Results 21 to 30 of about 13,861 (172)
Patients With Pituitary Neuroendocrine Tumours Requiring Neurosurgery -Who Is Referring Them? [PDF]
Clin Endocrinol (Oxf)ABSTRACT Objective Patients living with pituitary neuroendocrine tumours (PitNETs) present with a spectrum of clinical manifestations and often follow a circuitous route to diagnosis, resulting in diagnostic delays. The objective of this study is to identify and report the various sources of referrals for patients who underwent pituitary resection for ...
Ahmed DS +11 more
europepmc +2 more sources
Rheumatic manifestations of acromegaly [PDF]
Остеопороз и остеопатии, 2020 Acromegaly is a chronic endocrine disease characterized by excessive secretion of growth hormone (GH), which, in turn, leads to increased insulin-like growth factor 1 (IGF-1) secretion by the liver.
Taras S. Panevin +2 more
doaj +1 more source
Insulin Resistance in Patients With Acromegaly
Frontiers in Endocrinology, 2019 Acromegaly is characterized by chronic overproduction of growth hormone (GH) that leads to insulin resistance, glucose intolerance and, ultimately, diabetes. The GH-induced sustained stimulation of lipolysis plays a major role not only in the development
Greisa Vila +3 more
doaj +1 more source
Acromegaly without acral anomalies [PDF]
Romanian Journal of Medical Practice, 2021 Early recognition of a pituitary secretor tumor offers a better prognostic; thus acromegaly might be recognized before the actual clinical picture of acromegaly is detectable.
Mara Carsote +6 more
doaj +1 more source
BMC Musculoskeletal Disorders, 2021 Background Acromegaly is a rare disease caused by high serum levels of growth hormone (GH) and insulin-like growth factor 1 (IGF-1), often originating from a pituitary adenoma.
Daisuke Kamakura +8 more
doaj +1 more source
Extra-hepatic Acromegaly [PDF]
US Endocrinology, 2010 After the introduction of somatostatin analogs (LA-SMSA) and the growth hormone (GH) receptor antagonist, pegvisomant (Peg-v) normal serum insulin-like growth factor-1 (IGF-1) concentrations in virtually every patients with acromegaly is possible. The impact of these products on the GH–IGF1 axis is completely different.
Franck, Sanne E. +2 more
openaire +3 more sources
Bone densitometry by radiofrequency echographic multi-spectrometry (REMS) in acromegaly patients
Endokrynologia Polska, 2020 INTRODUCTION: Radiofrequency echographic multi-spectrometry (REMS) is a recently introduced non-ionising technology employed in the evaluation of osteoporosis.
Małgorzata Rolla +3 more
doaj +1 more source
Heat Intolerance and Hyperhidrosis as the only Presenting Manifestations of Acromegaly: A Case Report [PDF]
Journal of Clinical and Diagnostic Research, 2020 Acromegaly is a state of Growth Hormone (GH) excess characterised by coarse facial features, acral enlargement, hyperhidrosis, headache, visual disturbances and visceromegaly. The most common cause of acromegaly is pituitary adenoma.
TN Kamalesh +2 more
doaj +1 more source
Frontiers in Endocrinology, 2019 Introduction: The vitamin D receptor (VDR) gene is one of the most widely studied tumorigenesis-related genes. The primary objective of this study was assessment of possible roles of VDR gene polymorphisms in acromegaly, with regard to the activity of ...
Aleksandra Jawiarczyk-Przybyłowska +5 more
doaj +1 more source
Trends in Endocrinology & Metabolism, 1992 In the majority of cases, acromegaly is due to GH hypersecretion by a somatotroph pituitary tumor. The etiology of acromegaly is not known, and may be related to GHRH hypersecretion, intrinsic pituitary defect, or a combination thereof. Recent physiologic data and molecular biology techniques provide insights into the pathophysiology of this condition.
openaire +3 more sources