Results 1 to 10 of about 30,948 (147)
Prevalence of acromegaly in patients with symptoms of sleep apnea. [PDF]
PLoS ONE, 2017 Acromegaly is a rare disease with nonspecific symptoms with acral enlargement being almost universally present at diagnosis. The estimated prevalence is 40-125 cases/million but targeted universal screening studies have found a higher prevalence (about ...
Gemma Sesmilo +14 more
doaj +5 more sources
Association of Epicardial Adipose Tissue Thickness with Cardiovascular Risk in Acromegaly
Medeniyet Medical Journal, 2022 Objective: Acromegaly is a rare disease associated with increased mortality. Reports on coronary artery disease in acromegaly are controversial. This study aimed to investigate the possible association of epicardial adipose tissue thickness with ...
Bulent CAN +3 more
doaj +1 more source
Multiomics Approach to Acromegaly: Unveiling Translational Insights for Precision Medicine [PDF]
Endocrinology and Metabolism, 2023 The clinical characteristics and prognoses of acromegaly vary among patients. Assessment of current and novel predictors can lead to multilevel categorization of patients, allowing integration into new clinical guidelines and a reduction in the increased
Kyungwon Kim +2 more
doaj +1 more source
Old Wine in a New Bottle: Acromegaly Presenting as Diabetic Ketoacidosis [PDF]
Journal of Clinical and Diagnostic Research, 2021 Acromegaly is a rare disease characterised by chronic excess of Growth Hormone (GH) levels. Insulin signalling is impaired, gluconeogenesis is excess and peripheral insulin resistance is increased in acromegaly causing hyperglycaemia and diabetes ...
Sowrabha Bhat +3 more
doaj +1 more source
Frontiers in Endocrinology, 2022 Growth hormone (GH) and insulin-like growth factor 1 (IGF-1) are essential to normal growth, metabolism, and body composition, but in acromegaly, excesses of these hormones strikingly alter them.
Pamela U. Freda
doaj +1 more source
Prevalence and risk factors of sleep breathing disorders in patients with acromegaly from Moscow region [PDF]
Терапевтический архив, 2018 Aim. Assessment of prevalence and risk factors of sleep breathing disorders in patients with acromegaly from Moscow region. Materials and methods. Cardiorespiratory monitoring was executed to 55 patients with acromegaly (18 men and 37 women): 27 patients
Yu A Kovaleva +4 more
doaj +1 more source
Ageing genetic signature of hypersomatotropism
Open Biology, 2021 Acromegaly is a pathological condition that is caused by over-secretion of growth hormone (GH) and develops primarily from a pituitary adenoma. Excess GH exposure over a prolonged period of time leads to a wide range of systemic manifestations and ...
Abdalla Elbialy
doaj +1 more source
Gene Expression Signature in Adipose Tissue of Acromegaly Patients. [PDF]
, 2014 To study the effect of chronic excess growth hormone on adipose tissue, we performed RNA sequencing in adipose tissue biopsies from patients with acromegaly (n = 7) or non-functioning pituitary adenomas (n = 11).
Barkan, Ariel L +5 more
core +12 more sources
Increased Risk of Hip Fracture in Patients with Acromegaly: A Nationwide Cohort Study in Korea [PDF]
Endocrinology and Metabolism, 2023 Background Acromegaly leads to various skeletal complications, and fragility fractures are emerging as a new concern in patients with acromegaly. Therefore, this study investigated the risk of fractures in Korean patients with acromegaly. Methods We used
Jiwon Kim +7 more
doaj +1 more source
Acromegaly: Clinical Care in Central and Eastern Europe, Israel, and Kazakhstan
Frontiers in Endocrinology, 2022 Acromegaly is a rare condition typically caused by benign pituitary adenomas, resulting in excessive production of growth hormone. Clinical manifestations of acromegaly are diverse, varying from the overgrowth of body tissue to cardiovascular, metabolic,
Marek Bolanowski +17 more
doaj +1 more source