Results 71 to 80 of about 1,969 (137)

Assessment of spermatogenesis in camels via seminiferous tubule staging and testosterone profiling

Asian Pacific Journal of Reproduction
Objective: To investigate the successive morphological stages of spermatogenesis, hormonal regulation, and testosterone profile in dromedary camel reproduction. Methods: Testicular tissue samples were obtained from 12 dromedary bull camels aged 7 to 8 at
Saif Ullah, Abdul Quddus, Quanwei Wei, Wael Ennab, Sheeraz Mustafa, Jiahao Sun, Rahmani Mohammad Malyar, Abdul Baseer, Dagan Mao, Fangxiong Shi   +9 more
doaj   +1 more source

Novel variants in DNAH6 cause male infertility associated with multiple morphological abnormalities of the sperm flagella (MMAF) and ICSI outcomes

Asian Journal of Andrology
Variations in the dynein axonemal heavy chain gene, dynein axonemal heavy chain 6 (DNAH6), lead to multiple morphological abnormalities of the flagella. Recent studies have reported that these deficiencies may result in sperm head deformation.
Zhong-Mei Shao, Yu-Tong Zhu, Meng Gu, Sen-Chao Guo, Hui Yu, Kuo-Kuo Li, Dong-Dong Tang, Yu-Ping Xu, Ming-Rong Lv   +8 more
doaj   +1 more source

Golgi associated RAB2 interactor protein family contributes to murine male fertility to various extents by assuring correct morphogenesis of sperm heads.

PLoS Genetics
Sperm heads contain not only the nucleus but also the acrosome which is a distinctive cap-like structure located anterior to the nucleus and is derived from the Golgi apparatus.
Haoting Wang, Rie Iida-Norita, Daisuke Mashiko, Anh Hoang Pham, Haruhiko Miyata, Masahito Ikawa   +5 more
doaj   +1 more source

Whole exome sequencing identifies a new DPY19L2 variant c.1232_1233insA in Tunisian infertile patient with globozoospermia

Middle East Fertility Society Journal
Background Globozoospermia is a rare male infertility disorder characterized by the presence in the ejaculate of round-headed sperm cells lacking an acrosome, a crucial structure for fertilization.
Wiem Ayed, Nicolas Thierry-Mieg, Wajh Hammami, Meriem Ben Khalifa, Sonia Mnallah, Hanène Eloumi, Amel Zhioua, Anis Chaker, Fethi Zhioua, Pierre F. Ray, Ahlem Amouri   +10 more
doaj   +1 more source

Single-Cell Transcriptomic Profiling of the Mouse Testicular Germ Cells Reveals Important Role of Phosphorylated GRTH/DDX25 in Round Spermatid Differentiation and Acrosome Biogenesis during Spermiogenesis. [PDF]

Int J Mol Sci, 2023
Kavarthapu R, Anbazhagan R, Pal S, Dufau ML.   +3 more
europepmc   +1 more source

ISEV2026 Abstract Book

Journal of Extracellular Vesicles, Volume 15, Issue S1, June 2026.
wiley   +1 more source

Protamine 2 deficiency results in Septin 12 abnormalities

Frontiers in Cell and Developmental Biology
There is a well-established link between abnormal sperm chromatin states and poor motility, however, how these two processes are interdependent is unknown.
Ondrej Sanovec, Ondrej Sanovec, Michaela Frolikova, Veronika Kraus, Jana Vondrakova, Maryam Qasemi, Daniela Spevakova, Ondrej Simonik, Lindsay Moritz, Drew Lewis Caswell, Frantisek Liska, Lukas Ded, Jiri Cerny, Tomer Avidor-Reiss, Tomer Avidor-Reiss, Saher Sue Hammoud, Hubert Schorle, Pavla Postlerova, Klaus Steger, Katerina Komrskova, Katerina Komrskova   +20 more
doaj   +1 more source

Meiotic divisions and round spermatid formation do not require centriole duplication in mice.

PLoS Genetics
Centrosomes, composed of centrioles and pericentriolar matrix proteins, are traditionally viewed as essential microtubule-organizing centers (MTOCs) that facilitate bipolar spindle formation and chromosome segregation during spermatogenesis.
Marnie W Skinner, Paula B Nhan, Carter J Simington, Philip W Jordan   +3 more
doaj   +1 more source

BDE-209 toxicity: From spermiogenesis to sexual maturity in F1 male mice

Ecotoxicology and Environmental Safety
Most studies of enviromental toxic chemicals focused on the meiosis stage during spermatogenesis, however, the research on the spermiogenesis damage phenotype of BDE-209 is limited.
Xin Gao, Qi Zheng, Siju Chen, Huan He, Yu Wei, Taifa Zhang, Yi Wang, Bo Wang, Dake Huang, Shengquan Zhang, Sumei Zhang, Jinxia Zhai   +11 more
doaj   +1 more source

Coiled-coil domain-containing 38 is required for acrosome biogenesis and fibrous sheath assembly in mice

Journal of Genetics and Genomics
During spermiogenesis, haploid spermatids undergo dramatic morphological changes to form slender sperm flagella and cap-like acrosomes, which are required for successful fertilization. Severe deformities in flagella cause a male infertility syndrome, multiple morphological abnormalities of the flagella (MMAF), while acrosomal hypoplasia in some cases ...
Yaling Wang, Xueying Huang, Guoying Sun, Jingwen Chen, Bangguo Wu, Jiahui Luo, Shuyan Tang, Peng Dai, Feng Zhang, Jinsong Li, Lingbo Wang   +10 more
openaire   +2 more sources