Results 1 to 10 of about 26,998 (146)

Patient reported outcome data from acromegaly patients treated with injectable somatostatin receptor ligands (SRLs) in routine clinical practice

BMC Endocrine Disorders, 2020
Background Acromegaly patients managed on Somatostatin receptor ligands (SRLs), the most common first-line pharmacotherapy for acromegaly, may still experience acromegaly symptoms such as headache, sweating, fatigue, soft tissue swelling, and joint pain,
Eliza B. Geer, Jill Sisco, Daphne T. Adelman, William H. Ludlam, Asi Haviv, Shuqian Liu, Susan D. Mathias, Dana Gelbaum, Lizheng Shi   +8 more
doaj   +2 more sources

Insulin Resistance in Patients With Acromegaly

Frontiers in Endocrinology, 2019
Acromegaly is characterized by chronic overproduction of growth hormone (GH) that leads to insulin resistance, glucose intolerance and, ultimately, diabetes. The GH-induced sustained stimulation of lipolysis plays a major role not only in the development
Greisa Vila, Jens Otto L. Jørgensen, Anton Luger, Günter K. Stalla   +3 more
doaj   +2 more sources

Consensus on criteria for acromegaly diagnosis and remission

Pituitary, 2023
Purpose The 14th Acromegaly Consensus Conference was convened to consider biochemical criteria for acromegaly diagnosis and evaluation of therapeutic efficacy. Methods Fifty-six acromegaly experts from 16 countries reviewed and discussed current evidence
Andrea Giustina, N. Biermasz, F. Casanueva, Maria Fleseriu, Pietro Mortini, Christian J. Strasburger, A. J. van der Lely, J. Wass, S. Melmed, Giuseppe Ariel Albert Martin Cesar Thierry Michael Philippe Banfi Barkan Beckers Bidlingmaier Boguszewski Brue, Giuseppe Banfi, A. Barkan, Albert Beckers, M. Bidlingmaier, C. L. Boguszewski, T. Brue, M. Buchfelder, Philippe Chanson, S. Chiloiro, Annamaria Colao, Eva C. Coopmans, Daniela Esposito, D. Ferone, S. Frara, M. Gadelha, E. Geer, E. Ghigo, Y. Greenman, M. Gurnell, Ken K. Y. Ho, A. Ioachimescu, G. Johannsson, Jens Otto Lunde Jørgensen, U. B. Kaiser, N. Karavitaki, L. Katznelson, S. Lamberts, M. Losa, A. Luger, R. Luque, P. Maffei, Mónica Marazuela, S. Neggers, Alberto M. Pereira, L. Persani, S. Petersenn, Martin Reincke, Roberto Salvatori, Susan N. Samson, Katharina Schilbach, Ilan Shimon, S. Tsagarakis, M. Zatelli   +52 more
semanticscholar   +1 more source

Old Wine in a New Bottle: Acromegaly Presenting as Diabetic Ketoacidosis [PDF]

Journal of Clinical and Diagnostic Research, 2021
Acromegaly is a rare disease characterised by chronic excess of Growth Hormone (GH) levels. Insulin signalling is impaired, gluconeogenesis is excess and peripheral insulin resistance is increased in acromegaly causing hyperglycaemia and diabetes ...
Sowrabha Bhat, Subhodip Pramanik, Pradip Mukhopadhyay, Subhankar Chowdhury   +3 more
doaj   +1 more source

Association of Epicardial Adipose Tissue Thickness with Cardiovascular Risk in Acromegaly

Medeniyet Medical Journal, 2022
Objective: Acromegaly is a rare disease associated with increased mortality. Reports on coronary artery disease in acromegaly are controversial. This study aimed to investigate the possible association of epicardial adipose tissue thickness with ...
Bulent CAN, Fatma OLCAY COSKUN, Sercin OZKOK, Mumtaz TAKIR   +3 more
doaj   +1 more source

Multiomics Approach to Acromegaly: Unveiling Translational Insights for Precision Medicine [PDF]

Endocrinology and Metabolism, 2023
The clinical characteristics and prognoses of acromegaly vary among patients. Assessment of current and novel predictors can lead to multilevel categorization of patients, allowing integration into new clinical guidelines and a reduction in the increased
Kyungwon Kim, Cheol Ryong Ku, Eun Jig Lee   +2 more
doaj   +1 more source

Prevalence and risk factors of sleep breathing disorders in patients with acromegaly from Moscow region [PDF]

Терапевтический архив, 2018
Aim. Assessment of prevalence and risk factors of sleep breathing disorders in patients with acromegaly from Moscow region. Materials and methods. Cardiorespiratory monitoring was executed to 55 patients with acromegaly (18 men and 37 women): 27 patients
Yu A Kovaleva, A V Dreval, N V Kulakov, S I Fedorova, I A Ilovayskaya   +4 more
doaj   +1 more source

Ageing genetic signature of hypersomatotropism

Open Biology, 2021
Acromegaly is a pathological condition that is caused by over-secretion of growth hormone (GH) and develops primarily from a pituitary adenoma. Excess GH exposure over a prolonged period of time leads to a wide range of systemic manifestations and ...
Abdalla Elbialy
doaj   +1 more source

The acromegaly lipodystrophy

Frontiers in Endocrinology, 2022
Growth hormone (GH) and insulin-like growth factor 1 (IGF-1) are essential to normal growth, metabolism, and body composition, but in acromegaly, excesses of these hormones strikingly alter them.
Pamela U. Freda
doaj   +1 more source

Increased Risk of Hip Fracture in Patients with Acromegaly: A Nationwide Cohort Study in Korea [PDF]

Endocrinology and Metabolism, 2023
Background Acromegaly leads to various skeletal complications, and fragility fractures are emerging as a new concern in patients with acromegaly. Therefore, this study investigated the risk of fractures in Korean patients with acromegaly. Methods We used
Jiwon Kim, Namki Hong, Jimi Choi, Ju Hyung Moon, Eui Hyun Kim, Eun Jig Lee, Sin Gon Kim, Cheol Ryong Ku   +7 more
doaj   +1 more source