Results 21 to 30 of about 601 (168)

Development of Mild Palladium-Catalyzed N-Arylation of Ortho-Acylanilines in Rhamnolipid Micellar System. [PDF]

ChemSusChem
Aqueous micellar catalysis using industrially sourced rhamnolipids enables efficient Pd‐catalyzed N‐arylation of o‐acylanilines at 40°C. This surfactant‐driven system offers a sustainable and more efficient alternative to organic solvents, combining broad substrate scope, low catalyst loading, and enhanced energy efficiency.
Herczegh AR, Kollár PR, Lehmann J, Novák Z.   +3 more
europepmc   +2 more sources

New Acridone- and (Thio)Xanthone-Derived 1,1-Donor–Acceptor-Substituted Alkenes: pH-Dependent Fluorescence and Unusual Photooxygenation Properties

Molecules, 2021
A synthetic route to new heterocyclic 1,1-donor–acceptor-substituted alkenes starting with N-methyl-acridone, xanthone, and thioxanthone was investigated, leading to the acridone- and xanthone-derived products methyl 2-methoxy-2-(10-methylacridin-9 (10H)-
Tim Lippold, Jörg M. Neudörfl, Axel Griesbeck   +2 more
doaj   +1 more source

Visible light-promoted metal-free aerobic photooxidation of xanthenes, thioxanthenes and dihydroacridines in deep eutectic solvents

Tetrahedron Green Chem, 2023
Benzylic systems such as 9H-xanthenes, 9H-thioxanthenes and 9,10-dihydroacridines can be easily oxidized to the corresponding xanthones, thioxanthones or acridones, respectively, in deep eutectic solvents by a visible blue light-promoted photooxidation ...
Sarah-Jayne Burlingham, Alejandro Torregrosa-Chinillach, Diego A. Alonso, Rafael Chinchilla   +3 more
doaj   +1 more source

Drug Discovery Based on Oxygen and Nitrogen (Non-)Heterocyclic Compounds Developed @LAQV–REQUIMTE/Aveiro

Pharmaceuticals, 2023
Artur Silva’s research group has a long history in the field of medicinal chemistry. The development of new synthetic methods for oxygen (mostly polyphenols, e.g., 2- and 3-styrylchromones, xanthones, flavones) and nitrogen (e.g., pyrazoles, triazoles ...
Joana L. C. Sousa, Hélio M. T. Albuquerque, Artur M. S. Silva   +2 more
doaj   +1 more source

Engineered biosynthesis of plant polyketides by type III polyketide synthases in microorganisms

Frontiers in Bioengineering and Biotechnology, 2022
Plant specialized metabolites occupy unique therapeutic niches in human medicine. A large family of plant specialized metabolites, namely plant polyketides, exhibit diverse and remarkable pharmaceutical properties and thereby great biomanufacturing ...
Chang Liu, Sijin Li
doaj   +1 more source

Novel acridone derivatives probed using DFT, including design, synthesis, characterization with anti-oxidant and anti-mitotic screening

Results in Chemistry, 2023
Applying the Ullmann synthesis, substituted aniline and o-halobenzoic acids are combined with potassium carbonate and copper powder to produce N- (substituted phenyl) anthranilic acids.
S. Sulthanudeen, Predhanekar Mohamed Imran, M. Selvakumaran, Attar Kubaib   +3 more
doaj   +1 more source

Aromatic Iodides: Synthesis and Conversion to Heterocycles

Chemistry Proceedings, 2022
Aromatic heterocycles can be found in many molecules endowed with specific properties, in particular for applications in the fields of medicinal chemistry and materials science.
Florence Mongin, William Erb, Frédéric Lassagne   +2 more
doaj   +1 more source

Discovery and Structural Optimization of Acridones as Broad-Spectrum Antimalarials. [PDF]

J Med Chem, 2019
Malaria remains one of the deadliest diseases in the world today. Novel chemoprophylactic and chemotherapeutic antimalarials are needed to support the renewed eradication agenda.
Dodean RA, Kancharla P, Li Y, Melendez V, Read L, Bane CE, Vesely B, Kreishman-Deitrick M, Black C, Li Q, Sciotti RJ, Olmeda R, Luong TL, Gaona H, Potter B, Sousa J, Marcsisin S, Caridha D, Xie L, Vuong C, Zeng Q, Zhang J, Zhang P, Lin H, Butler K, Roncal N, Gaynor-Ohnstad L, Leed SE, Nolan C, Huezo SJ, Rasmussen SA, Stephens MT, Tan JC, Cooper RA, Smilkstein MJ, Pou S, Winter RW, Riscoe MK, Kelly JX.   +38 more
europepmc   +2 more sources

Ueber Acridon [PDF]

Justus Liebigs Annalen der Chemie, 1893
n ...
Graebe, C., Lagodzinski, K.
openaire   +1 more source

Transformation of acridone synthase to chalcone synthase [PDF]

FEBS Letters, 2001
Acridone synthase (ACS) and chalcone synthase (CHS) catalyse the pivotal reactions in the formation of acridone alkaloids or flavonoids. While acridone alkaloids are confined almost exclusively to the Rutaceae, flavonoids occur abundantly in all seed‐bearing plants.
Lukačin, Richard, Schreiner, Stephan, Matern, Ulrich   +2 more
openaire   +2 more sources