Results 91 to 100 of about 3,330 (184)

Tudor domain containing 7 (Tdrd7) is essential for dynamic ribonucleoprotein (RNP) remodeling of chromatoid bodies during spermatogenesis [PDF]

, 2011
In the male germline in mammals, chromatoid bodies, a specialized assembly of cytoplasmic ribonucleoprotein (RNP), are structurally evident during meiosis and haploidgenesis, but their developmental origin and regulation remain elusive.
Tanaka, T., Hosokawa, M., Vagin, V. V., Reuter, M., Hayashi, E., Mochizuki, A. L., Kitamura, K., Yamanaka, H., Kondoh, G., Okawa, K., Kuramochi-Miyagawa, S., Nakano, T., Sachidanandam, R., Hannon, G. J., Pillai, R. S., Nakatsuji, N., Chuma, S.   +16 more
core   +1 more source

Deciphering the Contribution of Circular RNAs to Age‐Related Decline in Sertoli Cell Survivor

Aging Cell, Volume 24, Issue 6, June 2025.
Sertoli cell survival is regulated by circAbcb9‐ceRNET. Physiologically, the circAbcb9 sponge activity toward miR‐214‐3p ensures the expression of SOX8 and NOTCH2 targets, both crucial in maintaining SC homeostasis. The aging process negatively affects FUS‐dependent backsplicing activity in Sertoli cells leading to circAbcb9 downregulation, and in turn,
Francesco Manfrevola, Nicola Mosca, Vincenza Grazia Mele, Teresa Chioccarelli, Guillaume Martinez, Charles Coutton, Monica Mattia, Mariaceleste Pezzullo, Silvia Fasano, Gilda Cobellis, Nicoletta Potenza, Rosanna Chianese   +11 more
wiley   +1 more source

Parent‐of‐Origin Effects in Childhood Asthma at Seven Years of Age

Genetic Epidemiology, Volume 49, Issue 3, April 2025.
ABSTRACT Childhood asthma is more common among children whose mothers have asthma than among those whose fathers have asthma. The reasons for this are unknown, and we hypothesize that genomic imprinting may partly explain this observation. Our aim is to assess parent‐of‐origin (PoO) effects on childhood asthma by analyzing SNP array genotype data from ...
Yunsung Lee, Miriam Gjerdevik, Astanand Jugessur, Håkon Kristian Gjessing, Elizabeth Corfield, Alexandra Havdahl, Jennifer Ruth Harris, Maria Christine Magnus, Siri Eldevik Håberg, Per Magnus   +9 more
wiley   +1 more source

Genome-wide association study implicates testis-sperm specific FKBP6 as a susceptibility locus for impaired acrosome reaction in stallions.

PLoS Genetics, 2012
Impaired acrosomal reaction (IAR) of sperm causes male subfertility in humans and animals. Despite compelling evidence about the genetic control over acrosome biogenesis and function, the genomics of IAR is as yet poorly understood, providing no ...
Terje Raudsepp, Molly E McCue, Pranab J Das, Lauren Dobson, Monika Vishnoi, Krista L Fritz, Robert Schaefer, Aaron K Rendahl, James N Derr, Charles C Love, Dickson D Varner, Bhanu P Chowdhary   +11 more
doaj   +1 more source

Transmission of mitochondrial DNA following assisted reproduction and nuclear transfer [PDF]

