Results 21 to 30 of about 664 (168)
Development of Mild Palladium-Catalyzed N-Arylation of Ortho-Acylanilines in Rhamnolipid Micellar System. [PDF]
Aqueous micellar catalysis using industrially sourced rhamnolipids enables efficient Pd‐catalyzed N‐arylation of o‐acylanilines at 40°C. This surfactant‐driven system offers a sustainable and more efficient alternative to organic solvents, combining broad substrate scope, low catalyst loading, and enhanced energy efficiency.
Herczegh AR +3 more
europepmc +2 more sources
Benzylic systems such as 9H-xanthenes, 9H-thioxanthenes and 9,10-dihydroacridines can be easily oxidized to the corresponding xanthones, thioxanthones or acridones, respectively, in deep eutectic solvents by a visible blue light-promoted photooxidation ...
Sarah-Jayne Burlingham +3 more
doaj +1 more source
Artur Silva’s research group has a long history in the field of medicinal chemistry. The development of new synthetic methods for oxygen (mostly polyphenols, e.g., 2- and 3-styrylchromones, xanthones, flavones) and nitrogen (e.g., pyrazoles, triazoles ...
Joana L. C. Sousa +2 more
doaj +1 more source
Engineered biosynthesis of plant polyketides by type III polyketide synthases in microorganisms
Plant specialized metabolites occupy unique therapeutic niches in human medicine. A large family of plant specialized metabolites, namely plant polyketides, exhibit diverse and remarkable pharmaceutical properties and thereby great biomanufacturing ...
Chang Liu, Sijin Li
doaj +1 more source
One-Pot Synthesis of 1‑Hydroxyacridones from para-Quinols and ortho-Methoxycarbonylaryl Isocyanates
A variety of substituted acridones were synthesized via a one-pot, metal-free cascade reaction. In this event, the DBU-mediated addition between quinols and ortho-methoxycarbonylaryl isocyanates formed a bicyclic oxazolidinone, followed by a sequence of ...
Jinzhu Zhang (1934107) +9 more
core +4 more sources
Applying the Ullmann synthesis, substituted aniline and o-halobenzoic acids are combined with potassium carbonate and copper powder to produce N- (substituted phenyl) anthranilic acids.
S. Sulthanudeen +3 more
doaj +1 more source
Aromatic Iodides: Synthesis and Conversion to Heterocycles
Aromatic heterocycles can be found in many molecules endowed with specific properties, in particular for applications in the fields of medicinal chemistry and materials science.
Florence Mongin +2 more
doaj +1 more source
Investigation of Dual Stage Acridones as a Potent Malaria Treatment [PDF]
The need for potent antimalarials to prevent the emergence of drug resistant Plasmodium falciparum is urgent. Discovery of novel acridone chemotypes have shown promise for a new antimalarial drug treatment.
Huezo, Stephanie
core +1 more source
‘Acridines’ as New Horizons in Antifungal Treatment
Frequent fungal infections in immunocompromised patients and mortality due to invasive mycosis are important clinical problems. Opportunistic pathogenic Candida species remain one of the leading causes of systemic mycosis worldwide.
Iwona Gabriel
doaj +1 more source

