Results 61 to 70 of about 5,634 (238)

Anion‐π+ Type AIE‐Active Photosensitizers for Ferroptosis‐Driven Photodynamic Immunotherapy Against Hypoxic Solid Tumors

Aggregate, Volume 7, Issue 1, January 2026.
An anion‐π+ type AIE photosensitizer (TMTPA NPs) with NIR emission was successfully developed through a sulfidation strategy. With its exceptional mitochondrial targeting abilities and efficient Type I ROS generation, TMTPA NPs effectively trigger ferroptosis.
Lingxiu Liu, Jianye Gong, Xue Wang, Ying Zhang, Guoyu Jiang, Jianguo Wang, Ben Zhong Tang   +6 more
wiley   +1 more source

Redetermination and absolute configuration of atalaphylline

Acta Crystallographica Section E, 2010
The title acridone alkaloid [systematic name: 1,3,5-trihydroxy-2,4-bis(3-methylbut-2-enyl)acridin-9(10H)-one], C23H25NO4, has previously been reported as crystallizing in the chiral orthorhombic space group P212121 [Chantrapromma et al. (2010).
Hoong-Kun Fun, Chin Sing Yeap, Suchada Chantrapromma   +2 more
doaj   +1 more source

Prolongation of AV nodal refractoriness by Ruta graveolens in isolated rat hearts [PDF]

, 2008
Objectives: To evaluate concentration-dependent effects of total extract of Rusta graveolens and its purified alkaloid fraction on the nodal basic and functional properties.
Golalipour, M.J., Khori, V., Marjani, A., Nayebpour, M., Semnani, S.   +4 more
core  

A Ratiometric Fluorescent Bioprobe Based on Carbon Dots and Acridone Derivate for Signal Amplification Detection Exosomal microRNA.

Analytical Chemistry, 2018
Recently, sensitive and selective detection of exosomal microRNAs (miRNAs) has been garnering significant attention, because it is related to many complex diseases, including cancer.
Yaokun Xia, Liangliang Wang, Juan Li, Xiangqi Chen, Jianming Lan, An Yan, Yun Lei, Sheng Yang, Huanghao Yang, Jinghua Chen   +9 more
semanticscholar   +1 more source

Degrees of Sulfonation: Mapping the Reactivity Landscape of Acridine and Acridone

Organics
Although sulfonated acridines and acridones are valuable scaffolds in diagnostics and materials science, to our best knowledge, there is no comprehensive study that addresses how the degree of sulfonation depends on reaction parameters. To fill this gap,
Péter Kisfaludi, Sára Spátay, Péter Huszthy, Ádám Golcs   +3 more
doaj   +1 more source

A facile synthesis of N-H-and N-substituted acridine-1,8-diones under sonic condition [PDF]

, 2013
Synthesis of an assembly of structurally important N-H- and N-substituted acridine-1,8-diones by CAN (ceric ammonium nitrate) catalysed one-pot four-component reaction of electron-deficient and electron-rich aromatic aldehydes and aromatic amines or ...
Pasha, M.A., Sudha, S.
core   +3 more sources

Fluorescent Dyes for Probing Intracellular and Subcellular Polarity

Chemistry–Methods, Volume 6, Issue 1, January 2026.
Fluorescent probes are crucial tools for measuring cellular microenvironment polarity, a parameter that influences physiological organelle function and diseases such as cancer. This text details the probes' physicochemical principles, intracellular targeting strategies, and key photophysical parameters for polarity estimation.
M. Carmen Gonzalez‐Garcia, Maria J. Ruedas‐Rama, Juan A. González‐Vera, Emilio Garcia‐Fernandez, Angel Orte   +4 more
wiley   +1 more source

Theoretical Design of Acridone-Core Energetic Materials: Assessment of Detonation Properties and Potential as Insensitive, Thermally Stable High-Energy Materials

ChemEngineering
In this study, we investigated the impact of incorporating energetic substituents such as –NO2, –NH2, –Cl, –F, N-methyl-N-nitro (CH3–N–NO2), and picryl on the detonation performance and stability of acridone-based compounds.
Jelena Tamuliene, Jonas Sarlauskas
doaj   +1 more source

Synthesis, characterization and antitumor activity of 2-methyl-9-substituted acridines [PDF]

, 2013
In the field of antitumor DNA-intercalating agents, 9-anilinoacridines play an important role due to their antiproliferative properties. Several cancer chemotherapeutics such as amascrine and nitracrine have been developed as anticancer agents.
Kumar, Rajesh, Sharma, Ankita, Sharma, Sarita, Silakari, Om, Singh, Mandeep, Kaur, Manmeet   +5 more
core   +2 more sources

Synthesis of novel cytotoxic tetracyclic acridone derivatives and study of their molecular docking, ADMET, QSAR, bioactivity and protein binding properties

Scientific Reports, 2020
Acridone based synthetic and natural products with inherent anticancer activity advancing the research and generating a large number of structurally diversified compounds.
Rajkumar Veligeti, R. Madhu, J. Anireddy, Visweswara Rao Pasupuleti, Vijaya Kumar Reddy Avula, K. Ethiraj, Srinivas Uppalanchi, S. Kasturi, Yogeeswari Perumal, H. Anantaraju, N. Polkam, Mallilkarjuna Reddy Guda, Swetha Vallela, G. Zyryanov   +13 more
semanticscholar   +1 more source