Results 91 to 100 of about 57,421 (320)

Acromegaly at diagnosis in 3173 patients from the Liège Acromegaly Survey (LAS) Database

Endocrine-Related Cancer, 2017
Acromegaly is a rare disorder caused by chronic growth hormone (GH) hypersecretion. While diagnostic and therapeutic methods have advanced, little information exists on trends in acromegaly characteristics over time.
P. Pétrossians, A. Daly, E. Natchev, L. Maione, K. Blijdorp, M. Sahnoun-Fathallah, R. Auriemma, A. Diallo, A. Hulting, D. Ferone, V. Hána, S. Filipponi, C. Sievers, C. Nogueira, C. Fajardo-Montañana, D. Carvalho, G. Stalla, M. Jaffrain-Rea, B. Delemer, A. Colao, T. Brue, S. Neggers, S. Zacharieva, P. Chanson, A. Beckers   +24 more
semanticscholar   +1 more source

Clinical MEN-1 Among a Large Cohort of Patients With Acromegaly

Journal of Clinical Endocrinology and Metabolism, 2020
Context Clinical multiple endocrine neoplasia type 1 (MEN-1) is diagnosed by the presence of at least 2 MEN-1–associated tumors. Many patients with acromegaly and clinical MEN-1 yield negative testing for MEN1 mutations.
L. Nachtigall, F. Guarda, K. Lines, Alireza Ghajar, L. Dichtel, Giselle Mumbach, Wenxiu Zhao, Xun Zhang, N. Tritos, B. Swearingen, K. Miller, R. Thakker   +11 more
semanticscholar   +1 more source

Acromegaly [PDF]

Trends in Endocrinology & Metabolism, 1992
In the majority of cases, acromegaly is due to GH hypersecretion by a somatotroph pituitary tumor. The etiology of acromegaly is not known, and may be related to GHRH hypersecretion, intrinsic pituitary defect, or a combination thereof. Recent physiologic data and molecular biology techniques provide insights into the pathophysiology of this condition.
openaire   +3 more sources

Hypertension and Acromegaly [PDF]

Endocrinology and Metabolism Clinics of North America, 2019
Hypertension is one of the most frequent complications in acromegaly, with a median frequency of 33.6% (range, 11%-54.7%). Although the pathogenesis has not been fully elucidated, it probably results from concomitant factors leading to expansion of extracellular fluid volume, increase of peripheral vascular resistance, and development of sleep apnea ...
Puglisi S, Terzolo M
openaire   +4 more sources

Hyperhidrosis: don't sweat it

Internal Medicine Journal, EarlyView.
Abstract Hyperhidrosis is an under‐reported and under‐treated condition that causes significant patient morbidity. Secondary causes require consideration, but the vast majority of cases are idiopathic. The condition is encountered by a range of clinicians, including neurologists, dermatologists and endocrinologists, and it pays to be familiar with the ...
Mitchell J. Lycett, Karl Ng
wiley   +1 more source

Fragility fractures in well‐differentiated gastroenteropancreatic neuroendocrine tumors: Results from a multicentered retrospective study

Journal of Neuroendocrinology, EarlyView.
Abstract Patients with gastroenteropancreatic–neuroendocrine tumors (GEP‐NETs) may present skeletal fragility that might be related to multiple factors, including bone metastases, vitamin D deficiency, hormone secretion, and disease treatments. This study examines the prevalence and determinants of fragility fractures in low grading (G1‐G2) GEP‐NETs ...
Alessandro Brunetti, Miriam Cellini, Elisabetta Lavezzi, Alessandro Zerbi, Giuseppe Ferrillo, Maria Francesca Birtolo, Alfredo Berruti, Guido Cavati, Marta Lagana, Luigi Gennari, Rossano Girometti, Chiara Zuiani, Franco Grimaldi, Andrea G. Lania, Fabio Vescini, Gherardo Mazziotti   +15 more
wiley   +1 more source

Clinical and biochemical characteristics of patients with acromegaly and normal or increased prolactin levels

Alʹmanah Kliničeskoj Mediciny
Background: Prevalence of hyperprolactinemia in patients with acromegaly is 30 to 40%. Since recently, the necessity of screening for acromegaly in hyperprolactinemic patients with pituitary adenoma has been actively debated. The literature on this issue
Yuliya A. Kukushkina, Irena A. Ilovayskaya   +1 more
doaj   +1 more source

Hyperglycemia induced by pasireotide in patients with Cushing’s disease or acromegaly [PDF]

, 2016
PURPOSE: Cushing’s disease (CD) and acromegaly are characterized by excessive hormone secretion resulting in comorbidities such as impaired glucose metabolism, diabetes and hypertension.
Silverstein, Julie M
core   +2 more sources

The 20 kDa isoform of the human growth hormone variant alters adipose and muscle gene expression differently than human growth hormone

Journal of Neuroendocrinology, EarlyView.
Abstract The 20 kDa isoform of human growth hormone variant (20K hGH‐V) (derived from the GH2 gene) has previously been shown to promote growth but lacks the diabetogenic and lactogenic activities of human GH (derived from the GH1 gene). That is, 20K hGH‐V‐treated mice have similar body size and composition to hGH‐treated mice, as well as improved ...
Jonathan A. Young, Jolie Bogart, Mat Buchman, Silvana Duran‐Ortiz, Stephen Bell, John J. Kopchick, Darlene E. Berryman, Edward O. List   +7 more
wiley   +1 more source

Acromegaly in pregnancy

Indian Journal of Endocrinology and Metabolism, 2012
Pregnancy in a patient with acromegaly is a rare occurrence. Here in, we report a patient with acromegaly who presented to us in the 2(nd) trimester of pregnancy with visual loss in the right eye. Her vision improved after surgery. She went on to have an uneventful pregnancy and delivered a term baby, by caesarian section.
Jiji Elizabeth Mathews, Vedantam Rajshekhar, Simon Rajaratnam, T George Koshy   +3 more
openaire   +3 more sources