Results 31 to 40 of about 57,421 (320)

Increased Risk of Hip Fracture in Patients with Acromegaly: A Nationwide Cohort Study in Korea [PDF]

Endocrinology and Metabolism, 2023
Background Acromegaly leads to various skeletal complications, and fragility fractures are emerging as a new concern in patients with acromegaly. Therefore, this study investigated the risk of fractures in Korean patients with acromegaly. Methods We used
Jiwon Kim, Namki Hong, Jimi Choi, Ju Hyung Moon, Eui Hyun Kim, Eun Jig Lee, Sin Gon Kim, Cheol Ryong Ku   +7 more
doaj   +1 more source

Global epidemiology of acromegaly: a systematic review and meta-analysis.

European Journal of Endocrinology, 2021
OBJECTIVE To date, no systematic reviews and meta-analysis on the global epidemiology of acromegaly are available in literature. The aims of this study are to provide a systematic review and a meta-analysis of the global epidemiology of acromegaly and to
S. Crisafulli, N. Luxi, J. Sultana, A. Fontana, F. Spagnolo, G. Giuffrida, F. Ferraù, D. Gianfrilli, A. Cozzolino, M. D. De Martino, F. Gatto, Francesco Barone-Adesi, S. Cannavò, G. Trifirò   +13 more
semanticscholar   +1 more source

Is H19 RNA a Useful Marker of Acromegaly and Its Complications? A Preliminary Study

Biomedicines, 2023
Acromegaly is a rare endocrine disorder caused by somatotroph pituitary adenoma. Besides its typical symptoms, it contributes to the development of cardiovascular, metabolic, and bone comorbidities. H19 RNA is a long non-coding RNA and it is suspected to
Małgorzata Rolla, Aleksandra Jawiarczyk-Przybyłowska, Katarzyna Kolačkov, Agnieszka Zembska, Marek Bolanowski   +4 more
doaj   +1 more source

The Biochemical Diagnosis of Acromegaly

Journal of Clinical Medicine, 2021
Background: The diagnosis of acromegaly still poses a clinical challenge, and prolonged diagnostic delay is common. The most important assays for the biochemical diagnosis and management of acromegaly are growth hormone (GH) and insulin-like growth ...
A. Akirov, H. Masri-Iraqi, I. Dotan, I. Shimon   +3 more
semanticscholar   +1 more source

A Pituitary Society update to acromegaly management guidelines

Pituitary, 2020
Guidelines and consensus statements ensure that physicians managing acromegaly patients have access to current information on evidence-based treatments to optimize outcomes.
M. Fleseriu, B. Biller, P. Freda, M. Gadelha, A. Giustina, L. Katznelson, M. Molitch, S. Samson, C. Strasburger, A. J. van der Lely, S. Melmed   +10 more
semanticscholar   +1 more source

Advances in Research on the Cardiovascular Complications of Acromegaly

Frontiers in Oncology, 2021
Cardiovascular-related complications are one of the most common complications in patients with acromegaly, and can lead to an increased risk of death. Hypertension and cardiomyopathy are the main cardiovascular complications.
Han Yang, Huiwen Tan, He Huang, Jianwei Li   +3 more
semanticscholar   +1 more source

Insulin Like Growth Factor Binding Protein 7 as a Novel Diagnostic Marker in Sera of Iraqi Patients with Acromegaly

مجلة بغداد للعلوم, 2023
The purpose of this study was to measure serum levels of insulin-like growth factor-binding protein (IGFBP7), Insulin-like Growth Factor 1 (IGF-1), Growth Hormone (GH), Interleukin 6 (IL-6) and insulin in acromegaly patients and healthy controls.
Layla Othman Farhan, Baydaa Ahmed Abed, Kashtl Ghasaq J., Isam Noori Salman   +3 more
doaj   +1 more source

Prevalence of vertebral fractures and serum sclerostin levels in acromegaly

Endocrine, 2021
An increased prevalence of vertebral fractures (VFs) has been reported in previous studies. The aim of this study was to evaluate the association between bone mineral density (BMD), bone turnover markers, serum sclerostin levels, and vertebral fractures (
M. M. Uygur, D. Yazıcı, Onur Buğdaycı, D. Yavuz   +3 more
semanticscholar   +1 more source

The role of stereotactic radiosurgery in the multimodal management of growth hormone–secreting pituitary adenomas [PDF]

, 2010
Growth hormone (GH)–secreting pituitary adenomas represent a common source of GH excess in patients with acromegaly. Whereas surgical extirpation of the culprit lesion is considered first-line treatment, as many as 19% of patients develop recurrent ...
Liu, Charles Y., Stapleton, Christopher J., Weiss, Martin H.   +2 more
core   +1 more source

Feline hypersomatotropism and acromegaly tumorigenesis: a potential role for the AIP gene [PDF]

, 2017
Acromegaly in humans is usually sporadic, however up to 20% of familial isolated pituitary adenomas are caused by germline sequence variants of the aryl-hydrocarbon-receptor interacting protein (AIP) gene.
Catchpole, B, Church, D B, Forcada, Y, Fowkes, R C, Niessen, S J M, Scudder, C J   +5 more
core   +1 more source