Real-world burden of disease, treatment, and healthcare resource utilization in acromegaly: a quantitative survey of patient experiences. [PDF]
J Patient Rep OutcomesBackground Acromegaly is a rare endocrine disease caused by excessive growth hormone (GH) secretion typically due to a pituitary adenoma. Patients ineligible for or with an inadequate response to surgery and/or radiotherapy often require pharmacotherapy ...
Koobatian M +4 more
europepmc +2 more sources
Association of Epicardial Adipose Tissue Thickness with Cardiovascular Risk in Acromegaly
Medeniyet Medical Journal, 2022 Objective: Acromegaly is a rare disease associated with increased mortality. Reports on coronary artery disease in acromegaly are controversial. This study aimed to investigate the possible association of epicardial adipose tissue thickness with ...
Bulent CAN +3 more
doaj +1 more source
Multiomics Approach to Acromegaly: Unveiling Translational Insights for Precision Medicine [PDF]
Endocrinology and Metabolism, 2023 The clinical characteristics and prognoses of acromegaly vary among patients. Assessment of current and novel predictors can lead to multilevel categorization of patients, allowing integration into new clinical guidelines and a reduction in the increased
Kyungwon Kim +2 more
doaj +1 more source
Frontiers in Endocrinology, 2022 Growth hormone (GH) and insulin-like growth factor 1 (IGF-1) are essential to normal growth, metabolism, and body composition, but in acromegaly, excesses of these hormones strikingly alter them.
Pamela U. Freda
doaj +1 more source
Old Wine in a New Bottle: Acromegaly Presenting as Diabetic Ketoacidosis [PDF]
Journal of Clinical and Diagnostic Research, 2021 Acromegaly is a rare disease characterised by chronic excess of Growth Hormone (GH) levels. Insulin signalling is impaired, gluconeogenesis is excess and peripheral insulin resistance is increased in acromegaly causing hyperglycaemia and diabetes ...
Sowrabha Bhat +3 more
doaj +1 more source
Prevalence and risk factors of sleep breathing disorders in patients with acromegaly from Moscow region [PDF]
Терапевтический архив, 2018 Aim. Assessment of prevalence and risk factors of sleep breathing disorders in patients with acromegaly from Moscow region. Materials and methods. Cardiorespiratory monitoring was executed to 55 patients with acromegaly (18 men and 37 women): 27 patients
Yu A Kovaleva +4 more
doaj +1 more source
Acromegaly: Clinical Care in Central and Eastern Europe, Israel, and Kazakhstan
Frontiers in Endocrinology, 2022 Acromegaly is a rare condition typically caused by benign pituitary adenomas, resulting in excessive production of growth hormone. Clinical manifestations of acromegaly are diverse, varying from the overgrowth of body tissue to cardiovascular, metabolic,
Marek Bolanowski +17 more
doaj +1 more source
Ageing genetic signature of hypersomatotropism
Open Biology, 2021 Acromegaly is a pathological condition that is caused by over-secretion of growth hormone (GH) and develops primarily from a pituitary adenoma. Excess GH exposure over a prolonged period of time leads to a wide range of systemic manifestations and ...
Abdalla Elbialy
doaj +1 more source
Presence of cerebral microbleeds is associated with cognitive decline in acromegaly
Frontiers in Oncology, 2022 BackgroundCognitive decline in acromegaly has gained increasing attention. Cerebral microbleeds (CMBs) as radiographic markers for microvascular injury have been linked to various types of cognitive decline. However, the association between CMB formation
Zhengxing Xie +7 more
doaj +1 more source
Is H19 RNA a Useful Marker of Acromegaly and Its Complications? A Preliminary Study
Biomedicines, 2023 Acromegaly is a rare endocrine disorder caused by somatotroph pituitary adenoma. Besides its typical symptoms, it contributes to the development of cardiovascular, metabolic, and bone comorbidities. H19 RNA is a long non-coding RNA and it is suspected to
Małgorzata Rolla +4 more
doaj +1 more source