Results 11 to 20 of about 352 (121)
Synthesis and Biological Evaluation of Acridone Derivatives for Antimicrobial and Antifungal Applications [PDF]
Journal of Experimental PharmacologyAli Salman Al-Shami,1,2 Jalal Alkadsi3 1Department of Pharmacology, Faculty of Medicine, Sanaa University, Sanaa City, Republic of Yemen; 2Jiblah University for Medical and Health Science, Ibb City, Republic of Yemen; 3Department of Medicinal Chemistry ...
Al-Shami AS, Alkadsi J
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Assessment of DNA Topoisomerase I Unwinding Activity, Radical Scavenging Capacity, and Inhibition of Breast Cancer Cell Viability of N-alkyl-acridones and N,N′-dialkyl-9,9′-biacridylidenes [PDF]
Biomolecules, 2019 The anticancer activity of acridone derivatives has attracted increasing interest, therefore, a variety of substituted analogs belonging to this family have been developed and evaluated for their anti-cancer properties.
Marios G. Krokidis +9 more
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Coupled Excited-State Dynamics in N-Substituted 2-Methoxy-9-Acridones [PDF]
Frontiers in Chemistry, 2019 Fluorophores of the acridone family have been widely employed in many applications, such as DNA sequencing, the detection of biomolecules, and the monitoring of enzymatic systems, as well as being the bases of intracellular sensors and even antitumoral ...
M. Carmen Gonzalez-Garcia +9 more
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Molecules, 2021 A synthetic route to new heterocyclic 1,1-donor–acceptor-substituted alkenes starting with N-methyl-acridone, xanthone, and thioxanthone was investigated, leading to the acridone- and xanthone-derived products methyl 2-methoxy-2-(10-methylacridin-9 (10H)-
Tim Lippold +2 more
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Tetrahedron Green Chem, 2023 Benzylic systems such as 9H-xanthenes, 9H-thioxanthenes and 9,10-dihydroacridines can be easily oxidized to the corresponding xanthones, thioxanthones or acridones, respectively, in deep eutectic solvents by a visible blue light-promoted photooxidation ...
Sarah-Jayne Burlingham +3 more
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Pharmaceuticals, 2023 Artur Silva’s research group has a long history in the field of medicinal chemistry. The development of new synthetic methods for oxygen (mostly polyphenols, e.g., 2- and 3-styrylchromones, xanthones, flavones) and nitrogen (e.g., pyrazoles, triazoles ...
Joana L. C. Sousa +2 more
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Tuning the Excited State Character of Amine/Carbonyl Thermally Activated Delayed Fluorescence Emitters with Ring Fusion. [PDF]
ChemistryRing fusion in MR‐TADF emitters can affect the charge transfer excited state and therefore the photophysical properties. Here we investigate the effect of ring fusion in two structurally similar molecules to identify the advantages and disadvantages of this strategy.
Kalab T +3 more
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Engineered biosynthesis of plant polyketides by type III polyketide synthases in microorganisms
Frontiers in Bioengineering and Biotechnology, 2022 Plant specialized metabolites occupy unique therapeutic niches in human medicine. A large family of plant specialized metabolites, namely plant polyketides, exhibit diverse and remarkable pharmaceutical properties and thereby great biomanufacturing ...
Chang Liu, Sijin Li
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Results in Chemistry, 2023 Applying the Ullmann synthesis, substituted aniline and o-halobenzoic acids are combined with potassium carbonate and copper powder to produce N- (substituted phenyl) anthranilic acids.
S. Sulthanudeen +3 more
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Aromatic Iodides: Synthesis and Conversion to Heterocycles
Chemistry Proceedings, 2022 Aromatic heterocycles can be found in many molecules endowed with specific properties, in particular for applications in the fields of medicinal chemistry and materials science.
Florence Mongin +2 more
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