF]
Molecules, 2020 This study investigates the application of the paramagnetic shift reagent tris(dipivaloylmethanato)-europium(III) in NMR spectral studies of permethoxyacridone alkaloids (1–3) and pyranoacridone alkaloids (4–6).
Sio-Hong Lam +5 more
doaj +2 more sources
Multi spectroscopic and molecular simulation studies of propyl acridone binding to calf thymus DNA in the presence of electromagnetic force [PDF]
BioImpacts, 2023 Introduction: Here, the interaction behavior between propyl acridones (PA) and calf thymus DNA (ct-DNA) has been investigated to attain the features of the binding behavior of PA with ct-DNA, which includes specific binding sites, modes, and constants ...
Atena Sharifi-Rad +9 more
doaj +2 more sources
Building Accurate Intracellular Polarity Maps through Multiparametric Microscopy [PDF]
Methods and Protocols, 2020 The precise knowledge of intracellular polarity, a physiological parameter that involves complex and intertwined intracellular mechanisms, may be relevant in the study of important diseases like cancer or Alzheimer’s.
M. Carmen Gonzalez-Garcia +3 more
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An Overview of the Medicinally Important Plant Type III PKS Derived Polyketides [PDF]
Frontiers in Plant Science, 2021 Plants produce interesting secondary metabolites that are a valuable source of both medicines for human use, along with significant advantages for the manufacturer species.
Renu Bisht +3 more
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Integrated Analytical Tools for Accessing Acridones and Unrelated Phenylacrylamides from Swinglea glutinosa [PDF]
Molecules, 2019 In natural product studies, the purification of metabolites is an important challenge. To accelerate this step, alternatives such as integrated analytical tools should be employed.
Ana Calheiros de Carvalho +5 more
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Synthesis of acridone derivatives via heterologous expression of a plant type III polyketide synthase in Escherichia coli [PDF]
Microbial Cell Factories, 2020 Background Acridone alkaloids are heterocyclic compounds that exhibit a broad-range of pharmaceutical and chemotherapeutic activities, including anticancer, antiviral, anti-inflammatory, antimalarial, and antimicrobial effects. Certain plant species such
Gyu-Sik Choi +3 more
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Synthesis and Biological Evaluation of Acridone Derivatives for Antimicrobial and Antifungal Applications [PDF]
Journal of Experimental PharmacologyAli Salman Al-Shami,1,2 Jalal Alkadsi3 1Department of Pharmacology, Faculty of Medicine, Sanaa University, Sanaa City, Republic of Yemen; 2Jiblah University for Medical and Health Science, Ibb City, Republic of Yemen; 3Department of Medicinal Chemistry ...
Al-Shami AS, Alkadsi J
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