Results 1 to 10 of about 38,061 (254)

Patient reported outcome data from acromegaly patients treated with injectable somatostatin receptor ligands (SRLs) in routine clinical practice

open access: yesBMC Endocrine Disorders, 2020
Background Acromegaly patients managed on Somatostatin receptor ligands (SRLs), the most common first-line pharmacotherapy for acromegaly, may still experience acromegaly symptoms such as headache, sweating, fatigue, soft tissue swelling, and joint pain,
Eliza B. Geer   +8 more
doaj   +2 more sources

The acromegaly lipodystrophy

open access: yesFrontiers in Endocrinology, 2022
Growth hormone (GH) and insulin-like growth factor 1 (IGF-1) are essential to normal growth, metabolism, and body composition, but in acromegaly, excesses of these hormones strikingly alter them.
Pamela U. Freda
doaj   +3 more sources

Insulin Resistance in Patients With Acromegaly

open access: yesFrontiers in Endocrinology, 2019
Acromegaly is characterized by chronic overproduction of growth hormone (GH) that leads to insulin resistance, glucose intolerance and, ultimately, diabetes. The GH-induced sustained stimulation of lipolysis plays a major role not only in the development
Greisa Vila   +3 more
doaj   +2 more sources

Incidence of bronchiectasis in patients with acromegaly: a cohort study. [PDF]

open access: yesFront Endocrinol (Lausanne)
ObjectiveAssociations between acromegaly and several respiratory diseases, such as obstructive lung disease or sleep apnea, have been suggested, but the relationship between bronchiectasis and acromegaly is unclear.
Gil HI, Han K, Hong S, Park CY.
europepmc   +2 more sources

Knowledge and attitudes of primary care physicians regarding acromegaly: a survey study with multinational participation. [PDF]

open access: yesBMC Prim Care
Background Acromegaly is a disease with high morbidity and mortality rates. The role of primary care physicians is very important in the early diagnosis of acromegaly.
Fenercioglu AK   +6 more
europepmc   +2 more sources

Old Wine in a New Bottle: Acromegaly Presenting as Diabetic Ketoacidosis [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2021
Acromegaly is a rare disease characterised by chronic excess of Growth Hormone (GH) levels. Insulin signalling is impaired, gluconeogenesis is excess and peripheral insulin resistance is increased in acromegaly causing hyperglycaemia and diabetes ...
Sowrabha Bhat   +3 more
doaj   +1 more source

Increased Risk of Hip Fracture in Patients with Acromegaly: A Nationwide Cohort Study in Korea [PDF]

open access: yesEndocrinology and Metabolism, 2023
Background Acromegaly leads to various skeletal complications, and fragility fractures are emerging as a new concern in patients with acromegaly. Therefore, this study investigated the risk of fractures in Korean patients with acromegaly. Methods We used
Jiwon Kim   +7 more
doaj   +1 more source

Prevalence and risk factors of sleep breathing disorders in patients with acromegaly from Moscow region [PDF]

open access: yesТерапевтический архив, 2018
Aim. Assessment of prevalence and risk factors of sleep breathing disorders in patients with acromegaly from Moscow region. Materials and methods. Cardiorespiratory monitoring was executed to 55 patients with acromegaly (18 men and 37 women): 27 patients
Yu A Kovaleva   +4 more
doaj   +1 more source

Ageing genetic signature of hypersomatotropism

open access: yesOpen Biology, 2021
Acromegaly is a pathological condition that is caused by over-secretion of growth hormone (GH) and develops primarily from a pituitary adenoma. Excess GH exposure over a prolonged period of time leads to a wide range of systemic manifestations and ...
Abdalla Elbialy
doaj   +1 more source

Acromegaly: Clinical Care in Central and Eastern Europe, Israel, and Kazakhstan

open access: yesFrontiers in Endocrinology, 2022
Acromegaly is a rare condition typically caused by benign pituitary adenomas, resulting in excessive production of growth hormone. Clinical manifestations of acromegaly are diverse, varying from the overgrowth of body tissue to cardiovascular, metabolic,
Marek Bolanowski   +17 more
doaj   +1 more source

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