Results 61 to 70 of about 23,247 (206)
Abstract Hyperhidrosis is an under‐reported and under‐treated condition that causes significant patient morbidity. Secondary causes require consideration, but the vast majority of cases are idiopathic. The condition is encountered by a range of clinicians, including neurologists, dermatologists and endocrinologists, and it pays to be familiar with the ...
Mitchell J. Lycett, Karl Ng
wiley +1 more source
ABSTRACT Background Sotos syndrome (SoS) is a rare genetic disorder characterised by physical overgrowth and by frequent intellectual disability and comorbidity with neurodevelopmental disorders. A recent study documented a specific cognitive profile of SoS.
Niccolò Butti+5 more
wiley +1 more source
Acromegaly is a rare disease with increased growth hormone secretion most often caused by pituitary adenoma. Not adequately treated acromegaly may lead to early death related to increased rates of acute cardiovascular events, sleep apnea, metabolic ...
I. D. Chikh+3 more
doaj +1 more source
New insights in cellular senescence: The pituitary model
Senescence is a pivotal process in pituitary tumorigenesis. Recent advances have elucidated the complex mechanisms by which key factors, including IL‐6, establish and maintain senescence in these tumors. Given the critical role of senescence and the development of novel techniques to detect senescent cells, the identification of biomarkers and the ...
Florencia Herbstein+8 more
wiley +1 more source
Acromegaly with Normal Insulin-Like Growth Factor-1 Levels and Congestive Heart Failure as the First Clinical Manifestation [PDF]
The leading cause of morbidity and mortality in patients with acromegaly is cardiovascular complications. Myocardial exposure to excessive growth hormone can cause ventricular hypertrophy, hypertension, arrhythmia, and diastolic dysfunction.
Hyae Min Lee+8 more
doaj +1 more source
Abstract Patients with gastroenteropancreatic–neuroendocrine tumors (GEP‐NETs) may present skeletal fragility that might be related to multiple factors, including bone metastases, vitamin D deficiency, hormone secretion, and disease treatments. This study examines the prevalence and determinants of fragility fractures in low grading (G1‐G2) GEP‐NETs ...
Alessandro Brunetti+15 more
wiley +1 more source
Expression of microRNA related to bone remodeling regulation in plasma in patients with acromegaly
Backgraund. MiсroRNA are small regulatory factors that regulate gene expression by post-transcriptional regulation of mRNA, playing an important role in numerous cellular processes including organogenesis, apoptosis, cell proliferation and ...
Tatiana A. Grebennikova+6 more
doaj +1 more source
Objectives To evaluate the glomerular ultrastructural changes associated with diabetic nephropathy and quantify glomerular vascular endothelial growth factor‐A expression in cats with diabetes mellitus compared to controls. Materials and Methods Transmission electron microscopy was performed to evaluate glomerular ultrastructural changes, including ...
H. Reyes‐Hughes+6 more
wiley +1 more source
Biomarkers of acromegaly [PDF]
The papers of Kiseljak-Vassiliades et al. [1] and Selek et al. [2] published in this issue are significant because they focus on an important and unresolved problem of pituitary tumor prognosis, progression, and treatment. Many years ago, pituitary tumors were classified based only on their tinctorial properties using the hematoxylin—eosin stain and ...
Kalman Kovacs+2 more
openaire +2 more sources
ABSTRACT The aim of this systematic review was to investigate the association between craniofacial changes and growth hormone (GH) therapy among children and adolescents with GH deficiency or idiopathic short stature (ISS). The PRISMA guideline was followed to carry out all stages of this review.
Raul Borges Nascimento+3 more
wiley +1 more source