, 2006
Review of the articleMitochondria are the organelles responsible for producing the majority of a cell's ATP and also play an essential role in gamete maturation and embryo development.
Alam, Almeida-Santos, Anderson, Ankel-Simons, Barritt, Bavister, Blok, Boulet, Brenner, Brison, Brown, Brown, Campbell, Chang, Chen, Chen, Chinnery, Chung, Cibelli, Cohen, Cortesini, Cui, Cummins, Cummins, Dailey, Danan, Davis, De Block, Dean, Dumollard, Dunbar, D’Aurelio, E.C. Spikings, Eichenlaub-Ritter, Eisen, El Shourbagy, Falkenberg, Fisher, Fisher, Fulka, Gahan, Giles, Graziewicz, Gyllensten, Hammer, Han, Hance, Hanna, Hauswirth, He, Hecht, Hiendleder, Hiendleder, Hiendleder, Holden, Houghton, Humpherys, Inoue, Irwin, J. Alderson, J.C.St. John, Jansen, Kaneda, Keefe, Kenyon, King, Kirches, Klopstock, Koehler, Kondo, Kondo, Kong, Kong, Kraytsberg, Kvist, Laflamme, Larsson, Larsson, Larsson, Larsson, Leese, Lertrit, Lestienne, Levy, Lin, Liu, Liu, Liu, Lloyd, Ludwig, Luetjens, Machaty, Magnusson, Mancuso, Marchington, Margineantu, May-Panloup, McConnell, McCreath, McKenzie, McKenzie, McKenzie, Meirelles, Meirelles, Meirelles, Meusel, Michaels, Monnat, Moyes, Munne, Munsie, Nagao, Naini, Nakamura, Naviaux, Nishi, Nishigaki, Nishimura, Normile, Ojala, Ono, Palermo, Pfeiffer, Piko, Piko, Ponzetto, Poulton, Reynier, Reynier, Rideout, Rubart, Ruiz-Pesini, Sathananthan, Sathananthan, Sato, Satoh, Sazer, Scarpulla, Schon, Schwartz, Seifer, Sherratt, Shitara, Shoubridge, Siciliano, Smith, Sokolova, Spelbrink, Spiropoulos, St. John, St. John, St. John, St. John, St. John, St. John, St. John, St. John, Steinborn, Steinborn, Steuerwald, Stojanovski, Stojkovic, Sturmey, Sun, Sun, Suomalainen, Sutovsky, Sutovsky, Takeda, Takeda, Takeda, Takeuchi, Takeuchi, Taylor, Tessa, Thompson, Tiranti, Trounce, Trounson, Tsaousis, Vajta, Van Blerkom, Van Blerkom, Van Blerkom, Van Goethem, Wakayama, Wallace, Wallace, Wernig, White, White, Wiesner, Wilding, Wilmut, Xu, Yakes, Yang, Yang, Zhang, Zhao, Zouros   +200 more
core   +2 more sources

The secretion of von Willebrand factor from endothelial cells; an increasingly complicated story. [PDF]

, 2013
von Willebrand factor (VWF) plays key roles in both primary and secondary hemostasis by capturing platelets and chaperoning clotting factor VIII, respectively.
Cutler, D, Nightingale, T
core   +1 more source

Assessment of spermatogenesis in camels via seminiferous tubule staging and testosterone profiling

Asian Pacific Journal of Reproduction
Objective: To investigate the successive morphological stages of spermatogenesis, hormonal regulation, and testosterone profile in dromedary camel reproduction. Methods: Testicular tissue samples were obtained from 12 dromedary bull camels aged 7 to 8 at
Saif Ullah, Abdul Quddus, Quanwei Wei, Wael Ennab, Sheeraz Mustafa, Jiahao Sun, Rahmani Mohammad Malyar, Abdul Baseer, Dagan Mao, Fangxiong Shi   +9 more
doaj   +1 more source

Orexin A-Mediated Modulation of Reproductive Activities in Testis of Normal and Cryptorchid Dogs: Possible Model for Studying Relationships Between Energy Metabolism and Reproductive Control [PDF]

, 2019
Orexin A (OxA) is a neuropeptide produced in the lateral hypothalamus that performs pleiotropic functions in different tissues, including involvement in energy homeostasis and reproductive neuroendocrine functions.
Annunziata, Chiara, Assisi, Loredana, Liguori, Giovanna, Mirabella, Nicola, Pelagalli, Alessandra, Squillacioti, Caterina   +5 more
core   +1 more source

Golgi associated RAB2 interactor protein family contributes to murine male fertility to various extents by assuring correct morphogenesis of sperm heads.

PLoS Genetics
Sperm heads contain not only the nucleus but also the acrosome which is a distinctive cap-like structure located anterior to the nucleus and is derived from the Golgi apparatus.
Haoting Wang, Rie Iida-Norita, Daisuke Mashiko, Anh Hoang Pham, Haruhiko Miyata, Masahito Ikawa   +5 more
doaj   +1 more source

Novel variants in DNAH6 cause male infertility associated with multiple morphological abnormalities of the sperm flagella (MMAF) and ICSI outcomes

Asian Journal of Andrology
Variations in the dynein axonemal heavy chain gene, dynein axonemal heavy chain 6 (DNAH6), lead to multiple morphological abnormalities of the flagella. Recent studies have reported that these deficiencies may result in sperm head deformation.
Zhong-Mei Shao, Yu-Tong Zhu, Meng Gu, Sen-Chao Guo, Hui Yu, Kuo-Kuo Li, Dong-Dong Tang, Yu-Ping Xu, Ming-Rong Lv   +8 more
doaj   +1 more source