Results 11 to 20 of about 24,245 (182)

Static and Dynamic Balance Is Impaired in Patients With Long-Term, Well-Controlled Acromegaly: A Cross-Sectional Study. [PDF]

Clin Endocrinol (Oxf)
ABSTRACT Objective Balance impairment is an underrecognized complication of acromegaly with potentially serious consequences for affected patients. In this study, we aimed to assess the balance in patients with long‐term acromegaly compared to non‐acromegalic controls. Design Cross‐sectional study.
Rosendal C, Kvist AV, Hirata RP, Vestergaard P, Dal J.   +4 more
europepmc   +2 more sources

Acromegaly: Clinical Care in Central and Eastern Europe, Israel, and Kazakhstan

Frontiers in Endocrinology, 2022
Acromegaly is a rare condition typically caused by benign pituitary adenomas, resulting in excessive production of growth hormone. Clinical manifestations of acromegaly are diverse, varying from the overgrowth of body tissue to cardiovascular, metabolic,
Marek Bolanowski, Zaina Adnan, Mirjana Doknic, Mykola Guk, Václav Hána, Irena Ilovayskaya, Darko Kastelan, Tomaz Kocjan, Tomaz Kocjan, Martin Kužma, Akmaral Nurbekova, Catalina Poiana, Nikolette Szücs, Silvia Vandeva, Roy Gomez, Sorin Paidac, Damien Simoneau, Ilan Shimon   +17 more
doaj   +1 more source

Presence of cerebral microbleeds is associated with cognitive decline in acromegaly

Frontiers in Oncology, 2022
BackgroundCognitive decline in acromegaly has gained increasing attention. Cerebral microbleeds (CMBs) as radiographic markers for microvascular injury have been linked to various types of cognitive decline. However, the association between CMB formation
Zhengxing Xie, Zhengxing Xie, Zhengxing Xie, Yan Zhuang, Yan Zhuang, Zongqiang Zhang, Jieping Liu, Jieping Liu   +7 more
doaj   +1 more source

Is H19 RNA a Useful Marker of Acromegaly and Its Complications? A Preliminary Study

Biomedicines, 2023
Acromegaly is a rare endocrine disorder caused by somatotroph pituitary adenoma. Besides its typical symptoms, it contributes to the development of cardiovascular, metabolic, and bone comorbidities. H19 RNA is a long non-coding RNA and it is suspected to
Małgorzata Rolla, Aleksandra Jawiarczyk-Przybyłowska, Katarzyna Kolačkov, Agnieszka Zembska, Marek Bolanowski   +4 more
doaj   +1 more source

Patient reported outcome data from acromegaly patients treated with injectable somatostatin receptor ligands (SRLs) in routine clinical practice

BMC Endocrine Disorders, 2020
Background Acromegaly patients managed on Somatostatin receptor ligands (SRLs), the most common first-line pharmacotherapy for acromegaly, may still experience acromegaly symptoms such as headache, sweating, fatigue, soft tissue swelling, and joint pain,
Eliza B. Geer, Jill Sisco, Daphne T. Adelman, William H. Ludlam, Asi Haviv, Shuqian Liu, Susan D. Mathias, Dana Gelbaum, Lizheng Shi   +8 more
doaj   +1 more source

Increased Risk of Hip Fracture in Patients with Acromegaly: A Nationwide Cohort Study in Korea [PDF]

Endocrinology and Metabolism, 2023
Background Acromegaly leads to various skeletal complications, and fragility fractures are emerging as a new concern in patients with acromegaly. Therefore, this study investigated the risk of fractures in Korean patients with acromegaly. Methods We used
Jiwon Kim, Namki Hong, Jimi Choi, Ju Hyung Moon, Eui Hyun Kim, Eun Jig Lee, Sin Gon Kim, Cheol Ryong Ku   +7 more
doaj   +1 more source

Metabolic Factors Related to Interpersonal Dysfunction in Acromegaly: A Nationwide Cross-Sectional Study in China. [PDF]

CNS Neurosci Ther
Metabolic and physical factors—specifically frontal bossing, cardiovascular comorbidities, and elevated preoperative GH levels—are independent predictors of severe interpersonal dysfunction in Chinese patients with acromegaly. These findings underscore the need for integrating systematic psychosocial screening into routine neuroendocrine management to ...
Tagilapalli SK, Wang Z, Lu YL, Zhang G, Su W, Wu Z, Wang J, Rao Q, Wang H, He D, Mou Y, Yao S, Tie Y, Chen W.   +13 more
europepmc   +2 more sources

Insulin Like Growth Factor Binding Protein 7 as a Novel Diagnostic Marker in Sera of Iraqi Patients with Acromegaly

مجلة بغداد للعلوم, 2023
The purpose of this study was to measure serum levels of insulin-like growth factor-binding protein (IGFBP7), Insulin-like Growth Factor 1 (IGF-1), Growth Hormone (GH), Interleukin 6 (IL-6) and insulin in acromegaly patients and healthy controls.
Layla Othman Farhan, Baydaa Ahmed Abed, Kashtl Ghasaq J., Isam Noori Salman   +3 more
doaj   +1 more source

Tumor-infiltrating immune cells predict the response to somatostatin receptor ligands only in somatotropinomas naïve to medical therapy. [PDF]

J Neuroendocrinol
Abstract Tumor‐infiltrating immune cells (TICs) are important components of the tumor microenvironment (TME). They regulate somatotroph adenoma treatment responses to therapy with somatostatin receptor ligands (SRLs), mediated by soluble factors and cytokines. In this study, we assessed the effect of SRLs treatment on TICs.
Chiloiro S, Vicari A, Giampietro A, Mattogno PP, Cappoli N, Konini G, Calandrelli R, Lauretti L, Gaudino S, Rigante M, Rindi G, Olivi A, De Marinis L, Bianchi A, Doglietto F, Gessi M, Pontecorvi A.   +16 more
europepmc   +2 more sources

CONDITION OF THE MUSCULOSKELETAL SYSTEM IN PATIENTSWITH ACROMEGALY.

Остеопороз и остеопатии, 2010
Despite the relatively low incidence of acromegaly (60-70 cases per I million inhabitants), this disease has a special place among the heterogeneous group of diseases that lead to the defeat of the locomotor apparatus.
A S Fedotova, N N Molitvoslovova, L I Alekseeva, L Ya Rozhinskaya, A. S. Fedotova, N. N. Molitvoslovova, L. I. Alexeeva, L. Y. Rozhinskaya   +7 more
doaj   +1 more source