Results 21 to 30 of about 41,662 (214)

E-cadherin expression is associated with somatostatin analogue response in acromegaly [PDF]

, 2018
Acromegaly is a rare disease resulting from hypersecretion of growth hormone (GH) and insulin‐like growth factor 1 (IGF1) typically caused by pituitary adenomas, which is associated with increased mortality and morbidity. Somatostatin analogues (SSAs)
Cano, David A., Castaño, Justo P., Dios, Elena, Flores Martínez, Álvaro, Ibáñez Costa, Alejandro, Japón Rodríguez, Miguel Ángel, Luque, Raúl M., Madrazo Atutxa, Ainara, Soto Moreno, Alfonso Manuel, Venegas Moreno, Eva, Vázquez Borrego, Mari C.   +10 more
core   +1 more source

Rheumatic manifestations of acromegaly [PDF]

Остеопороз и остеопатии, 2020
Acromegaly is a chronic endocrine disease characterized by excessive secretion of growth hormone (GH), which, in turn, leads to increased insulin-like growth factor 1 (IGF-1) secretion by the liver.
Taras S. Panevin, Lyudmila I. Alekseeva, Galina A. Melnichenko   +2 more
doaj   +1 more source

Time spent with cats is never wasted: Lessons learned from feline acromegalic cardiomyopathy, a naturally occurring animal model of the human disease [PDF]

, 2018
BackgroundIn humans, acromegaly due to a pituitary somatotrophic adenoma is a recognized cause of increased left ventricular (LV) mass. Acromegalic cardiomyopathy is incompletely understood, and represents a major cause of morbidity and mortality.
A Colao, A Colao, A Colao, A Colao, A Colao, A Colao, A Colao, A Colao, A Mestron, A Piovesan, AC Dirtu, AM Pereira, B Posch, BJ Maron, BPP Meij, BR Bond, C Paige, C-Y Liu, CJL Little, CR Lamb, David B. Church, David J. Connolly, DJ Connolly, F Fracassi, G Jacobs, G Lombardi, G Lombardi, J Dal, J Gilbert, JA Myers, JK Sangster, JM Fletcher, JR Payne, JT Lie, Kieran Borgeat, LJ Wilkie, Lois Wilkie, M Galderisi, M Lesser, M Maxie Grant, M Nishiki, M Rosca, M-LL Jaffrain-Rea, MD Kittleson, ME Peterson, ME Peterson, NJ Pereira, Norelene Harrington, NS Moise, NS Moise, O Kershaw, OM Dekkers, P Menaut, PR Fox, PR Fox, PR Fox, PR Fox, PR Fox, R Baldelli, R Gostelow, R Pivonello, RC Weichselbaum, S Brown, S Fazio, S Fazio, S Fazio, S Fieffe, S Murarka, S Niessen, SJM Niessen, SJM Niessen, SJM Niessen, SK Liu, SK Liu, Stijn J. M. Niessen, SV Keyte, T Wagner, T. Rosol, Vincenzo Lionetti, Virginia Luis Fuentes, WL McGuffin   +80 more
core   +2 more sources

Heat Intolerance and Hyperhidrosis as the only Presenting Manifestations of Acromegaly: A Case Report [PDF]

Journal of Clinical and Diagnostic Research, 2020
Acromegaly is a state of Growth Hormone (GH) excess characterised by coarse facial features, acral enlargement, hyperhidrosis, headache, visual disturbances and visceromegaly. The most common cause of acromegaly is pituitary adenoma.
TN Kamalesh, HA VIJAYA SARATHY, NT SREEDEVI   +2 more
doaj   +1 more source

Association of Vitamin D Receptor Polymorphisms With Activity of Acromegaly, Vitamin D Status and Risk of Osteoporotic Fractures in Acromegaly Patients

Frontiers in Endocrinology, 2019
Introduction: The vitamin D receptor (VDR) gene is one of the most widely studied tumorigenesis-related genes. The primary objective of this study was assessment of possible roles of VDR gene polymorphisms in acromegaly, with regard to the activity of ...
Aleksandra Jawiarczyk-Przybyłowska, Jowita Halupczok-Żyła, Katarzyna Kolačkov, Łukasz Gojny, Agnieszka Zembska, Marek Bolanowski   +5 more
doaj   +1 more source

Acromegaly presenting with myelopathy due to ossification of posterior longitudinal ligament: a case report

BMC Musculoskeletal Disorders, 2021
Background Acromegaly is a rare disease caused by high serum levels of growth hormone (GH) and insulin-like growth factor 1 (IGF-1), often originating from a pituitary adenoma.
Daisuke Kamakura, Katsunori Fukutake, Kazumasa Nakamura, Shintaro Tsuge, Keiji Hasegawa, Naobumi Tochigi, Akihito Wada, Tetsuo Mikami, Hiroshi Takahashi   +8 more
doaj   +1 more source

Serum N-Terminal Type III Procollagen Propeptide: An Indicator of Growth Hormone Excess and Response to Treatment in Feline Hypersomatotropism [PDF]

, 2016
BACKGROUND: N‐terminal type III procollagen propeptide (PIIINP) is a biomarker of soft tissue proliferation. Hypersomatotropism (HS) is associated with soft tissue proliferation.
Church, D B, Forcada, Y, Kenny, P J, Keyte, S V, Niessen, S J M   +4 more
core   +2 more sources

Acromegaly, Mr Punch and caricature. [PDF]

, 1996
The origin of Mr Punch from the Italian Pulcinella of the Commedia dell'arte is well known but his feature, large hooked nose, protruding chin, kyphosis and sternal protrusion all in an exaggerated form also suggest the caricature of an acromegalic. This
Armstrong R, Coues W P, Cruickshank G, David Bryson, De Souze-Leite J D, Dumas P, Ferrier D, Fritsche, Gourevitch D, Grossman A, Hutchinson W, Jewesbury R C, Levine D, Lucie-Smith E, Marie P, Mark L P, Soques A, Sternberg M, Toms K, Weinberg S J, Wells C   +20 more
core   +2 more sources

Polycystic ovary syndrome preceding the diagnosis of acromegaly: a retrospective study in 97 reproductive-aged women

Reproductive Biology and Endocrinology, 2023
Background Acromegaly is a disease of growth hormone excess that results in enlargement of extremities, abnormal glucose and lipid metabolism, and gonadal disruption. Manifestations of the disease are insidious and typically lead to a diagnostic delay of
Anamil M. Khiyami, Tahereh Orouji Jokar, Hussein M. Abdallah, Paul A. Gardner, Georgios A. Zenonos, Aaron K. Styer, Pouneh K. Fazeli   +6 more
doaj   +1 more source

Excessive growth hormone expression in male GH transgenic mice adversely alters bone architecture and mechanical strength [PDF]

, 2015
Patients with acromegaly have a higher prevalence of vertebral fractures despite normal bone mineral density (BMD), suggesting that GH overexpression has adverse effects on skeletal architecture and strength. We used giant bovine GH (bGH) transgenic mice
Chavassieux, P, Chenu, C, Hopkinson, M, Javaheri, B, Kopchick, J, Korbonits, M, Lim, SV, List, E, Marenzana, M, Pereira, M, Roux, J   +10 more
core   +1 more source