Results 51 to 60 of about 3,330 (184)
The role of Merlin in spermatogenesis [PDF]
, 2008 Background Drosophila Merlin, the homolog of the human Neurofibromatosis 2 (NF2) gene, is important for the regulation of cell proliferation and receptor endocytosis. Male flies carrying a Mer3 allele, a missense mutation (Met177→Ile) in the Merlin gene,
Omelyanchuk Leonid V +6 more
core +1 more source
Cells, 2023 Studies on the gene regulation of spermatogenesis are of unusual significance for maintaining male reproduction and treating male infertility. Here, we have demonstrated, for the first time, that a loss of ZBTB40 function leads to abnormalities in the ...
Yinghong Cui +3 more
doaj +1 more source
Functional human sperm capacitation requires both bicarbonate dependent-PKA activation and down-regulation of Ser/Thr phosphatases by Src family kinases [PDF]
, 2013 In all mammalian species studied so far, sperm capacitation correlates with an increase in protein tyrosine (Tyr) phosphorylation mediated by a bicarbonate-dependent cAMP/PKA pathway.
Battistone, Maria Agustina +6 more
core +1 more source
Reproductive Medicine and Biology, 2020 Background During spermatogenesis, cytoskeletal elements are essential for spermatogenic cells to change morphologically and translocate in the seminiferous tubule.
Tetsuji Soda +3 more
doaj +1 more source
Nuclear morphologies: their diversity and functional relevance. [PDF]
, 2017 Studies of chromosome and genome biology often focus on condensed chromatin in the form of chromosomes and neglect the non-dividing cells. Even when interphase nuclei are considered, they are often then treated as interchangeable round objects.
core +2 more sources
Journal of Animal Science and Biotechnology, 2023 Background Comparative and comprehensive omics studies have recently been conducted to provide a comprehensive understanding of the biological mechanisms underlying infertility.
Yoo-Jin Park +2 more
doaj +1 more source
Intra-Testicular Signals Regulate Germ Cell Progression and Production of Qualitatively Mature Spermatozoa in Vertebrates [PDF]
, 2014 Spermatogenesis, a highly conserved process in vertebrates, is mainly under the hypothalamic-pituitary control, being regulated by the secretion of pituitary gonadotropins, FSH and LH, in response to stimulation exerted by Gonadotropin Releasing Hormone (
Gilda Cobellis +6 more
core +2 more sources
Fundamental Mechanisms of Sperm Production: The Role of Microtubules
Fertility & Reproduction, 2023 Spermatogenesis is a feat of unparalleled biological scale and complexity. At any one time, the human testis harbours millions of germ cells in a continuous progression through multiple rounds of mitosis and meiosis, followed by a series of dramatic ...
Jessica Dunleavy
doaj +1 more source
The use of deidentified organ donor testes for research
Andrology, EarlyView.Abstract Our knowledge of testis development and function mainly comes from research using mammalian model organisms, primarily the mouse. However, there are integral differences between men and other mammalian species regarding cellular composition and expression profiles during fetal and post‐natal testis development and in the mature testis ...
Marina V. Pryzhkova +4 more
wiley +1 more source
The Mechanism of Heat Stress Resistance During Spermatogenesis in Turpan Black Sheep
Frontiers in Veterinary Science, 2022 Heat stress can affect the reproductive function of livestock and cause harm to animal production, which can seriously damage the economic interests of livestock producers.
Yukun Song +9 more
doaj +1 more source