Results 41 to 50 of about 38,436 (213)
BMC Musculoskeletal Disorders, 2021 Background Acromegaly is a rare disease caused by high serum levels of growth hormone (GH) and insulin-like growth factor 1 (IGF-1), often originating from a pituitary adenoma.
Daisuke Kamakura +8 more
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Clinical characteristics and efficacy of acromegaly treatment in the Udmurt Republic
Alʹmanah Kliničeskoj Mediciny, 2022 Background: Acromegaly is a severe neuroendocrine disorder caused by chronic overproduction of growth hormone and insulin-like growth factor 1 and associated with a variety of clinical manifestations, debilitating complications and progressive disability,
Guzel M. Nurullina +3 more
doaj +1 more source
PituitaryPurpose A series of consensus guidelines on medical treatment of acromegaly have been produced in the last two decades. However, little information is available on their application in clinical practice. Furthermore, international standards of acromegaly
Acromegaly · Octreotide +21 more
semanticscholar +1 more source
Serum Levels of Asprosin, a Novel Adipokine, Are Significantly Lowered in Patients with Acromegaly
International Journal of Endocrinology, 2020 Background. Asprosin is a novel identified adipokine secreted mainly by white adipose tissue, which is elevated in metabolic diseases such as diabetes and obesity.
Xiaoan Ke +8 more
doaj +1 more source
MANAGEMENT OF ENDOCRINE DISEASE: Does gender matter in the management of acromegaly.
European Journal of Endocrinology, 2020 Gonadal steroids modulate the effects of GH, with oestrogens attenuating and androgens augmenting GH action. Whether these divergent effects influence the clinical manifestation, management and prognosis of acromegaly have not been carefully reviewed ...
N. Lenders, A. McCormack, K. Ho
semanticscholar +1 more source
Acromegaly with metastatic renal cell carcinoma: Lung, gluteal and scapular metastasis
Medicine Science, 2018 The association between acromegaly and increased incidence of malignancy has been reported due to high GH and IGF levels. Although the incidence of all malignancies increases in patients with acromegaly, renal cell carcinoma (RCC) has been rarely ...
Ziynet Alphan Uc +3 more
doaj +1 more source
Clinical MEN-1 Among a Large Cohort of Patients With Acromegaly
Journal of Clinical Endocrinology and Metabolism, 2020 Context Clinical multiple endocrine neoplasia type 1 (MEN-1) is diagnosed by the presence of at least 2 MEN-1–associated tumors. Many patients with acromegaly and clinical MEN-1 yield negative testing for MEN1 mutations.
L. Nachtigall +11 more
semanticscholar +1 more source
Endocrinology, Diabetes & Metabolism Case Reports, 2017 A male patient presented at the age of 30 with classic clinical features of acromegaly and was found to have elevated growth hormone levels, not suppressing during an oral glucose tolerance test.
Nikolaos Kyriakakis +6 more
doaj +1 more source
Mortality in acromegaly decreased in the last decade: a systematic review and meta-analysis.
European Journal of Endocrinology, 2018 OBJECTIVE To compare the acromegaly mortality rates with those expected for the general population from studies published before and after 2008. METHODS We performed a systematic review and included observational studies in which the number of deaths ...
Fernanda Bolfi +3 more
semanticscholar +1 more source
European Journal of Endocrinology, 2020 The literature on an association between acromegaly and cancer is particularly abundant on either colorectal cancer or thyroid cancer, and an endless debate is ongoing whether patients with acromegaly should be submitted to specific oncology screening ...
M. Terzolo +4 more
semanticscholar +1 more source