Results 31 to 40 of about 43,416 (273)

Growth hormone nadir during oral glucose load depends on waist circumference, gender and age: normative data in 231 healthy subjects. [PDF]

, 2011
Objective  (i) To analyse the predictors of GH suppression after standard glucose load (oGTT) in the healthy population and (ii) to establish the 97th percentile of GH nadir post-oGTT according to these variables.
AURIEMMA, RENATA SIMONA, COLAO, ANNAMARIA, GALDIERO, MARIANO, GRASSO, LUDOVICA FRANCESCA STELLA, LOMBARDI, GAETANO, PIVONELLO, CLAUDIA, PIVONELLO, ROSARIO, SAVASTANO, SILVIA   +7 more
core   +1 more source

Pasireotide for the Medical Management of Feline Hypersomatotropism [PDF]

, 2015
BACKGROUND: Feline hypersomatotropism (HST) is a cause of diabetes mellitus in cats. Pasireotide is a novel multireceptor ligand somatostatin analog that improves biochemical control of humans with HST.
Abraham, Adams, Alt, Appleton, Bhayana, Bruns, Castillo, Church, Colao, Colao, Cuevas-Ramos, Fedele, Fernandez-Rodriguez, Fougner, Golor, Henry, Hofland, Juul, Katznelson, Kvols, Lamb, Lamberts, Maxwell, Meij, Miller, Murray, Myers, Niessen, Niessen, Niessen, Niessen, Petrus, Polska, Rand, Ray, Schmid, Schmid, Sheppard, Slingerland, Sohmiya, Starkey, Stolk, Taboada, Wajchenberg, Zatelli, Zou   +45 more
core   +2 more sources

Pasireotide Long-Acting Release Treatment for Diabetic Cats with Underlying Hypersomatotropism [PDF]

, 2017
BACKGROUND: Long‐term medical management of hypersomatotropism (HS) in cats has proved unrewarding. Pasireotide, a novel somatostatin analogue, decreases serum insulin‐like growth factor 1 (IGF‐1) and improves insulin sensitivity in cats with HS when ...
Abraham, Berg, Bruns, Church, Colao, Colao, Combes, Cozzi, Dowling, Dunning, Feelders, Freda, Gadelha, Henry, Hofland, Hubina, Hussaini, Jaffe, Katznelson, Kurosaki, Lamb, Laron, Ma, Meij, Meij, Myers, Niessen, Niessen, Niessen, Patel, Petersenn, Peterson, Reubi, Reusch, Reusch, Sathyapalan, Schaefer, Scudder, Shanik, Slingerland, Slingerland, Theodoropoulou, Tyson, Zambre   +43 more
core   +3 more sources

Acromegaly presenting with myelopathy due to ossification of posterior longitudinal ligament: a case report

BMC Musculoskeletal Disorders, 2021
Background Acromegaly is a rare disease caused by high serum levels of growth hormone (GH) and insulin-like growth factor 1 (IGF-1), often originating from a pituitary adenoma.
Daisuke Kamakura, Katsunori Fukutake, Kazumasa Nakamura, Shintaro Tsuge, Keiji Hasegawa, Naobumi Tochigi, Akihito Wada, Tetsuo Mikami, Hiroshi Takahashi   +8 more
doaj   +1 more source

Serum N-Terminal Type III Procollagen Propeptide: An Indicator of Growth Hormone Excess and Response to Treatment in Feline Hypersomatotropism [PDF]

, 2016
BACKGROUND: N‐terminal type III procollagen propeptide (PIIINP) is a biomarker of soft tissue proliferation. Hypersomatotropism (HS) is associated with soft tissue proliferation.
Church, D B, Forcada, Y, Kenny, P J, Keyte, S V, Niessen, S J M   +4 more
core   +3 more sources

Growth Hormone (GH)-Releasing Peptide Stimulation of GH Release from Human Somatotroph Adenoma Cells: Interaction with GH-Releasing Hormone, Thyrotropin- Releasing Hormone, and Octreotide. [PDF]

, 1994
The synthetic hexapeptide GH-releasing peptide (GHRP; His-D-Trp-Ala-Trp-D-Phe-Lys-NH2) specifically stimulates GH secretion in humans in vivo and in animals in vitro and in vivo via a still unknown receptor and mechanism.
Brockmeier, S., Lange, M., Müller, Otto-Albrecht, Renner, U., Schopohl, Jochen, Stalla, G. K., Strasburger, Christian J., Werder, K. von   +7 more
core   +1 more source

Association of Vitamin D Receptor Polymorphisms With Activity of Acromegaly, Vitamin D Status and Risk of Osteoporotic Fractures in Acromegaly Patients

Frontiers in Endocrinology, 2019
Introduction: The vitamin D receptor (VDR) gene is one of the most widely studied tumorigenesis-related genes. The primary objective of this study was assessment of possible roles of VDR gene polymorphisms in acromegaly, with regard to the activity of ...
Aleksandra Jawiarczyk-Przybyłowska, Jowita Halupczok-Żyła, Katarzyna Kolačkov, Łukasz Gojny, Agnieszka Zembska, Marek Bolanowski   +5 more
doaj   +1 more source

Rheumatic manifestations of acromegaly [PDF]

Остеопороз и остеопатии, 2020
Acromegaly is a chronic endocrine disease characterized by excessive secretion of growth hormone (GH), which, in turn, leads to increased insulin-like growth factor 1 (IGF-1) secretion by the liver.
Taras S. Panevin, Lyudmila I. Alekseeva, Galina A. Melnichenko   +2 more
doaj   +1 more source

Gene Expression Signature in Adipose Tissue of Acromegaly Patients. [PDF]

, 2014
To study the effect of chronic excess growth hormone on adipose tissue, we performed RNA sequencing in adipose tissue biopsies from patients with acromegaly (n = 7) or non-functioning pituitary adenomas (n = 11).
Barkan, Ariel L, Bridges, Dave, Chandler, William F, Hochberg, Irit, Saltiel, Alan R, Tran, Quynh T   +5 more
core   +10 more sources

Extra-hepatic Acromegaly [PDF]

US Endocrinology, 2010
After the introduction of somatostatin analogs (LA-SMSA) and the growth hormone (GH) receptor antagonist, pegvisomant (Peg-v) normal serum insulin-like growth factor-1 (IGF-1) concentrations in virtually every patients with acromegaly is possible. The impact of these products on the GH–IGF1 axis is completely different.
Franck, Sanne E., van der Lely, Aart Jan, Neggers, Sebastian   +2 more
openaire   +3 more sources