Results 31 to 40 of about 664 (168)

A Multi‐Stimuli Transformational Network of Benzil‐Based Pd(II) Assemblies

Angewandte Chemie, Volume 138, Issue 36, 1 September 2026.
Incorporation of a flexible and chemically reactive benzil backbone into the ligand structure allows it to access multiple conformations, enabling the formation of diverse homo‐ and heteroleptic Pd(II) assemblies with different nuclearities and topologies.
Zhiwei Zeng, A. Priscila Gia, Alexander S. Mikherdov, Mert Acar, Björn Schmidt, Guido H. Clever   +5 more
wiley   +2 more sources

Functionalization of 4-bromobenzo[c][2,7]naphthyridine via regioselective direct ring metalation. A novel approach to analogues of pyridoacridine alkaloids

Beilstein Journal of Organic Chemistry, 2019
Readily available 4-bromobenzo[c][2,7]naphthyridine undergoes regioselective direct ring metalation at C-5 with TMPMgCl∙LiCl at −40 °C. Quenching with various electrophiles gives a broad range of 5-substituted products, which are building blocks for the ...
Benedikt C. Melzer, Alois Plodek, Franz Bracher   +2 more
doaj   +1 more source

Coupled Excited-State Dynamics in N-Substituted 2-Methoxy-9-Acridones

Frontiers in Chemistry, 2019
Fluorophores of the acridone family have been widely employed in many applications, such as DNA sequencing, the detection of biomolecules, and the monitoring of enzymatic systems, as well as being the bases of intracellular sensors and even antitumoral ...
M. Carmen Gonzalez-Garcia, Pilar Herrero-Foncubierta, Pilar Herrero-Foncubierta, Silvia Castro, Sandra Resa, Jose M. Alvarez-Pez, Delia Miguel, Juan M. Cuerva, Emilio Garcia-Fernandez, Angel Orte   +9 more
doaj   +1 more source

Discovery and Structural Optimization of Acridones as Broad-Spectrum Antimalarials. [PDF]

J Med Chem, 2019
Malaria remains one of the deadliest diseases in the world today. Novel chemoprophylactic and chemotherapeutic antimalarials are needed to support the renewed eradication agenda.
Dodean RA, Kancharla P, Li Y, Melendez V, Read L, Bane CE, Vesely B, Kreishman-Deitrick M, Black C, Li Q, Sciotti RJ, Olmeda R, Luong TL, Gaona H, Potter B, Sousa J, Marcsisin S, Caridha D, Xie L, Vuong C, Zeng Q, Zhang J, Zhang P, Lin H, Butler K, Roncal N, Gaynor-Ohnstad L, Leed SE, Nolan C, Huezo SJ, Rasmussen SA, Stephens MT, Tan JC, Cooper RA, Smilkstein MJ, Pou S, Winter RW, Riscoe MK, Kelly JX.   +38 more
europepmc   +2 more sources

Color‐Pure Organic Luminophores: Characteristics, Definitions, Physical Basis and Fundamental Design Principles

Angewandte Chemie, Volume 138, Issue 30, 20 July 2026.
Color‐pure all‐organic emitters, i.e., with narrow spectral characteristics, are intensively studied for high‐definition organic LEDs and multi‐color bioimaging. In order to guide targeted materials design, this educative review discusses spectral characteristics, proper definitions and units, and the physical basis of spectral broadening, to distill ...
Johannes Gierschner, Sunwu Song, Siyang Feng, Liangxuan Wang, Miguel Ródenas, Begoña Milián‐Medina, Min Sang Kwon   +6 more
wiley   +2 more sources

Transformation of acridone synthase to chalcone synthase [PDF]

FEBS Letters, 2001
Acridone synthase (ACS) and chalcone synthase (CHS) catalyse the pivotal reactions in the formation of acridone alkaloids or flavonoids. While acridone alkaloids are confined almost exclusively to the Rutaceae, flavonoids occur abundantly in all seed‐bearing plants.
Lukačin, Richard, Schreiner, Stephan, Matern, Ulrich   +2 more
openaire   +2 more sources

Palladium/Copper Co-catalyzed Oxidative C–H/C–H Carbonylation of Diphenylamines: A Way To Access Acridones

, 2016
An efficient palladium/copper co-catalyzed oxidative double C­(sp2)–H functionalization/carbonylation of diphenylamines for synthesis of acridones has been developed. This method utilizes readily available starting materials and mild reaction conditions.
Renyi Shi (3594302), Jiangwei Wen (734862), Shan Tang (1600243), Aiwen Lei (1425289), Fan Zhang (46132)   +4 more
core   +1 more source

Design, Synthesis, and Evaluation of 10-N-Substituted Acridones as Novel Chemosensitizers in Plasmodium falciparum [PDF]

, 2007
A series of novel 10-N-substituted acridones, bearing alkyl side chains with tertiary amine groups at the terminal position, were designed, synthesized, and evaluated for the ability to enhance the potency of quinoline drugs against multidrug-resistant ...
M. J. Smilkstein, M. Riscoe, Hinrichs, David J., D. J. Hinrichs, R. A. Cooper, K. D. Lane, Winter, Rolf, Cooper, Roland A., R. A. Johnson, Smilkstein, Martin J., Kelly, Jane X., R. Winter, Johnson, Robert A., Janowsky, Aaron, R. A. Dodean, A. Janowsky, Riscoe, Michael, J. X. Kelly, Lane, Kristin D., Dodean, Rozalia A.   +19 more
core   +1 more source

Ruta graveolens L. in Evidence‐Based Phytotherapy: Pharmacological Activities, Bioactive Compounds and Safety

Phytotherapy Research, EarlyView.
Graphical representation of ethnomedical uses, major bioactive compounds, pharmacological potential and toxicological risks of Ruta graveolens L. ABSTRACT Ruta graveolens L. is widely used in traditional European, Asian, African, and South American medicine for digestive, nervous, cardiovascular, respiratory, and reproductive disorders.
Tetiana Serhiienko, Victoriya Georgiyants, Liudas Ivanauskas, Olha Mykhailenko   +3 more
wiley   +1 more source

Chemical Metabolomics: Chemical Biology Tools for Advanced Metabolism Investigations

Angewandte Chemie, Volume 138, Issue 23, 1 June 2026.
The human metabolism has been investigated for several millennia. The metabolome is known for a high complexity due to a large number of different metabolites that are present at different concentrations. Metabolomics has been developed as a field to investigate the entire human metabolome and to elucidate disease development mechanisms.
Alejandro Torregrosa‐Chinillach, Ioanna Tsiara, Wawrzyniec Haberek, Weifeng Lin, Daniel Globisch   +4 more
wiley   +2 more sources