Results 71 to 80 of about 41,662 (214)
Orthodontics &Craniofacial Research, EarlyView.ABSTRACT The aim of this systematic review was to investigate the association between craniofacial changes and growth hormone (GH) therapy among children and adolescents with GH deficiency or idiopathic short stature (ISS). The PRISMA guideline was followed to carry out all stages of this review.
Raul Borges Nascimento +3 more
wiley +1 more source
A UK single‐center pilot experience using a novel robotic inchworm colonoscopy system
DEN Open, Volume 6, Issue 1, April 2026.Abstract Introduction Colonoscopy is the gold standard investigation in the lower gastrointestinal tract. However, 75% of patients can experience pain with moderate sedation. The application of robotic technology aims to overcome difficulties faced including better utilization of rooms for advanced procedures and to achieve a complete colonoscopy in ...
Jabed F. Ahmed +4 more
wiley +1 more source
Expression of microRNA related to bone remodeling regulation in plasma in patients with acromegaly
Ожирение и метаболизм, 2017 Backgraund. MiсroRNA are small regulatory factors that regulate gene expression by post-transcriptional regulation of mRNA, playing an important role in numerous cellular processes including organogenesis, apoptosis, cell proliferation and ...
Tatiana A. Grebennikova +6 more
doaj +1 more source
Protein Science, Volume 34, Issue 8, August 2025.Abstract Aberrant human growth hormone (GH) expression has been increasingly linked to poor outcomes in certain cancers and reduced health span. GH receptor (GHR) signal transduction activates signaling pathways that promote cell proliferation and survival, contributing to tumor progression.
Yue Wang +5 more
wiley +1 more source
Acromegaly with Normal Insulin-Like Growth Factor-1 Levels and Congestive Heart Failure as the First Clinical Manifestation [PDF]
Endocrinology and Metabolism, 2015 The leading cause of morbidity and mortality in patients with acromegaly is cardiovascular complications. Myocardial exposure to excessive growth hormone can cause ventricular hypertrophy, hypertension, arrhythmia, and diastolic dysfunction.
Hyae Min Lee +8 more
doaj +1 more source
Real-world comorbidities and treatment patterns of patients with acromegaly in two large US health plan databases [PDF]
, 2012 Acromegaly is a rare, chronic, and debilitating disease that results from excessive growth hormone production. Clinically, this disease is associated with enlargement of soft tissue, excessive skeletal growth, and increased risk of cardiovascular disease.
Elisabeth Le Nestour +3 more
core +1 more source
Clinical Endocrinology, Volume 103, Issue 2, Page 201-208, August 2025.ABSTRACT Objective Detecting hypotonic urine (specific gravity < 1005 g/L) is crucial for the early identification of arginine vasopressin deficiency (AVP‐deficiency), a common complication after pituitary surgery. This study aimed to evaluate the agreement between urine specific gravity measurements taken by patients using urine test strips and those ...
Jeanne‐Marie Nollen +7 more
wiley +1 more source
AIP and MEN1 mutations and AIP immunohistochemistry in pituitary adenomas in a tertiary referral center. [PDF]
, 2019 Background: Pituitary adenomas have a high disease burden due to tumor growth/ invasion and disordered hormonal secretion. Germline mutations in genes such as MEN1 and AIP are associated with early onset of aggressive pituitary adenomas that can be ...
Cano González, David A. +2 more
core
Journal of Intellectual Disability Research, Volume 69, Issue 8, Page 664-674, August 2025.ABSTRACT Background Sotos syndrome (SoS) is a rare genetic disorder characterised by physical overgrowth and by frequent intellectual disability and comorbidity with neurodevelopmental disorders. A recent study documented a specific cognitive profile of SoS.
Niccolò Butti +5 more
wiley +1 more source
TRH: Pathophysiologic and clinical implications [PDF]
, 1985 Thyrotropin releasing hormone is thought to be a tonic stimulator of the pituitary TSH secretion regulating the setpoint of the thyrotrophs to the suppressive effect of thyroid hormones. The peptide stimulates the release of normal and elevated prolactin.
A. Enjalbert +82 more
core +1 more source