Results 31 to 40 of about 601 (168)
Chemical Metabolomics: Chemical Biology Tools for Advanced Metabolism Investigations
Angewandte Chemie, Volume 138, Issue 23, 1 June 2026.The human metabolism has been investigated for several millennia. The metabolome is known for a high complexity due to a large number of different metabolites that are present at different concentrations. Metabolomics has been developed as a field to investigate the entire human metabolome and to elucidate disease development mechanisms.
Alejandro Torregrosa‐Chinillach +4 more
wiley +2 more sources
Beilstein Journal of Organic Chemistry, 2019 Readily available 4-bromobenzo[c][2,7]naphthyridine undergoes regioselective direct ring metalation at C-5 with TMPMgCl∙LiCl at −40 °C. Quenching with various electrophiles gives a broad range of 5-substituted products, which are building blocks for the ...
Benedikt C. Melzer +2 more
doaj +1 more source
Investigation of Dual Stage Acridones as a Potent Malaria Treatment
, 2015 The need for potent antimalarials to prevent the emergence of drug resistant Plasmodium falciparum is urgent. Discovery of novel acridone chemotypes have shown promise for a new antimalarial drug treatment.
Huezo, Stephanie
core +1 more source
Angewandte Chemie, Volume 138, Issue 11, 9 March 2026.A metallosupramolecular receptor binds squaraine dyes with high affinity and enables efficient dark resonance energy transfer (DRET) that generates bright near‐infrared emission with large pseudo‐Stokes shifts. ABSTRACT A metal‐organic cage was obtained by combining acridone‐based dipyridyl ligands with Pd2+ ions. The cage acts as a potent receptor for
Damien W. Chen +5 more
wiley +2 more sources
One-Pot Synthesis of 1‑Hydroxyacridones from para-Quinols and ortho-Methoxycarbonylaryl Isocyanates
, 2020 A variety of substituted acridones were synthesized via a one-pot, metal-free cascade reaction. In this event, the DBU-mediated addition between quinols and ortho-methoxycarbonylaryl isocyanates formed a bicyclic oxazolidinone, followed by a sequence of ...
Jiahui Lian +19 more
core +4 more sources
Angewandte Chemie International Edition, EarlyView.Color‐pure all‐organic emitters, i.e., with narrow spectral characteristics, are intensively studied for high‐definition organic LEDs and multi‐color bioimaging. In order to guide targeted materials design, this educative review discusses spectral characteristics, proper definitions and units, and the physical basis of spectral broadening, to distill ...
Johannes Gierschner +6 more
wiley +1 more source
ChemEngineeringIn this study, we investigated the impact of incorporating energetic substituents such as –NO2, –NH2, –Cl, –F, N-methyl-N-nitro (CH3–N–NO2), and picryl on the detonation performance and stability of acridone-based compounds.
Jelena Tamuliene, Jonas Sarlauskas
doaj +1 more source
N‐Aryl Acridone Derivatives as Effective Catalysts for Energy Transfer Reactions
Chemistry – A European Journal, EarlyView.Acridones derivatives have high triplet energy, are simple accessible, and could be used in challenging [2+2] ENT reactions. ABSTRACT Organic photocatalysts capable of promoting high‐energy triplet energy transfer (EnT) remain limited, particularly for demanding [2+2] photocycloaddition reactions.
Francesco Calogero +8 more
wiley +1 more source
Chemistry – A European Journal, EarlyView.Quinolin‐4‐ones were converted to chloroquinolinium salts, allowing formation of axially chiral aminoquinolinium salts via an enantioretentive SNAr reaction with a variety of amine nucleophiles. The salts have a high rotational barrier, with a racemization half‐life of ∼1000s of years.
Darren Holmes +5 more
wiley +1 more source
, 2016 An efficient palladium/copper co-catalyzed oxidative double C(sp2)–H functionalization/carbonylation of diphenylamines for synthesis of acridones has been developed. This method utilizes readily available starting materials and mild reaction conditions.
Renyi Shi (3594302) +4 more
core +1 more source