Results 61 to 70 of about 57,421 (320)
Acromegaly with metastatic renal cell carcinoma: Lung, gluteal and scapular metastasis
Medicine Science, 2018 The association between acromegaly and increased incidence of malignancy has been reported due to high GH and IGF levels. Although the incidence of all malignancies increases in patients with acromegaly, renal cell carcinoma (RCC) has been rarely ...
Ziynet Alphan Uc +3 more
doaj +1 more source
Cutis verticis gyrata in a patient with multiple basal cell carcinomas; case presentation and review of the literature [PDF]
, 2016 Cutis verticis gyrata is a rare disease characterized by convoluted folds and deep furrows of the scalp, resembling the gyri and sulci of the cerebral cortex.
Benea, Vasile +6 more
core +4 more sources
Management of acromegaly [PDF]
F1000 Medicine Reports, 2010 Acromegaly is caused by hypersecretion of growth hormone and resultant overproduction of insulin-like growth factor-1 and is associated with increased mortality and morbidity. Successful treatment modalities have been developed and are used in a multistep approach allowing normal life expectancy as well as improved quality of life in an increasing ...
Sabina Zacharieva +3 more
openaire +3 more sources
Gene Expression Signature in Adipose Tissue of Acromegaly Patients. [PDF]
, 2014 To study the effect of chronic excess growth hormone on adipose tissue, we performed RNA sequencing in adipose tissue biopsies from patients with acromegaly (n = 7) or non-functioning pituitary adenomas (n = 11).
Barkan, Ariel L +5 more
core +9 more sources
Acromegaly: pathogenesis & treatment [PDF]
, 2019 Acromegaly is a multi-system disorder whose etiology is most often traced back to a growth hormone-secreting pituitary adenoma (PA). Growth hormone (GH) secretion promotes insulin-like growth factor 1 (IGF-1) release from peripheral tissues, leading to ...
Tilvawala, Megha
core
Differential Tissue Response to Growth Hormone in Mice [PDF]
, 2018 Growth hormone (GH) has been shown to act directly on multiple tissues throughout the body. Historically, it was believed that GH acted directly in the liver and only indirectly in other tissues via insulin‐like growth hormone 1 (IGF‐1).
Banerjee, Ronadip R. +4 more
core +2 more sources
Nutrition in Clinical Practice, EarlyView.Abstract Somatostatin is a naturally occurring polypeptide hormone that exerts its effect on the gastrointestinal tract by reducing exocrine and endocrine secretion, resulting in decreased motility, gastric emptying, splanchnic blood flow, fat absorption, lymphatic flow, and gallbladder contraction.
Bailey Dunn +4 more
wiley +1 more source
BMJ, 2007 Something strange started happening to me around 10 years ago. My shoe size grew from 9 to 11, my income permanently dried up, and the girlfriend I was going to marry left after we stopped having sex. It wasn't just the sex, or lack of it. I also dramatically changed, both personally and physically.
openaire +3 more sources
The Endothelium in Acromegaly [PDF]
Frontiers in Endocrinology, 2019 Growth hormone (GH) and insulin like growth factor-1 (IGF-1) excess induce well-known deleterious effects on the cardiovascular system, especially after long-term exposition. Acromegaly, a condition of chronic GH and IGF-1 hypersecretion, is frequently associated to cardiovascular complications, although recent studies have shown a reduction in the ...
Maffei, Pietro +4 more
openaire +4 more sources
Local Growth Hormone Facilitates Aging of the Colon Epithelial Microenvironment
Aging Cell, EarlyView.Local growth hormone (GH) is expressed and secreted by senescent cells in the aging human colon. GH triggers epithelial‐to‐mesenchymal transition and activates colon cell motility by regulating extracellular matrix proteins, inducing cytoskeleton rearrangement and altering cell motility protein phosphorylation.
Vera Chesnokova +8 more
wiley +1 more source