Results 61 to 70 of about 2,622 (202)

Integrative Insights Into DYRK1A From Molecular Function to Therapeutic Advancement

Chemical Biology &Drug Design, Volume 108, Issue 1, July 2026.
At the center the 3D structure of DYRK1A has been displayed. The dual‐function of DYRK1A involved in cancer and neurodegeneration, i.e., its overexpression drives Down syndrome, neurodegenerative disease etc., and underexpression causes intellectual disability, seizures, etc.
Sampriti Paul, Sonal Dubey, Prashant Tiwari   +2 more
wiley   +1 more source

10-(2-Biotinyloxyethyl)-9-acridone. A novel fluorescent label for (strept)avidin-biotin based assays

, 2006
A novel biotinylated fluorophore, 10-(2-biotinyloxyethyl)-9-acridone 3 has been synthesized and its fluorescent properties were examined in the presence and absence of avidin or streptavidin.
Papadopoulos, K., Agiamarnioti, K., Triantis, T., Scorilas, A.   +3 more
core   +1 more source

Acridone Alkaloids and Coumarins from the Stem Bark of Citropsis articulata (Rutaceae)

, 2010
Meva'a LM, Songue JL, Wansi J, et al. Acridone Alkaloids and Coumarins from the Stem Bark of Citropsis articulata (Rutaceae). Zeitschrift für Naturforschung B.
Songue, Jules Lobe, Waffo, Alain Francois Kamdem, Etienne Dongo, Jules Lobe Songue, Norbert Sewald, Mpondo, Theophile Ngando, Sewald, Norbert ; https://orcid.org/, Jean Duplex Wansi, Dongo, Etienne, Alain Francois Kamdem Waffo, Wansi, Jean, Theophile Ngando Mpondo, Meva'a, Luc Mbaze, Luc Mbaze Meva'a   +13 more
core   +1 more source

Phenothiazine‑, Dihydroacridine‑, and Acridone-Based Boron Difluoride Complexes: Synthesis and Structure–Property Relationships

, 2023
Boron difluoride complexes of phenothiazine, 9,10-dihydroacridine, and acridone derivatives with a pyridyl group were synthesized. Their structures, dynamic conformational behaviors, and photophysical properties, including solid-state fluorescence, were ...
Koji Yamamoto (505190), Satoki Kanamori (14676536), Wakana Imai (14676533), Yosuke Nakamura (1528330)   +3 more
core   +1 more source

Acridone alkaloids. X. 13C-Nuclear magnetic resonance spectra of acridone alkaloids.

Chemical and Pharmaceutical Bulletin, 1983
The 13C-nuclear magnetic resonance spectra of twenty-seven acridone alkaloids including angular pyrano [2, 3-c] acridones and linear pyrano [3, 2-b] acridones have been analyzed and assigned. The information should be useful for the structure elucidation of new acridone alkaloids.
FURUKAWA, HIROSHI, YOGO, MOTOI, WU, TIANSHUNG   +2 more
openaire   +2 more sources

Redetermination and absolute configuration of atalaphylline

Acta Crystallographica Section E, 2010
The title acridone alkaloid [systematic name: 1,3,5-trihydroxy-2,4-bis(3-methylbut-2-enyl)acridin-9(10H)-one], C23H25NO4, has previously been reported as crystallizing in the chiral orthorhombic space group P212121 [Chantrapromma et al. (2010).
Hoong-Kun Fun, Chin Sing Yeap, Suchada Chantrapromma   +2 more
doaj   +1 more source

Application of Lanthanide Shift Reagent to the ¹H-NMR Assignments of Acridone Alkaloids

Molecules, 2020
This study investigates the application of the paramagnetic shift reagent tris(dipivaloylmethanato)-europium(III) in NMR spectral studies of permethoxyacridone alkaloids (1–3) and pyranoacridone alkaloids (4–6).
Sio-Hong Lam, Hsin-Yi Hung, Ping-Chung Kuo, Daih-Huang Kuo, Fu-An Chen, Tian-Shung Wu   +5 more
doaj   +1 more source

SYNTHESIS AND ANTINEOPLASTIC ACTIVITY OF CERTAIN TRIAZENE AND TRIAZENO-ACRIDINE COMBILEXIN DERIVATIVES [PDF]

Bulletin of Pharmaceutical Sciences. Assiut University, 2007
Four series of bifunctional ligands have been synthesized as DNA-binding combilexins. These novel agents contain a triazenobenzene sulfonamide linker moiety that is attached to an intercalating acridine or acridone chromophore by a functionalized amide ...
Noha Amin, Nagwa Abdel Gawad, Mohammed Mohammed, Hanan Georgey, Samir Aly   +4 more
doaj   +1 more source

Acridone alkaloids from Zanthoxylum zanthoxyloides exhibit in vitro anti-Candida, anti-biofilm and antifungal-resistance-modifying activities against drug-Resistant Candida albicans, Candida glabrata and other non-albicans Candida species

Results in Chemistry
Candida infections pose a growing global health threat, with high mortality rates driven by multidrug-resistant (MDR) strains, and a limited number of antifungals in the pipeline.
Benjamin Kingsley Harley, Maudesta Opoku, Theophilus Duku Asamoah, Angelina Efia Mantey, Inemesit Okon Ben, Jonathan Jato, Mike Okweesi Aggrey, Nii Korley Kortei, Theophilus Christian Fleischer   +8 more
doaj   +1 more source

Ethynyl and Ethenyl Ferrocenyl Dyads with Acridine, Acridone, and Anthraquinone

, 2016
Ethynylferrocenyl derivatives of 2,7-acridine (1, 2), 9-N-acridone (4), and 2-anthraquinone (6) are described. (Z)-10-(2-iodo-1-ethenylferrocene)-9(10H)-acridinone (3), an intermediate in the formation of 4, N-Fc(CH2)n-acridone (5; n = 8, 11), 1-Fc ...
Elise M. McGale (3081423), Brian H. Robinson (384905), Jim Simpson (1672201)   +2 more
core   +1 more source