Results 41 to 50 of about 57,421 (320)

CONDITION OF THE MUSCULOSKELETAL SYSTEM IN PATIENTSWITH ACROMEGALY.

Остеопороз и остеопатии, 2010
Despite the relatively low incidence of acromegaly (60-70 cases per I million inhabitants), this disease has a special place among the heterogeneous group of diseases that lead to the defeat of the locomotor apparatus.
A S Fedotova, N N Molitvoslovova, L I Alekseeva, L Ya Rozhinskaya, A. S. Fedotova, N. N. Molitvoslovova, L. I. Alexeeva, L. Y. Rozhinskaya   +7 more
doaj   +1 more source

Excessive growth hormone expression in male GH transgenic mice adversely alters bone architecture and mechanical strength [PDF]

, 2015
Patients with acromegaly have a higher prevalence of vertebral fractures despite normal bone mineral density (BMD), suggesting that GH overexpression has adverse effects on skeletal architecture and strength. We used giant bovine GH (bGH) transgenic mice
Chavassieux, P, Chenu, C, Hopkinson, M, Javaheri, B, Kopchick, J, Korbonits, M, Lim, SV, List, E, Marenzana, M, Pereira, M, Roux, J   +10 more
core   +1 more source

Time spent with cats is never wasted: Lessons learned from feline acromegalic cardiomyopathy, a naturally occurring animal model of the human disease [PDF]

, 2018
BackgroundIn humans, acromegaly due to a pituitary somatotrophic adenoma is a recognized cause of increased left ventricular (LV) mass. Acromegalic cardiomyopathy is incompletely understood, and represents a major cause of morbidity and mortality.
A Colao, A Colao, A Colao, A Colao, A Colao, A Colao, A Colao, A Colao, A Mestron, A Piovesan, AC Dirtu, AM Pereira, B Posch, BJ Maron, BPP Meij, BR Bond, C Paige, C-Y Liu, CJL Little, CR Lamb, David B. Church, David J. Connolly, DJ Connolly, F Fracassi, G Jacobs, G Lombardi, G Lombardi, J Dal, J Gilbert, JA Myers, JK Sangster, JM Fletcher, JR Payne, JT Lie, Kieran Borgeat, LJ Wilkie, Lois Wilkie, M Galderisi, M Lesser, M Maxie Grant, M Nishiki, M Rosca, M-LL Jaffrain-Rea, MD Kittleson, ME Peterson, ME Peterson, NJ Pereira, Norelene Harrington, NS Moise, NS Moise, O Kershaw, OM Dekkers, P Menaut, PR Fox, PR Fox, PR Fox, PR Fox, PR Fox, R Baldelli, R Gostelow, R Pivonello, RC Weichselbaum, S Brown, S Fazio, S Fazio, S Fazio, S Fieffe, S Murarka, S Niessen, SJM Niessen, SJM Niessen, SJM Niessen, SK Liu, SK Liu, Stijn J. M. Niessen, SV Keyte, T Wagner, T. Rosol, Vincenzo Lionetti, Virginia Luis Fuentes, WL McGuffin   +80 more
core   +2 more sources

Acromegaly, Mr Punch and caricature. [PDF]

, 1996
The origin of Mr Punch from the Italian Pulcinella of the Commedia dell'arte is well known but his feature, large hooked nose, protruding chin, kyphosis and sternal protrusion all in an exaggerated form also suggest the caricature of an acromegalic. This
Armstrong R, Coues W P, Cruickshank G, David Bryson, De Souze-Leite J D, Dumas P, Ferrier D, Fritsche, Gourevitch D, Grossman A, Hutchinson W, Jewesbury R C, Levine D, Lucie-Smith E, Marie P, Mark L P, Soques A, Sternberg M, Toms K, Weinberg S J, Wells C   +20 more
core   +2 more sources

Acromegaly without acral anomalies [PDF]

Romanian Journal of Medical Practice, 2021
Early recognition of a pituitary secretor tumor offers a better prognostic; thus acromegaly might be recognized before the actual clinical picture of acromegaly is detectable.
Mara Carsote, Florica Sandru, Diana Elena Rentea, Claudia Mehedintu, Stefania Zugravu, Corina Chirita, Mihai Cristian Dumitrascu   +6 more
doaj   +1 more source

Acromegaly: an endocrine society clinical practice guideline.

Journal of Clinical Endocrinology and Metabolism, 2014
OBJECTIVE The aim was to formulate clinical practice guidelines for acromegaly. PARTICIPANTS The Task Force included a chair selected by the Endocrine Society Clinical Guidelines Subcommittee (CGS), five experts in the field, and a methodologist.
L. Katznelson, E. Laws, S. Melmed, M. Molitch, M. Murad, A. Utz, J. Wass   +6 more
semanticscholar   +1 more source

Prolonged Diagnostic Delay in Acromegaly is Associated with Increased Morbidity and Mortality.

European Journal of Endocrinology, 2020
CONTEXT Clinical features of acromegaly develop insidiously. Its diagnosis may therefore be delayed. OBJECTIVE Our aim was to study diagnostic delay and its impact on morbidity and mortality in a nationwide cohort of patients with acromegaly.
D. Esposito, O. Ragnarsson, G. Johannsson, Daniel S Olsson   +3 more
semanticscholar   +1 more source

Effects of Pegvisomant and Pasireotide LAR on vertebral fractures in acromegaly resistant to First-Generation SRLs.

Journal of Clinical Endocrinology and Metabolism, 2020
PURPOSE Osteopathy is an emerging complication of acromegaly. In somatostatin receptor ligands (SRL)-resistant patients, Pegvisomant (PegV) and Pasireotide LAR (Pasi) are used for acromegaly treatment, but their effect on skeletal health is still not ...
S. Chiloiro, A. Giampietro, S. Frara, C. Bima, F. Donfrancesco, Cara M. Fleseriu, A. Pontecorvi, A. Giustina, M. Fleseriu, L. De Marinis, A. Bianchi   +10 more
semanticscholar   +1 more source

Systemic Complications of Acromegaly and the Impact of the Current Treatment Landscape: An Update.

Endocrine reviews, 2018
Acromegaly is a chronic systemic disease with many complications and is associated with increased mortality when not adequately treated. Substantial advances in acromegaly treatment, as well as in the treatment of many of its complications, mainly ...
M. Gadelha, L. Kasuki, D. Lim, M. Fleseriu   +3 more
semanticscholar   +1 more source

Acromegaly [PDF]

The Journal of Nervous and Mental Disease, 1895
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openaire   +2 more sources