Results 51 to 60 of about 5,634 (238)
Aggregate, Volume 7, Issue 4, April 2026.In a series of indolo[3,2‐b]carbazoles (X‐ICZ‐p1; X = F, Cl, Br), the afterglow properties are shaped by modulating intersystem crossing (ISC/rISC) and phosphorescence rates. F/Cl‐ICZ‐p1 systems show moderate rates, achieving color‐tunable, dual‐mode afterglow in polymethyl methacrylate from persistent thermally activated delayed fluorescence (pTADF ...
Jiang Zhao +4 more
wiley +1 more source
Biomolecules, 2019 The anticancer activity of acridone derivatives has attracted increasing interest, therefore, a variety of substituted analogs belonging to this family have been developed and evaluated for their anti-cancer properties.
Marios G. Krokidis +9 more
doaj +1 more source
A Unique Topoisomerase II Inhibitor with Dose-Affected Anticancer Mechanisms and Less Cardiotoxicity
Cells, 2021 Type II DNA topoisomerase (topo II) is an essential nuclear enzyme and a well-validated anticancer drug target. Previously, we have carried out several rounds of structural optimizations on our in-house topo II inhibitor E17, which was shown to have ...
Zhi-Ying Li, Guang-Sen Xu, Xun Li
doaj +1 more source
Improving the fluorescent probe acridonylalanine through a combination of theory and experiment [PDF]
, 2018 Acridonylalanine (Acd) is a useful fluorophore for studying proteins by fluorescence spectroscopy, but it can potentially be improved by being made longer wavelength or brighter.
Barrett, Taylor M. +12 more
core
Acridone alkaloids and flavones from the leaves of Citrus reticulata
Natural Product Research, 2021 A new acridone alkaloid, reticarcidone A (1), decorated with an oxygenated isopentenyl group between C-1 and C-2, was isolated from the leaves of Citrus reticulata Blanco, together with nine known acridone alkaloids (2–10) and fifteen flavones compounds (
Ye Ye, Gang Xu, Dong-Liang Li
semanticscholar +1 more source
Unravelling the Functional Diversity of Type III Polyketide Synthases in Fungi
Angewandte Chemie, Volume 137, Issue 44, October 27, 2025.Type III polyketide synthases (T3PKSs) produce diverse compounds of ecological and clinical importance. Here, the activity of 37 fungal T3PKSs was profiled, revealing unexpected products and generating several pharmaceutical precursors. The machine learning model trained on the activity data accurately extrapolates the predictions to other enzymes and ...
Nika Sokolova +3 more
wiley +2 more sources
Coupled Excited-State Dynamics in N-Substituted 2-Methoxy-9-Acridones
Frontiers in Chemistry, 2019 Fluorophores of the acridone family have been widely employed in many applications, such as DNA sequencing, the detection of biomolecules, and the monitoring of enzymatic systems, as well as being the bases of intracellular sensors and even antitumoral ...
M. Carmen Gonzalez-Garcia +9 more
doaj +1 more source
Temperature dependent NIR emitting lanthanide-PMO/silica hybrid materials [PDF]
, 2017 Two materials - a mesoporous silica (MS) and a periodic mesoporous organosilica (PMO) functionalized with dipyridyl-pyridazine (dppz) units were grafted with near-infrared (NIR) emitting lanthanide (Nd3+, Er3+, Yb3+) complexes in an attempt to obtain ...
Esquivel, Dolores +5 more
core +2 more sources
ACS Omega, 2021 A modular and flexible three-step synthetic strategy has been developed for the synthesis of acridone natural products of biological significance. The tetracyclic core of acridone derivatives has been achieved efficiently in high yield from commercially ...
T. Mandal +3 more
semanticscholar +1 more source
Application of Lanthanide Shift Reagent to the 1H-NMR Assignments of Acridone Alkaloids
Molecules, 2020 This study investigates the application of the paramagnetic shift reagent tris(dipivaloylmethanato)-europium(III) in NMR spectral studies of permethoxyacridone alkaloids (1–3) and pyranoacridone alkaloids (4–6).
Sio-Hong Lam +5 more
doaj +1 more source