Results 61 to 70 of about 1,969 (137)
Andrologia, Volume 2026, Issue 1, 2026.Background Male infertility is a complex condition with significant genetic heterogeneity. Globozoospermia, a rare form of teratozoospermia characterized by round‐headed sperm, is frequently associated with mutations in the DPY19L2 gene. While the link between DPY19L2 and infertility is established, the co‐occurrence of male infertility and congenital ...
Hongjing Li +6 more
wiley +1 more source
Andrologia, Volume 2026, Issue 1, 2026.Infertility has emerged as a significant issue in contemporary society, with its prevalence on the rise globally. According to international statistics, men are identified as the contributing factor in nearly 50% of infertility cases. Noncoding RNAs (ncRNAs) serve as essential functional components within epigenetic frameworks, significantly ...
Mohammadreza Saberiyan +4 more
wiley +1 more source
Biochemical and Biophysical Research Communications, 2002 To identify new genes that could be involved in the differentiation and function of male germ cells, we have screened a murine testis cDNA library and isolated a clone that was named Tep22. The gene encoding Tep22 consists of three exons and is localized in the telomeric region of mouse chromosome 12.
Neesen, J. +6 more
openaire +3 more sources
P4‐ATPases as Phospholipid Flippases: From Membrane Dynamics to Human Disorders
Medicine Bulletin, Volume 1, Issue 2, Page 121-135, December 2025.ABSTRACT P4‐ATPases (P4 subfamily of P‐type ATPases) flippase complex includes an α‐subunit responsible for catalysis and a supporting β‐subunit, which consumes energy by catalyzing the hydrolysis of ATP, thereby facilitating the translocation of aminophospholipids from the outer to the inner leaflet of cellular membranes to maintain the asymmetric ...
Guangyi Chen, Yeming Yang, Xianjun Zhu
wiley +1 more source
Targeting and fusion proteins during mammalian spermiogenesis
Biological Research, 2001 Regulated exocytosis is controlled by internal and external signals. The molecular machinery controlling the sorting from the newly synthesized vesicles from the Golgi apparatus to the plasma membrane play a key role in the regulation of both the number ...
JOÃO RAMALHO-SANTOS, RICARDO D. MORENO
doaj
Role of Seminal Exosomes in Reproduction
Journal of Cellular Physiology, Volume 240, Issue 11, November 2025.ABSTRACT Exosomes are small lipid bilayer vesicles, ranging from 30 to 150 nm in diameter, that are secreted by various cells and facilitate intercellular communication. They originate from the endosomal system and release their contents into the extracellular environment.
Shayesteh Mehdinejadiani +9 more
wiley +1 more source
Molecular Nutrition &Food Research, Volume 69, Issue 22, November 2025.This review highlights the emerging connection between paternal nutrition‐induced sperm epigenetic changes and placental phenotypes that may influence offspring metabolic health. An accompanying interactive ShinyApp allows exploration of these sperm–placenta gene networks, a framework for future research seeking to explore candidate biomarkers or ...
David A. Skerrett‐Byrne +6 more
wiley +1 more source
Reproduction in Domestic Animals, Volume 60, Issue S3, September 2025.ABSTRACT Extracellular Vesicles (EVs) are small, membrane‐bound particles released by cells into biological fluids, where they function as mediators of intercellular communication. These vesicles transport a diverse array of bioactive molecules, including proteins, lipids, and nucleic acids, and play essential roles in regulating physiological and ...
Alireza Fazeli +3 more
wiley +1 more source
Molecular Ecology Resources, Volume 25, Issue 6, August 2025.ABSTRACT Genomic incompatibilities and differential ecological adaptation are thought to be fundamental mechanisms of speciation. In this study, we generated a chromosome‐scale reference genome and annotation for Gopherus morafkai , the Sonoran Desert tortoise, and conducted a detailed analysis of genes under positive selection with its sister species,
Sarah M. Baty +6 more
wiley +1 more source
PLoS Genetics, 2012 Impaired acrosomal reaction (IAR) of sperm causes male subfertility in humans and animals. Despite compelling evidence about the genetic control over acrosome biogenesis and function, the genomics of IAR is as yet poorly understood, providing no ...
Terje Raudsepp +11 more
doaj +1 more source