Results 1 to 10 of about 23,672 (222)

Real-world burden of disease, treatment, and healthcare resource utilization in acromegaly: a quantitative survey of patient experiences [PDF]

Journal of Patient-Reported Outcomes
Background Acromegaly is a rare endocrine disease caused by excessive growth hormone (GH) secretion typically due to a pituitary adenoma. Patients ineligible for or with an inadequate response to surgery and/or radiotherapy often require pharmacotherapy ...
Maxwell Koobatian, Jill Sisco, Janetricks C. Okeyo, Alan Krasner, Tiffany P. Quock   +4 more
doaj   +2 more sources

Healthcare utilization and costs among patients with acromegaly in the United States [PDF]

Journal of Comparative Effectiveness Research
Aim: Recent evidence regarding the healthcare resource utilization (HCRU) and associated costs of acromegaly is limited. Materials & methods: This retrospective, cross-sectional administrative claims analysis (IQVIA Pharmetrics Plus) identified ...
Tiffany P Quock, Eunice Chang, Ashis K Das, Amanda Speller, Marian H Tarbox, Melinda L Rossi, Stacy K Rattana, Ingrid E Paulson, Michael S Broder   +8 more
doaj   +2 more sources

Clinical and economic burden among older adults with acromegaly in the United States [PDF]

Journal of Comparative Effectiveness Research
Aim: To compare healthcare resource utilization (HCRU) and costs between older adults with and without acromegaly. Materials & methods: Using 2017–2022 100% Medicare Research Identifiable Files, we identified beneficiaries (≥65 years) with prevalent ...
Tiffany P Quock, Eunice Chang, Ashis K Das, Amanda Speller, Marian H Tarbox, Stacy K Rattana, Ingrid E Paulson, Michael S Broder   +7 more
doaj   +2 more sources

Association of Epicardial Adipose Tissue Thickness with Cardiovascular Risk in Acromegaly

Medeniyet Medical Journal, 2022
Objective: Acromegaly is a rare disease associated with increased mortality. Reports on coronary artery disease in acromegaly are controversial. This study aimed to investigate the possible association of epicardial adipose tissue thickness with ...
Bulent CAN, Fatma OLCAY COSKUN, Sercin OZKOK, Mumtaz TAKIR   +3 more
doaj   +1 more source

Multiomics Approach to Acromegaly: Unveiling Translational Insights for Precision Medicine [PDF]

Endocrinology and Metabolism, 2023
The clinical characteristics and prognoses of acromegaly vary among patients. Assessment of current and novel predictors can lead to multilevel categorization of patients, allowing integration into new clinical guidelines and a reduction in the increased
Kyungwon Kim, Cheol Ryong Ku, Eun Jig Lee   +2 more
doaj   +1 more source

The acromegaly lipodystrophy

Frontiers in Endocrinology, 2022
Growth hormone (GH) and insulin-like growth factor 1 (IGF-1) are essential to normal growth, metabolism, and body composition, but in acromegaly, excesses of these hormones strikingly alter them.
Pamela U. Freda
doaj   +1 more source

Old Wine in a New Bottle: Acromegaly Presenting as Diabetic Ketoacidosis [PDF]

Journal of Clinical and Diagnostic Research, 2021
Acromegaly is a rare disease characterised by chronic excess of Growth Hormone (GH) levels. Insulin signalling is impaired, gluconeogenesis is excess and peripheral insulin resistance is increased in acromegaly causing hyperglycaemia and diabetes ...
Sowrabha Bhat, Subhodip Pramanik, Pradip Mukhopadhyay, Subhankar Chowdhury   +3 more
doaj   +1 more source

Prevalence and risk factors of sleep breathing disorders in patients with acromegaly from Moscow region [PDF]

Терапевтический архив, 2018
Aim. Assessment of prevalence and risk factors of sleep breathing disorders in patients with acromegaly from Moscow region. Materials and methods. Cardiorespiratory monitoring was executed to 55 patients with acromegaly (18 men and 37 women): 27 patients
Yu A Kovaleva, A V Dreval, N V Kulakov, S I Fedorova, I A Ilovayskaya   +4 more
doaj   +1 more source

Ageing genetic signature of hypersomatotropism

Open Biology, 2021
Acromegaly is a pathological condition that is caused by over-secretion of growth hormone (GH) and develops primarily from a pituitary adenoma. Excess GH exposure over a prolonged period of time leads to a wide range of systemic manifestations and ...
Abdalla Elbialy
doaj   +1 more source

Presence of cerebral microbleeds is associated with cognitive decline in acromegaly

Frontiers in Oncology, 2022
BackgroundCognitive decline in acromegaly has gained increasing attention. Cerebral microbleeds (CMBs) as radiographic markers for microvascular injury have been linked to various types of cognitive decline. However, the association between CMB formation
Zhengxing Xie, Zhengxing Xie, Zhengxing Xie, Yan Zhuang, Yan Zhuang, Zongqiang Zhang, Jieping Liu, Jieping Liu   +7 more
doaj   +1 more source