Expression of microRNA related to bone remodeling regulation in plasma in patients with acromegaly
Ожирение и метаболизм, 2017 Backgraund. MiсroRNA are small regulatory factors that regulate gene expression by post-transcriptional regulation of mRNA, playing an important role in numerous cellular processes including organogenesis, apoptosis, cell proliferation and ...
Tatiana A. Grebennikova +6 more
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Effects of human recombinant growth hormone on exercise capacity, cardiac structure, and cardiac function in patients with adult-onset growth hormone deficiency [PDF]
, 2017 Objective Epidemiological studies suggest that adult-onset growth hormone deficiency (AGHD) might increase the risk of death from cardiovascular causes. Methods This was a 6-month double-blind, placebo-controlled, randomised, cross-over trial followed by
Atkin, S. L. +11 more
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Leptin Level in Newly Diagnosed Iraqi Acromegaly Patients
Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2018 Acromegaly is a serious endocrine disease resulting from an increase of growth hormone in the blood. Excessive growth hormone secretion may be caused by an adenoma of the pituitary.
Noor Thair Tahir
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SAT-267 Pregnancy in Acromegaly: Report of Five Cases [PDF]
, 2020 Iulia Florentina Burcea +5 more
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The decrease in growth hormone (GH) response after repeated stimulation with GH-Releasing hormone is partly caused by an elevation of somatostatin tonus. [PDF]
, 1996 Repeated injection of GHRH leads to a decrease in the GH response in normal subjects. Arginine (Arg) stimulates GH secretion by suppression of hypothalamic somatostatin.
Mehltretter, Gerhard +5 more
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Sclerostin levels in patients with acromegaly
Endokrynologia PolskaAcromegaly is a rare, endocrine condition characterized by autonomous excessive secretion of growth hormone, causing numerous complications, including impairment of bone microarchitecture.
Arnika Wydra +4 more
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Obstructive Sleep Apnea Syndrome in Acromegaly Before and After Treatment
Türk Uyku Tıbbı Dergisi, 2014 Introduction Obstructive sleep apnea syndrome (OSAS) prevalence in acromegaly patients is very common compared with general population. It is thought that OSAS in acromegaly patients evolve because of reversible and irreversible anatomical changes ...
Selda Korkmaz +5 more
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Fractures in pituitary adenoma patients from the Dutch National Registry of Growth Hormone Treatment in Adults [PDF]
, 2016 Purpose: The effects of growth hormone (GH) replacement therapy on fracture risk in adult GH deficient (GHD) patients with different etiologies of pituitary GHD are not well known, due to limited data.
Bunderen, C.C. (Christa) van +5 more
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AIP and MEN1 mutations and AIP immunohistochemistry in pituitary adenomas in a tertiary referral center. [PDF]
, 2019 Background: Pituitary adenomas have a high disease burden due to tumor growth/ invasion and disordered hormonal secretion. Germline mutations in genes such as MEN1 and AIP are associated with early onset of aggressive pituitary adenomas that can be ...
Cano González, David A. +2 more
core
Uso de lanreotida en combinación con cabergolina o pegvisomant en la práctica clínica en pacientes con acromegalia: el estudio ACROCOMB [PDF]
, 2016 [Abstract] PURPOSE: To describe real-world use of lanreotide combination therapy for acromegaly. PATIENTS AND METHODS: ACROCOMB is a retrospective observational Spanish study of patients with active acromegaly treated with lanreotide combination therapy
Bernabéu, Ignacio +18 more
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