Results 41 to 50 of about 23,247 (206)

Incidence of bronchiectasis in patients with acromegaly: a cohort study

Frontiers in Endocrinology
ObjectiveAssociations between acromegaly and several respiratory diseases, such as obstructive lung disease or sleep apnea, have been suggested, but the relationship between bronchiectasis and acromegaly is unclear.
Hyun-Il Gil, Kyungdo Han, Sangmo Hong, Cheol-Young Park   +3 more
doaj   +1 more source

Diagnostic challenges and management of a patient with acromegaly due to ectopic growth hormone-releasing hormone secretion from a bronchial carcinoid tumour

Endocrinology, Diabetes & Metabolism Case Reports, 2017
A male patient presented at the age of 30 with classic clinical features of acromegaly and was found to have elevated growth hormone levels, not suppressing during an oral glucose tolerance test.
Nikolaos Kyriakakis, Jacqueline Trouillas, Mary N Dang, Julie Lynch, Paul Belchetz, Márta Korbonits, Robert D Murray   +6 more
doaj   +1 more source

Evidence‐based management strategies for endocrine complications after pituitary adenoma surgery

Ibrain, EarlyView.
Based on the PIPOST (Population, Intervention, Professional, Outcome, Setting, and Type of Evidence) framework, evidence‐based medicine questions were developed, and a top‐down search was conducted according to the 6S model of the evidence pyramid. The literature sources were best practices, guidelines, expert consensuses, systematic reviews, meta ...
Xiaoju Miao, Zhongmin Fu, Xian Luo, Jun Wang, Zhangzhu Ren, Yuanyuan Wang, Guoping Mei, Shunwu Xiao   +7 more
wiley   +1 more source

A Zebrafish Acromegaly Model Elevates DNA Damage and Impairs DNA Repair Pathways

Biology, 2018
Acromegaly is a pathological condition due to excess growth hormone (GH) secretion. Acromegaly patients exhibit a deterioration of health and many associated complications, such as cardiovascular issues, arthritis, kidney diseases, muscular weakness, and
Abdalla Elbialy, Shuichi Asakawa, Shugo Watabe, Shigeharu Kinoshita   +3 more
doaj   +1 more source

Automatic Detection for Acromegaly Using Hand Photographs: A Deep-Learning Approach

IEEE Access, 2021
Machine learning assisted diagnosis of acromegaly from facial photographs has been proved feasible in recent years. According to our previous research, facial and limb changes exist in patients with acromegaly at early stage.
Chengbin Duan, Wenli Chen, Shun Yao, Zhigang Mao, Zongming Wang, Bin Hu, Haosen Jiao, Dimin Zhu, Yonghong Zhu, Haijun Wang   +9 more
doaj   +1 more source

Advances in the Role of Antimicrobial Peptides in the Management of Sexually Transmitted Infections

Journal of Clinical Laboratory Analysis, EarlyView.
The article reviews recent advancements in the use of antimicrobial peptides (AMPs) for the treatment and prevention of sexually transmitted infections (STIs), with a particular focus on research progress in combating infections such as gonorrhea, HIV, HSV, and Chlamydia, as well as the challenges and future directions in this field.
Shuangwen Xiao, Wei Zuo, Qing Xiang, Yafeng Xie, Yongjian Xiao   +4 more
wiley   +1 more source

Unexplained massive pulmonary embolism in acromegaly patient: A case report

Clinical Case Reports
Key Clinical Message Our case highlights the importance of recognizing acromegaly as a potential risk factor for venous thromboembolism (VTE). Despite a thorough thrombophilia workup yielding unremarkable results, further research is warranted to ...
Usamah Al‐Anbagi, Shybin Usman, Abdulrahman Saad, Abdulqadir J. Nashwan   +3 more
doaj   +1 more source

Nanoparticle Therapeutics in Clinical Perspective: Classification, Marketed Products, and Regulatory Landscape

Small, EarlyView.
This review presents a detailed overview of clinically approved nanoparticle therapeutics, classifying them by type and discussing their unique advantages in drug delivery. It highlights regulatory challenges across global markets and emphasizes the need for adaptive approval pathways.
Nimeet Desai, Dhwani Rana, Mitali Patel, Neha Bajwa, Rajendra Prasad, Lalitkumar K. Vora   +5 more
wiley   +1 more source

Biomarkers of Cellular Senescence in Type 2 Diabetes Mellitus

Aging Cell, EarlyView.
In cohorts of lean controls, obese participants without Type 2 Diabetes Mellitus (T2DM) and obese T2DM participants, we find that T‐cell expression of senescence biomarkers is altered only in the T2DM participants and not with obesity alone. Moreover, high T‐cell p16 expression in the T2DM participants is associated with impaired bone cortical indices.
Caroline Hoong, Joshua N. Farr, David G. Monroe, Thomas A. White, Elizabeth J. Atkinson, Amanda Tweed, Allyson K. Palmer, Nathan K. LeBrasseur, Jad G. Sfeir, Sundeep Khosla   +9 more
wiley   +1 more source

Hypertension and Acromegaly [PDF]

Endocrinology and Metabolism Clinics of North America, 2019
Hypertension is one of the most frequent complications in acromegaly, with a median frequency of 33.6% (range, 11%-54.7%). Although the pathogenesis has not been fully elucidated, it probably results from concomitant factors leading to expansion of extracellular fluid volume, increase of peripheral vascular resistance, and development of sleep apnea ...
Puglisi S, Terzolo M
openaire   +4 more sources