Results 71 to 80 of about 3,330 (184)
Impact of Marine Drugs on Cytoskeleton-Mediated Reproductive Events [PDF]
Marine organisms represent an important source of novel bioactive compounds, often showing unique modes of action. Such drugs may be useful tools to study complex processes such as reproduction; which is characterized by many crucial steps that start at ...
Francesco Silvestre +250 more
core +1 more source
Glycoprotein 88 (GP88) is a secreted biomarker that is overexpressed in various cancers, neurological diseases such as Alzheimer's and Dementia, and inflammatory disorders. A disposable, rapid testing device for GP88 detection provides immediate marker‐level results, helping doctors monitor disease progression and therapy effectiveness. When optimized,
Elham Rezaee +2 more
wiley +1 more source
An update on the potential for male contraception : emerging options [PDF]
The human population continues to grow and is estimated to rise to 10.1 billion by the end of the century. Therefore, there is still an unmet need for safe and highly effective contraceptive options for both men and women.
Alsaadi, Manal +5 more
core +1 more source
Infertility has emerged as a significant issue in contemporary society, with its prevalence on the rise globally. According to international statistics, men are identified as the contributing factor in nearly 50% of infertility cases. Noncoding RNAs (ncRNAs) serve as essential functional components within epigenetic frameworks, significantly ...
Mohammadreza Saberiyan +4 more
wiley +1 more source
Kinesin-6 KIF20A is essential for microtubule organization and central spindle assembly during cytokinesis. However, the functions of KIF20A in meiotic division and spermatogenesis remain elusive. Here, we report that kinesin-6 KIF20A locates at the microtubules in mouse spermatogenic cells and co-localizes with the spindle midzone and midbody.
Zhen-Yu, She +7 more
openaire +2 more sources
Absolute proteomic quantification reveals design principles of sperm flagellar chemosensation [PDF]
© The Author(s), 2020. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Troetschel, C., Hamzeh, H., Alvarez, L., Pascal, R., Lavryk, F., Boenigk, W., Koerschen, H.
Alvarez, Luis +14 more
core +1 more source
P4‐ATPases as Phospholipid Flippases: From Membrane Dynamics to Human Disorders
ABSTRACT P4‐ATPases (P4 subfamily of P‐type ATPases) flippase complex includes an α‐subunit responsible for catalysis and a supporting β‐subunit, which consumes energy by catalyzing the hydrolysis of ATP, thereby facilitating the translocation of aminophospholipids from the outer to the inner leaflet of cellular membranes to maintain the asymmetric ...
Guangyi Chen, Yeming Yang, Xianjun Zhu
wiley +1 more source
Teratozoospermia: spotlight on the main genetic actors in the human [PDF]
BACKGROUND Male infertility affects >20 million men worldwide and represents a major health concern. Although multifactorial, male infertility has a strong genetic basis which has so far not been extensively studied.
Arnoult, Christophe +4 more
core
Ca2+ ionophore A23187 can make mouse spermatozoa capable of fertilizing in vitro without activation of cAMP-dependent phosphorylation pathways [PDF]
Ca2+ ionophore A23187 is known to induce the acrosome reaction of mammalian spermatozoa, but it also quickly immobilizes them. Although mouse spermatozoa were immobilized by this ionophore, they initiated vigorous motility (hyperactivation) soon after ...
Darszon, Alberto +6 more
core +2 more sources
Role of Seminal Exosomes in Reproduction
ABSTRACT Exosomes are small lipid bilayer vesicles, ranging from 30 to 150 nm in diameter, that are secreted by various cells and facilitate intercellular communication. They originate from the endosomal system and release their contents into the extracellular environment.
Shayesteh Mehdinejadiani +9 more
wiley +1 more source

