Results 31 to 40 of about 23,672 (222)
Trends in Endocrinology & Metabolism, 1992 In the majority of cases, acromegaly is due to GH hypersecretion by a somatotroph pituitary tumor. The etiology of acromegaly is not known, and may be related to GHRH hypersecretion, intrinsic pituitary defect, or a combination thereof. Recent physiologic data and molecular biology techniques provide insights into the pathophysiology of this condition.
openaire +3 more sources
Acromegaly with metastatic renal cell carcinoma: Lung, gluteal and scapular metastasis
Medicine Science, 2018 The association between acromegaly and increased incidence of malignancy has been reported due to high GH and IGF levels. Although the incidence of all malignancies increases in patients with acromegaly, renal cell carcinoma (RCC) has been rarely ...
Ziynet Alphan Uc +3 more
doaj +1 more source
Prevalence of acromegaly in patients with symptoms of sleep apnea.
PLoS ONE, 2017 Acromegaly is a rare disease with nonspecific symptoms with acral enlargement being almost universally present at diagnosis. The estimated prevalence is 40-125 cases/million but targeted universal screening studies have found a higher prevalence (about ...
Gemma Sesmilo +14 more
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Reproductive Biology and Endocrinology, 2023 Background Acromegaly is a disease of growth hormone excess that results in enlargement of extremities, abnormal glucose and lipid metabolism, and gonadal disruption. Manifestations of the disease are insidious and typically lead to a diagnostic delay of
Anamil M. Khiyami +6 more
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Bone densitometry by radiofrequency echographic multi-spectrometry (REMS) in acromegaly patients
Endokrynologia Polska, 2020 INTRODUCTION: Radiofrequency echographic multi-spectrometry (REMS) is a recently introduced non-ionising technology employed in the evaluation of osteoporosis.
Małgorzata Rolla +3 more
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Recent Developments in Capillary and Microchip Electroseparations of Peptides (2023–mid 2025)
ELECTROPHORESIS, EarlyView.ABSTRACT This review presents a comprehensive overview of the developments and applications of high‐performance capillary and microchip electromigration methods (zone electrophoresis in a free solution or in sieving media, isotachophoresis, isoelectric focusing, affinity electrophoresis, electrokinetic chromatography, and electrochromatography) for ...
Václav Kašička
wiley +1 more source
Insulin Resistance in Patients With Acromegaly
Frontiers in Endocrinology, 2019 Acromegaly is characterized by chronic overproduction of growth hormone (GH) that leads to insulin resistance, glucose intolerance and, ultimately, diabetes. The GH-induced sustained stimulation of lipolysis plays a major role not only in the development
Greisa Vila +3 more
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Head &Neck, EarlyView.ABSTRACT Background To evaluate postoperative health‐related quality of life (HRQoL) for pituitary adenoma patients, multidimensional assessment is important. Available data is limited on long‐term follow‐up. Methods Prospectively, 52 nonfunctioning (NFA) and functioning (FA) pituitary adenoma patients were included.
Gonneke E. Joustra +7 more
wiley +1 more source
Guidelines on diagnostics and treatment of acromegaly (draft)
Ожирение и метаболизмWe recommend acromegaly to be ruled in all patients with characteristic changes in appearance (A3). In all patients without characteristic changes in appearance, we recommend to rule out acromegaly, if several clinical signs suspicious for acromegaly are
E. G. Przhiyalkovskaya +25 more
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Luteinizing hormone receptor knockout mouse: What has it taught us?
Andrology, EarlyView.Abstract Luteinizing hormone (LH), along with its agonist choriongonadotropin (hCG) in humans, is the key hormone responsible for the tropic regulation of the gonadal function. LH and hCG act through their cognate receptor, the luteinizing hormone/choriongonadotropin receptor (LHCGR; more appropriately LHR in rodents lacking CG), located in the testis ...
Ilpo T. Huhtaniemi
wiley +1 more source