Results 31 to 40 of about 23,247 (206)
Insulin Resistance in Patients With Acromegaly
Acromegaly is characterized by chronic overproduction of growth hormone (GH) that leads to insulin resistance, glucose intolerance and, ultimately, diabetes. The GH-induced sustained stimulation of lipolysis plays a major role not only in the development
Greisa Vila+3 more
doaj +1 more source
Clinical characteristics and efficacy of acromegaly treatment in the Udmurt Republic
Background: Acromegaly is a severe neuroendocrine disorder caused by chronic overproduction of growth hormone and insulin-like growth factor 1 and associated with a variety of clinical manifestations, debilitating complications and progressive disability,
Guzel M. Nurullina+3 more
doaj +1 more source
Pregnancy and acromegaly [PDF]
Acromegaly is a rare disorder in which, due to the high incidence of secondary hypogonadism, pregnancies are relatively rare. However, some women with acromegaly do get pregnant, which brings along questions about medication, complications and follow-up.
Ammar Muhammad+2 more
openaire +4 more sources
Acromegaly with metastatic renal cell carcinoma: Lung, gluteal and scapular metastasis
The association between acromegaly and increased incidence of malignancy has been reported due to high GH and IGF levels. Although the incidence of all malignancies increases in patients with acromegaly, renal cell carcinoma (RCC) has been rarely ...
Ziynet Alphan Uc+3 more
doaj +1 more source
Management of acromegaly [PDF]
Acromegaly is caused by hypersecretion of growth hormone and resultant overproduction of insulin-like growth factor-1 and is associated with increased mortality and morbidity. Successful treatment modalities have been developed and are used in a multistep approach allowing normal life expectancy as well as improved quality of life in an increasing ...
Sabina Zacharieva+3 more
openaire +3 more sources
Guidelines on diagnostics and treatment of acromegaly (draft)
We recommend acromegaly to be ruled in all patients with characteristic changes in appearance (A3). In all patients without characteristic changes in appearance, we recommend to rule out acromegaly, if several clinical signs suspicious for acromegaly are
E. G. Przhiyalkovskaya+25 more
doaj +1 more source
Something strange started happening to me around 10 years ago. My shoe size grew from 9 to 11, my income permanently dried up, and the girlfriend I was going to marry left after we stopped having sex. It wasn't just the sex, or lack of it. I also dramatically changed, both personally and physically.
openaire +3 more sources
Scenarios of drug exposure and administration as well as detection assays for drugs and methods of sports doping published between 2023 and 2024 are critically reviewed and evaluated in context with the Prohibited List 2024 as established by the World Anti‐Doping Agency.
Mario Thevis+2 more
wiley +1 more source
The Endothelium in Acromegaly [PDF]
Growth hormone (GH) and insulin like growth factor-1 (IGF-1) excess induce well-known deleterious effects on the cardiovascular system, especially after long-term exposition. Acromegaly, a condition of chronic GH and IGF-1 hypersecretion, is frequently associated to cardiovascular complications, although recent studies have shown a reduction in the ...
Maffei, Pietro+4 more
openaire +4 more sources