Results 81 to 90 of about 41,662 (214)

Oral paltusotine, a nonpeptide selective somatostatin receptor 2 agonist: Mass balance, absolute bioavailability and metabolism in healthy participants

open access: yesBritish Journal of Clinical Pharmacology, Volume 91, Issue 7, Page 2070-2079, July 2025.
Abstract Aims Paltusotine is a novel, nonpeptide, selective somatostatin receptor 2 agonist in development for the treatment of acromegaly and carcinoid syndrome. This study investigated the mass balance, routes of excretion, absolute bioavailability and metabolite profile of orally administered paltusotine.
Rosa Luo   +6 more
wiley   +1 more source

Leptin Level in Newly Diagnosed Iraqi Acromegaly Patients

open access: yesAl-Mustansiriyah Journal of Pharmaceutical Sciences, 2018
Acromegaly is a serious endocrine disease resulting from an increase of growth hormone in the blood. Excessive growth hormone secretion may be caused by an adenoma of the pituitary.
Noor Thair Tahir
doaj   +1 more source

A consensus on the diagnosis and treatment of acromegaly complications [PDF]

open access: yes, 2014
In March 2011, the Acromegaly Consensus Group met to revise and update the guidelines on the diagnosis and treatment of acromegaly complications. The meeting was sponsored by the Pituitary Society and the European Neuroendocrinology Association and ...
Bronstein, M. D.   +8 more
core   +1 more source

Expression Profiles of Exosomal miRNAs in Gaucher Patients and Their Association With Severity of Bone Involvement

open access: yesJournal of Inherited Metabolic Disease, Volume 48, Issue 4, July 2025.
ABSTRACT Bone manifestations are one of the most prevalent complications in patients with Gaucher disease (GD). Bone involvement is evaluated by using imaging methods, and there are different scores to assess its severity. However, there are no biomarkers that allow us to predict these manifestations.
Irene Serrano‐Gonzalo   +5 more
wiley   +1 more source

An overview of insulin therapy for the non‐specialist

open access: yesDiabetes, Obesity and Metabolism, Volume 27, Issue S5, Page 3-15, July 2025.
Abstract Nearly all health professionals, whatever their practice or speciality, now have contact with a significant number of insulin‐using people with diabetes. People with type 1 diabetes are nearly universally managed on more complex insulin regimens, increasingly with complex support technology, and with some understanding of the concepts ...
Philip D. Home
wiley   +1 more source

Obstructive Sleep Apnea Syndrome in Acromegaly Before and After Treatment

open access: yesTürk Uyku Tıbbı Dergisi, 2014
Introduction Obstructive sleep apnea syndrome (OSAS) prevalence in acromegaly patients is very common compared with general population. It is thought that OSAS in acromegaly patients evolve because of reversible and irreversible anatomical changes ...
Selda Korkmaz   +5 more
doaj   +1 more source

Upper and lower gastrointestinal tract disorders in patients with newly diagnosed acromegaly

open access: yesAlʹmanah Kliničeskoj Mediciny, 2016
Background: Increased growth hormone production in acromegaly results in enlargement of inner organs, their dysfunction and morphological abnormalities.
A. A. Titaeva   +3 more
doaj   +1 more source

First reports of computed tomographic colonography for the screening of colorectal polyps in acromegalic patients [PDF]

open access: yes, 2008
*Aim:* To analyze the CTC performance for the screening of colorectal polyps in acromegalic patients. *Materials and Methods:* A prospective study of 21 acromegalic patients, 12 male and 9 female, average age 49, who underwent CTC ...
Anke Boeving   +7 more
core   +1 more source

Endocrinologic Control of Men's Sexual Desire and Arousal/Erection [PDF]

open access: yes, 2016
Several hormones and neurotransmitters orchestrate men's sexual response, including the appetitive (sexual desire) and consummative (arousal and penile erection) phases.
Aversa, Antonio   +4 more
core   +1 more source

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