Results 71 to 80 of about 57,421 (320)

Mortality in acromegaly decreased in the last decade: a systematic review and meta-analysis.

European Journal of Endocrinology, 2018
OBJECTIVE To compare the acromegaly mortality rates with those expected for the general population from studies published before and after 2008. METHODS We performed a systematic review and included observational studies in which the number of deaths ...
Fernanda Bolfi, A. F. Neves, C. Boguszewski, V. S. Nunes-Nogueira   +3 more
semanticscholar   +1 more source

MANAGEMENT OF ENDOCRINE DISEASE: Does gender matter in the management of acromegaly.

European Journal of Endocrinology, 2020
Gonadal steroids modulate the effects of GH, with oestrogens attenuating and androgens augmenting GH action. Whether these divergent effects influence the clinical manifestation, management and prognosis of acromegaly have not been carefully reviewed ...
N. Lenders, A. McCormack, K. Ho
semanticscholar   +1 more source

Guidelines on diagnostics and treatment of acromegaly (draft)

Ожирение и метаболизм
We recommend acromegaly to be ruled in all patients with characteristic changes in appearance (A3). In all patients without characteristic changes in appearance, we recommend to rule out acromegaly, if several clinical signs suspicious for acromegaly are
E. G. Przhiyalkovskaya, N. G. Mokrysheva, E. A. Troshina, G. A. Melnichenko, I. I. Dedov, M. B. Antsiferov, L. I. Astafieva, T. P. Bardymova, Zh. E. Belaya, G. R. Vagapova, S. Yu. Vorotnikova, A. Yu. Grigoriev, E. N. Grineva, L. K. Dzeranova, I. A. Ilovaiskaya, P. L. Kalinin, A. M. Lapshina, A. S. Lutsenko, E. O. Mamedova, E. I. Marova, M. A. Perepelova, E. A. Pigarova, V. S. Pronin, L. Ya. Rozhinskaya, Yu. Yu. Trunin, A. S. Shutova   +25 more
doaj   +1 more source

Luteinizing hormone receptor knockout mouse: What has it taught us?

Andrology, EarlyView.
Abstract Luteinizing hormone (LH), along with its agonist choriongonadotropin (hCG) in humans, is the key hormone responsible for the tropic regulation of the gonadal function. LH and hCG act through their cognate receptor, the luteinizing hormone/choriongonadotropin receptor (LHCGR; more appropriately LHR in rodents lacking CG), located in the testis ...
Ilpo T. Huhtaniemi
wiley   +1 more source

Heart failure is common in diabetic cats : findings from a retrospective case-controlled study in first-opinionpractice [PDF]

, 2007
Diabetes mellitus is common in the cat and the prevalence of this condition appears to be increasing (Peterson 1998,Rand and Marshall 2004, Rand and others 2004). The prognosis for cats with diabetes mellitus in first opinion practice has received little
Blue Skies Research Grant - RCVS Trust (Funder), Gettinby, G., Little, C.J.L.   +2 more
core   +1 more source

Society for Endocrinology Clinical Practice Guideline for the Evaluation of Androgen Excess in Women

Clinical Endocrinology, EarlyView.
ABSTRACT Context Androgen excess is common in women and refers to clinical or biochemical evidence of elevated androgenic steroids such as testosterone. It is associated with underlying polycystic ovary syndrome in the majority of cases. However severe androgen excess is less common and may indicate the presence of underlying adrenal or ovarian ...
Yasir S. Elhassan, James M. Hawley, Leanne Cussen, Ali Abbara, Sophie A. Clarke, Punith Kempegowda, Rima K. Dhillon‐Smith, Puja Thadani, Maureen Busby, Lucy Owusu‐Darkwah, Rachel Marrington, W. Colin Duncan, Robert K. Semple, Richard Quinton, Michael W. O'Reilly   +14 more
wiley   +1 more source

Epidemiology of acromegaly: review of population studies

Pituitary, 2016
Acromegaly is a rare condition necessitating large population studies for the generation of reliable epidemiological data. In this review, we systematically analysed the epidemiological profile of this condition based on recently published population ...
Aikaterini Lavrentaki, A. Paluzzi, J. Wass, N. Karavitaki   +3 more
semanticscholar   +1 more source

Sex differences in acromegaly at diagnosis: A nationwide cohort study and meta‐analysis of the literature

Clinical Endocrinology, 2020
Data on sex differences in acromegaly at the time of diagnosis vary considerably between studies.
J. Dal, Benedikte Grønbaek Skov, M. Andersen, U. Feldt-Rasmussen, C. Feltoft, J. Karmisholt, E. H. Nielsen, O. Dekkers, J. O. Lunde Jørgensen   +8 more
semanticscholar   +1 more source

Incidence of bronchiectasis in patients with acromegaly: a cohort study

Frontiers in Endocrinology
ObjectiveAssociations between acromegaly and several respiratory diseases, such as obstructive lung disease or sleep apnea, have been suggested, but the relationship between bronchiectasis and acromegaly is unclear.
Hyun-Il Gil, Kyungdo Han, Sangmo Hong, Cheol-Young Park   +3 more
doaj   +1 more source

A Zebrafish Acromegaly Model Elevates DNA Damage and Impairs DNA Repair Pathways

Biology, 2018
Acromegaly is a pathological condition due to excess growth hormone (GH) secretion. Acromegaly patients exhibit a deterioration of health and many associated complications, such as cardiovascular issues, arthritis, kidney diseases, muscular weakness, and
Abdalla Elbialy, Shuichi Asakawa, Shugo Watabe, Shigeharu Kinoshita   +3 more
doaj   +1 more source