Results 51 to 60 of about 2,622 (202)

Antioxidant Chemistry of Phenolics in Chinese Herbal Medicines: A Holism‐Based Review

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Phenolic antioxidants in CHMs mainly include chalcone, stilbene, flavonoid, xanthone, and Diels–Alder‐type adducts. They undergo direct and indirect pathways to exert antioxidant action. The indirect pathway is transition metal‐chelating, while the direct pathway comprises several redox‐based reactions (e.g., SET and HAT) and RAF reactions.
Xican Li
wiley   +1 more source

A New Coumarin-Acridone Compound as a Fluorescence Probe for Fe³⁺ and Its Application in Living Cells and Zebrafish

Molecules, 2021
A new coumarin-acridone fluorescent probe S was designed and synthesized, and the structure was confirmed with 1H/13C NMR spectrometry, single-crystal X-ray diffraction, and high-resolution mass spectrometry.
Jiayong Huang, Zhenshuo Yan, Peiling Qiu, Yufeng Mo, Qizhen Cao, Qiuhong Li, Lini Huo, Lichun Zhao   +7 more
doaj   +1 more source

Degrees of Sulfonation: Mapping the Reactivity Landscape of Acridine and Acridone

Organics
Although sulfonated acridines and acridones are valuable scaffolds in diagnostics and materials science, to our best knowledge, there is no comprehensive study that addresses how the degree of sulfonation depends on reaction parameters. To fill this gap,
Péter Kisfaludi, Sára Spátay, Péter Huszthy, Ádám Golcs   +3 more
doaj   +1 more source

Coupled Excited-State Dynamics in N-Substituted 2-Methoxy-9-Acridones

Frontiers in Chemistry, 2019
Fluorophores of the acridone family have been widely employed in many applications, such as DNA sequencing, the detection of biomolecules, and the monitoring of enzymatic systems, as well as being the bases of intracellular sensors and even antitumoral ...
M. Carmen Gonzalez-Garcia, Pilar Herrero-Foncubierta, Pilar Herrero-Foncubierta, Silvia Castro, Sandra Resa, Jose M. Alvarez-Pez, Delia Miguel, Juan M. Cuerva, Emilio Garcia-Fernandez, Angel Orte   +9 more
doaj   +1 more source

Discovery of novel polysubstituted N-alkyl acridone analogues as histone deacetylase isoform-selective inhibitors for cancer therapy

Journal of Enzyme Inhibition and Medicinal Chemistry, 2023
Pan-histone deacetylase (HDAC) inhibitors often have some toxic side effects. In this study, three series of novel polysubstituted N-alkyl acridone analogous were designed and synthesised as HDAC isoform-selective inhibitors.
Ze Wang, Li Zhao, Bo Zhang, Jiahe Feng, Yule Wang, Bin Zhang, Haixiao Jin, Lijian Ding, Ning Wang, Shan He   +9 more
doaj   +1 more source

Ueber Phenylantranilsäure und Acridon [PDF]

Berichte der deutschen chemischen Gesellschaft, 1892
n ...
Graebe, C., Lagodzinski, K.
openaire   +1 more source

Assessment of DNA Topoisomerase I Unwinding Activity, Radical Scavenging Capacity, and Inhibition of Breast Cancer Cell Viability of N-alkyl-acridones and N,N′-dialkyl-9,9′-biacridylidenes

Biomolecules, 2019
The anticancer activity of acridone derivatives has attracted increasing interest, therefore, a variety of substituted analogs belonging to this family have been developed and evaluated for their anti-cancer properties.
Marios G. Krokidis, Zara Molphy, Eleni K. Efthimiadou, Marianna Kokoli, Smaragda-Maria Argyri, Irini Dousi, Annalisa Masi, Kyriakos Papadopoulos, Andrew Kellett, Chryssostomos Chatgilialoglu   +9 more
doaj   +1 more source

Ultrasound-Assisted Wittig Reaction for the Synthesis of 3-Substituted 4-Chloroquinolines and Quinolin-4(1H)-ones with Extended π-Conjugated Systems

Journal of Chemistry, 2022
3-(Vinyl-/buta-1,3-dien-1-yl/4-phenylbuta-1,3-dien-1-yl)-4-chloro quinolines and quinolin-4(1H)-ones were synthesized by ultrasound-assisted Wittig reaction of the corresponding 4-chloro-3-formylquinoline and 3-formylquinolin-4(1H)-ones with ...
Wahiba Frites, Massaab Khalfaoui, Lamouri Hammal, Vera L. M. Silva, Artur M. S. Silva   +4 more
doaj   +1 more source

Toward Sustainable Carbonylation Reactions Enabled by CO Surrogates in Green Solvents

ChemSusChem, Volume 19, Issue 13, 14 July 2026.
Carbonylation reactions offer a sustainable route to valuable carbonyl compounds. This review highlights methodologies that exploit carbonylative coupling to drastically enhance process sustainability, avoiding the direct use of CO through CO surrogates and promoting syntheses in green solvents potentially derived from renewable and sustainable sources.
Francesco Messa, Serena Perrone, Antonio Salomone   +2 more
wiley   +1 more source

Theoretical Design of Acridone-Core Energetic Materials: Assessment of Detonation Properties and Potential as Insensitive, Thermally Stable High-Energy Materials

ChemEngineering
In this study, we investigated the impact of incorporating energetic substituents such as –NO2, –NH2, –Cl, –F, N-methyl-N-nitro (CH3–N–NO2), and picryl on the detonation performance and stability of acridone-based compounds.
Jelena Tamuliene, Jonas Sarlauskas
doaj   +1 more source